38171 UDG_F1
Thalassiosira pseudonana

Genome Browser

Summary

Chromosome Product Transcript Start End Strand Short Name
38171 chr_18 UDG_F1 125949 126854 - UDG_F1

Synonyms

NCBI ID Ensembl Genomes exon ID
7450935 Thaps38171.3, Thaps38171.1, Thaps38171.2

Hierarchical Clustering

Expression Profile Conditional Changes Cluster Dendrogram
Thaps_hclust_0335

Motif-Guided Biclusters

Normalized Mean Residue
Thaps_bicluster_0061
 0.42

Most Highly Correlated Transcripts

8498

Ribosomal_L9_N
0.84

263961

(Tp_Myb1R1) MYB DNA binding protein/ transcription factor-like protein
0.8379

1585

MPP_PP2A_PP4_PP6
0.8346

11441

hypothetical protein
0.8316

6997

hypothetical protein
0.8309

25516

hypothetical protein
0.8303

39741

(APM3) AP-3_Mu3_Cterm
0.8291

16114

PLN02350
0.8286

2731

hypothetical protein
0.8279

7370

hypothetical protein
0.8269

Conserved Domains

Name CD Accession Definition Superfamily Bitscore E-Value From - To Hit Type PSSM ID
UDG_F1 Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Uracil-DNA glycosylases (UDGs) are DNA repair... cl00483 287.09 1.81E-98 1 - 205 specific 198425
UDG_like superfamily Uracil-DNA glycosylases (UDG) and related enzymes; Uracil-DNA glycosylases (UDG) catalyzes the... - 287.09 1.81E-98 1 - 205 superfamily 260455

Homologs in Other Species

T. pseudonana P. tricornutum P. tricornutum DiatomCyc F. cylindrus Pseudo-nitzschia multiseries E. huxleyi C. reinhardtii A. thaliana P. sojae
Not available Not available 208373 294134 Not available Not available Not available Not available

KEGG

KEGG description KEGG Pathway
Not available Not available

GO Terms

GO:0004844 GO:0006281 GO:0016799 GO:0017065 GO:0019104 -

GO:0004844

uracil DNA N-glycosylase activity

Details: 
Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases in DNA that result from the deamination of cytosine or the misincorporation of dUTP opposite an adenine.
GO Category: 
MF

GO:0006281

DNA repair

Details: 
The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
GO Category: 
BP

GO:0016799

hydrolase activity, hydrolyzing N-glycosyl compounds

Details: 
Catalysis of the hydrolysis of any N-glycosyl bond.
GO Category: 
MF

GO:0017065

single-strand selective uracil DNA N-glycosylase activity

Details: 
Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases present in single-stranded DNA.
GO Category: 
MF

GO:0019104

DNA N-glycosylase activity

Details: 
Catalysis of the removal of damaged bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.
GO Category: 
MF

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