MSMEG_1109 MSMEG_1109 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase (SEPHCHC synthase) (EC 2.2.1.9) (Menaquinone biosynthesis protein MenD)
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

Help

Summary

	Locus Tag	Symbol	Synonyms	Product	Protein Synonyms	Start	End	Strand	PubMed ID
MSMEG_1109	MSMEG_1109	menD	menD, MSMEG_1109, MSMEI_1077		2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase (SEPHCHC synthase) (EC 2.2.1.9) (Menaquinone biosynthesis protein MenD)				17295914, 18955433

Regulatory Modules

	Residual	Motif 1	Expression Plot
msm_bicluster_0007	0.57
msm_bicluster_0505	0.57

XReference

Uniprot	NCBI Gene	NCBI Protein	EnsemblBacteria	InterPro	EggNOG	OrthoDB
A0QRG5	4537235;	WP_014876969.1, YP_885503.1	ABK73707, AFP37557	IPR004433, IPR029061, IPR012001	ENOG4105C4A, COG1165	EOG6NWBQW

Mutations

Line	Position	Effect	Impact	Class	Percent Frequency	AA

Transposon mutants

Title	Insert	TAG Module
NA

Homology

Orthologues	Paralogues

Functions

Catalytic Activity	KEGG Ontology	Pathways
Isochorismate + 2-oxoglutarate = 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate + CO(2), ECO:0000255|HAMAP-Rule:MF_01659}.	msb:LJ00_05515, msg:MSMEI_1077, msm:MSMEG_1109	Quinol/quinone metabolism, 1,4-dihydroxy-2-naphthoate biosynthesis, 1,4-dihydroxy-2-naphthoate from chorismate: step 2/7. {ECO:0000255|HAMAP-Rule:MF_01659}., Quinol/quinone metabolism, menaquinone biosynthesis. {ECO:0000255|HAMAP-Rule:MF_01659}.

Product Synonyms

Product (LegacyBRC)	Product (RefSeq)

Operon

Refseq

GI Number	Accession	Blast	Conserved Domains

GO Terms

GO:0070204 GO:0000287 GO:0030145 GO:0009234 GO:0030976 -

GO:0070204

GO:0000287

GO:0030145

GO:0009234

GO:0030976

String Network

Link to STRINGS	STRINGS Network
MSMEG_1109

Add comment

Log in to post comments