36522 (TOP2) PLN03128
Thalassiosira pseudonana

Chromosome Product Transcript Start End Strand Short Name
36522 chr_10 (TOP2) PLN03128 749141 753294 + PLN03128
Expression Profile Conditional Changes Cluster Dendrogram
Thaps_hclust_0091
Normalized Mean Residue
Thaps_bicluster_0099
0.44
(bd439) POLBc_alpha
0.9813
(bd1983) RecA-like_NTPases superfamily
0.9647
(bd950) NA
0.9544
(bd1173) S_TKc
0.9449
(bd1214) KISc_C_terminal
0.9361
(bd1081) NA
0.9328
(bd843) NA
0.9278
(bd463) Aa_trans superfamily
0.9147
(bd760) ZnMc superfamily
0.9065
(bd1893) NA
0.9
Name CD Accession Definition Superfamily Bitscore E-Value From - To Hit Type PSSM ID
TOP4c superfamily DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC... - 435.073 1.30E-139 770 - 1229 superfamily 238111
TOP4c superfamily DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC... - 435.073 1.30E-139 770 - 1229 superfamily 238111
TOPRIM_TopoIIA TOPRIM_TopoIIA: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type... cl00718 237.198 3.44E-72 518 - 638 specific 173785
TOPRIM superfamily Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA,... - 237.198 3.44E-72 518 - 638 superfamily 260587
TopoIIA_Trans_ScTopoIIA TopoIIA_Trans_ScTopoIIA: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type... cl02783 228.71 8.32E-69 336 - 481 specific 239563
TopoII_MutL_Trans superfamily MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-... - 228.71 8.32E-69 336 - 481 superfamily 261445
PLN03128 DNA topoisomerase 2; Provisional - 2079.71 0 84 - 1234 multi-dom 215593
T. pseudonana P. tricornutum P. tricornutum DiatomCyc F. cylindrus Pseudo-nitzschia multiseries E. huxleyi C. reinhardtii A. thaliana P. sojae
Not available Not available Not available 235795 Not available Not available Not available 559851
KEGG description KEGG Pathway
Not available Not available
GO:0003677 GO:0003918 GO:0005524 GO:0006259 GO:0006265 GO:0005634 -

DNA binding

Details: 
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO Category: 
MF

DNA topoisomerase type II (ATP-hydrolyzing) activity

Details: 
Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
GO Category: 
MF

ATP binding

Details: 
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
GO Category: 
MF

DNA metabolic process

Details: 
Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.
GO Category: 
BP

DNA topological change

Details: 
The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number.
GO Category: 
BP

nucleus

Details: 
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
GO Category: 
CC
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