Publications
Diverse Clinical Isolates of Mycobacterium tuberculosis Develop Macrophage-Induced Rifampin Tolerance." The Journal of Infectious Diseases. 2019;219:1554-1558.
"TB vaccines; promoting rapid and durable protection in the lung." Curr. Opin. Immunol.. 2015;35:55-62.
"Systems proteomics approaches to study bacterial pathogens: application to Mycobacterium tuberculosis." Curr. Opin. Microbiol.. 2017;39:64-72.
"Cell envelope stress in mycobacteria is regulated by the novel signal transduction ATPase IniR in response to trehalose." PLoS Genet.. 2017;13(12):e1007131.
"Alveolar Macrophages Provide an Early Mycobacterium tuberculosis Niche and Initiate Dissemination." Cell Host Microbe. 2018;24(3):439-446.e4.
"Going beyond gamma for TB protection." Nat Microbiol. 2018;3(11):1194-1195.
"Cutting Edge: Bacillus Calmette–Guérin–Induced T Cells Shape Mycobacterium tuberculosis Infection before Reducing the Bacterial Burden." The Journal of Immunology. 2019;203:807-812.
"BCG-induced T cells shape Mycobacterium tuberculosis infection before reducing the bacterial burden." bioRxiv. 2019.
"Interdependence between Interleukin-1 and Tumor Necrosis Factor Regulates TNF-Dependent Control of Mycobacterium tuberculosis Infection." Immunity. 2015;43(6):1125-36.
"Immunometabolic Signatures Predict Risk of Progression to Active Tuberculosis and Disease Outcome." Front Immunol. 2019;10:527.
"Prevention of tuberculosis in rhesus macaques by a cytomegalovirus-based vaccine." Nat. Med.. 2018;24(2):130-143.
"Mycobacterial Acid Tolerance Enables Phagolysosomal Survival and Establishment of Tuberculous Infection In Vivo." Cell Host Microbe. 2016;20(2):250-8.
"Transcriptomic Signatures Predict Regulators of Drug Synergy and Clinical Regimen Efficacy against Tuberculosis." mBio. 2019;10(6).
"Transcriptional regulator-induced phenotype screen reveals drug potentiators in Mycobacterium tuberculosis." Nat Microbiol. 2020.
"Integrated Modeling of Gene Regulatory and Metabolic Networks in Mycobacterium tuberculosis." PLoS Comput. Biol.. 2015;11(11):e1004543.
"The DNA-binding network of Mycobacterium tuberculosis." Nat Commun. 2015;6:5829.
"ICOS and Bcl6-dependent pathways maintain a CD4 T cell population with memory-like properties during tuberculosis." J. Exp. Med.. 2015;212(5):715-28.
"Antigen Availability Shapes T Cell Differentiation and Function during Tuberculosis." Cell Host Microbe. 2017;21(6):695-706.e5.
"Contained Mycobacterium tuberculosis infection induces concomitant and heterologous protection." PLoS Pathog. 2020;16(7):e1008655.
"Elucidation of host-pathogen protein-protein interactions to uncover mechanisms of host cell rewiring." Curr. Opin. Microbiol.. 2017;39:7-15.
"Genetic Diversity in Clinical Isolates and Resulting Outcomes of Tuberculosis Infection and Disease." Annu Rev Genet. 2020.
"Network analysis identifies Rv0324 and Rv0880 as regulators of bedaquiline tolerance in Mycobacterium tuberculosis." Nat Microbiol. 2016;1(8):16078.
"A high-resolution network model for global gene regulation in Mycobacterium tuberculosis." Nucleic Acids Res.. 2014;42(18):11291-303.
"Path-seq identifies an essential mycolate remodeling program for mycobacterial host adaptation." Molecular Systems Biology. 2019;15:e8584.
"Intricate Genetic Programs Controlling Dormancy in Mycobacterium tuberculosis." Cell Rep. 2020;31(4):107577.
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