38110 P4Hc
Thalassiosira pseudonana

Genome Browser

Summary

Chromosome Product Transcript Start End Strand Short Name
38110 chr_18 P4Hc 189735 193608 + P4Hc

Synonyms

NCBI ID Ensembl Genomes exon ID
7442938 Thaps38110.1, Thaps38110.2

Hierarchical Clustering

Expression Profile Conditional Changes Cluster Dendrogram
Thaps_hclust_0371

Motif-Guided Biclusters

Normalized Mean Residue
Thaps_bicluster_0086
 0.47

Most Highly Correlated Transcripts

30701

PRK05279
0.9123

36007

Aldolase_II superfamily
0.8944

bd1095

(bd1095) NA
0.894

bd1094

(bd1094) FH2 superfamily
0.884

22673

NA
0.8798

24525

hypothetical protein
0.875

261400

NA
0.8749

36641

Aldolase_Class_I superfamily
0.8738

4108

hypothetical protein
0.8638

7446

hypothetical protein
0.8621

Conserved Domains

Name CD Accession Definition Superfamily Bitscore E-Value From - To Hit Type PSSM ID
P4Hc Prolyl 4-hydroxylase alpha subunit homologues; Mammalian enzymes catalyse hydroxylation of collagen... cl17304 121.341 6.12E-31 1076 - 1253 specific 214780
2OG-FeII_Oxy_3 superfamily 2OG-Fe(II) oxygenase superfamily; This family contains members of the 2-oxoglutarate (2OG) and Fe(... - 121.341 6.12E-31 1076 - 1253 superfamily 266616

Homologs in Other Species

T. pseudonana P. tricornutum P. tricornutum DiatomCyc F. cylindrus Pseudo-nitzschia multiseries E. huxleyi C. reinhardtii A. thaliana P. sojae
Not available Not available 179671 321773 Not available Not available Not available Not available

KEGG

KEGG description KEGG Pathway
Metabolic pathways map01100

GO Terms

GO:0016706 GO:0019538 GO:0004656 GO:0016222 -

GO:0016706

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors

Details: 
Catalysis of the reaction: A + 2-oxoglutarate + O2 = B + succinate + CO2. This is an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and one atom of oxygen is incorporated into each donor.
GO Category: 
MF

GO:0019538

protein metabolic process

Details: 
The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
GO Category: 
BP

GO:0004656

procollagen-proline 4-dioxygenase activity

Details: 
Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2.
GO Category: 
MF

GO:0016222

procollagen-proline 4-dioxygenase complex

Details: 
A protein complex that catalyzes the formation of procollagen trans-4-hydroxy-L-proline and succinate from procollagen L-proline and 2-oxoglutarate, requiring Fe2+ and ascorbate. Contains two alpha subunits that contribute to most parts of the catalytic sites, and two beta subunits that are identical to protein-disulfide isomerase.
GO Category: 
CC

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