malate-aspartate shuttle

id: GO:0043490
name: malate-aspartate shuttle
namespace: biological_process
type: go
obsolete: False

Description: The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise malate in the cytosol; this compound is then transported into the mitochondria where it is converted to oxaloacetate using NADH, the oxaloacetate reacts with gluamate to form aspartate, and the aspartate then returns to the cytosol to complete the cycle.

Parent Functions

GO:0006839mitochondrial transport