polypeptide N-acetylgalactosaminyltransferase activity
id: GO:0004653
name: polypeptide N-acetylgalactosaminyltransferase activity
namespace: molecular_function
type: go
obsolete: False
Description: Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosaminyl-polypeptide. This reaction is the modification of serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid; it is the first step in O-glycan biosynthesis.
Parent Functions
id | name |
---|---|
GO:0008376 | acetylgalactosaminyltransferase activity |