36522 (TOP2) PLN03128
Thalassiosira pseudonana

Genome Browser

Summary

Chromosome Product Transcript Start End Strand Short Name
36522 chr_10 (TOP2) PLN03128 749141 753294 + PLN03128

Synonyms

Hierarchical Clustering

Expression Profile Conditional Changes Cluster Dendrogram
Thaps_hclust_0091

Motif-Guided Biclusters

Normalized Mean Residue
Thaps_bicluster_0099
 0.44

Most Highly Correlated Transcripts

bd439

(bd439) POLBc_alpha
0.9813

bd1983

(bd1983) RecA-like_NTPases superfamily
0.9647

bd950

(bd950) NA
0.9544

bd1173

(bd1173) S_TKc
0.9449

bd1214

(bd1214) KISc_C_terminal
0.9361

bd1081

(bd1081) NA
0.9328

bd843

(bd843) NA
0.9278

bd463

(bd463) Aa_trans superfamily
0.9147

bd760

(bd760) ZnMc superfamily
0.9065

bd1893

(bd1893) NA
0.9

Conserved Domains

Name CD Accession Definition Superfamily Bitscore E-Value From - To Hit Type PSSM ID
TOP4c superfamily DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC... - 435.073 1.30E-139 770 - 1229 superfamily 238111
TOP4c superfamily DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC... - 435.073 1.30E-139 770 - 1229 superfamily 238111
TOPRIM_TopoIIA TOPRIM_TopoIIA: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type... cl00718 237.198 3.44E-72 518 - 638 specific 173785
TOPRIM superfamily Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA,... - 237.198 3.44E-72 518 - 638 superfamily 260587
TopoIIA_Trans_ScTopoIIA TopoIIA_Trans_ScTopoIIA: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type... cl02783 228.71 8.32E-69 336 - 481 specific 239563
TopoII_MutL_Trans superfamily MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-... - 228.71 8.32E-69 336 - 481 superfamily 261445
PLN03128 DNA topoisomerase 2; Provisional - 2079.71 0 84 - 1234 multi-dom 215593

Homologs in Other Species

T. pseudonana P. tricornutum P. tricornutum DiatomCyc F. cylindrus Pseudo-nitzschia multiseries E. huxleyi C. reinhardtii A. thaliana P. sojae
Not available Not available Not available 235795 Not available Not available Not available 559851

KEGG

KEGG description KEGG Pathway
Not available Not available

GO Terms

GO:0003677 GO:0003918 GO:0005524 GO:0006259 GO:0006265 GO:0005634 -

GO:0003677

DNA binding

Details: 
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO Category: 
MF

GO:0003918

DNA topoisomerase type II (ATP-hydrolyzing) activity

Details: 
Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
GO Category: 
MF

GO:0005524

ATP binding

Details: 
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
GO Category: 
MF

GO:0006259

DNA metabolic process

Details: 
Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.
GO Category: 
BP

GO:0006265

DNA topological change

Details: 
The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number.
GO Category: 
BP

GO:0005634

nucleus

Details: 
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
GO Category: 
CC

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