Publications
Alveolar macrophages generate a noncanonical NRF2-driven transcriptional response in vivo." Sci Immunol. 2019;4(37).
"Alveolar Macrophages Provide an Early Mycobacterium tuberculosis Niche and Initiate Dissemination." Cell Host Microbe. 2018;24(3):439-446.e4.
"Antigen Availability Shapes T Cell Differentiation and Function during Tuberculosis." Cell Host Microbe. 2017;21(6):695-706.e5.
"BCG-induced T cells shape Mycobacterium tuberculosis infection before reducing the bacterial burden." bioRxiv. 2019.
"Cell envelope stress in mycobacteria is regulated by the novel signal transduction ATPase IniR in response to trehalose." PLoS Genet.. 2017;13(12):e1007131.
"A comprehensive map of genome-wide gene regulation in Mycobacterium tuberculosis." Scientific Data. 2015;2: - . (8.9 KB) (157.5 KB) (337.5 KB) (1.33 MB)
"Contained Mycobacterium tuberculosis infection induces concomitant and heterologous protection." PLoS Pathog. 2020;16(7):e1008655.
"Cutting Edge: Bacillus Calmette–Guérin–Induced T Cells Shape Mycobacterium tuberculosis Infection before Reducing the Bacterial Burden." The Journal of Immunology. 2019;203:807-812.
"Diverse Clinical Isolates of Mycobacterium tuberculosis Develop Macrophage-Induced Rifampin Tolerance." The Journal of Infectious Diseases. 2019;219:1554-1558.
"The DNA-binding network of Mycobacterium tuberculosis." Nat Commun. 2015;6:5829.
"Elucidation of host-pathogen protein-protein interactions to uncover mechanisms of host cell rewiring." Curr. Opin. Microbiol.. 2017;39:7-15.
"Flow Cytometry Analysis and Fluorescence-activated Cell Sorting of Myeloid Cells from Lung and Bronchoalveolar Lavage Samples from -infected Mice." Bio Protoc. 2020;10(10).
"Genetic Diversity in Clinical Isolates and Resulting Outcomes of Tuberculosis Infection and Disease." Annu Rev Genet. 2020.
"Going beyond gamma for TB protection." Nat Microbiol. 2018;3(11):1194-1195.
"A high-resolution network model for global gene regulation in Mycobacterium tuberculosis." Nucleic Acids Res.. 2014;42(18):11291-303.
"Host blood RNA signatures predict the outcome of tuberculosis treatment." Tuberculosis (Edinb). 2017;107:48-58.
"ICOS and Bcl6-dependent pathways maintain a CD4 T cell population with memory-like properties during tuberculosis." J. Exp. Med.. 2015;212(5):715-28.
"Immunometabolic Signatures Predict Risk of Progression to Active Tuberculosis and Disease Outcome." Front Immunol. 2019;10:527.
"Integrated Modeling of Gene Regulatory and Metabolic Networks in Mycobacterium tuberculosis." PLoS Comput. Biol.. 2015;11(11):e1004543.
"Interdependence between Interleukin-1 and Tumor Necrosis Factor Regulates TNF-Dependent Control of Mycobacterium tuberculosis Infection." Immunity. 2015;43(6):1125-36.
"Intricate Genetic Programs Controlling Dormancy in Mycobacterium tuberculosis." Cell Rep. 2020;31(4):107577.
"Landscape of coordinated immune responses to H1N1 challenge in humans." J Clin Invest. 2020;130(11):5800-5816.
"Mapping and manipulating the Mycobacterium tuberculosis transcriptome using a transcription factor overexpression-derived regulatory network." Genome Biol.. 2014;15(11):502. (19.36 MB) (20.15 MB)
"MiR-155-regulated molecular network orchestrates cell fate in the innate and adaptive immune response to Mycobacterium tuberculosis." Proc. Natl. Acad. Sci. U.S.A.. 2016;113(41):E6172-E6181.
"Mycobacterial Acid Tolerance Enables Phagolysosomal Survival and Establishment of Tuberculous Infection In Vivo." Cell Host Microbe. 2016;20(2):250-8.
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