Organism : Geobacter sulfurreducens | Module List :
heterodisulfide reductase subunit (VIMSS)
Functional Annotations (5)
|Heterodisulfide reductase, subunit B||cog/ cog|
|CoB--CoM heterodisulfide reductase activity||go/ molecular_function|
|Methane metabolism||kegg/ kegg pathway|
|Metabolic pathways||kegg/ kegg pathway|
|Microbial metabolism in diverse environments||kegg/ kegg pathway|
Regulation information for GSU0091(Mouseover regulator name to see its description)
Motif information (de novo identified motifs for modules)
There are 4 motifs predicted.
|Motif Id||e-value||Consensus||Motif Logo|
Functional Enrichment for GSU0091
Module neighborhood information for GSU0091
|Gene||Common Name||Description||Module membership|
|GSU0023||GSU0023||TPR domain protein (NCBI)||111, 214|
|GSU0087||GSU0087||heterodisulfide reductase, iron-sulfur binding subunit, putative (VIMSS)||126, 214|
|GSU0088||GSU0088||heterodisulfide reductase subunit (VIMSS)||169, 214|
|GSU0089||GSU0089||heterodisulfide reductase subunit (VIMSS)||126, 291|
|GSU0090||GSU0090||heterodisulfide reductase subunit (VIMSS)||126, 214|
|GSU0091||GSU0091||heterodisulfide reductase subunit (VIMSS)||126, 214|
|GSU0092||GSU0092||heterodisulfide reductase subunit (NCBI)||127, 214|
|GSU0159||dapA||dihydrodipicolinate synthase (NCBI)||101, 214|
|GSU0213||GSU0213||radical SAM domain protein (NCBI)||126, 323|
|GSU0226||GSU0226||L-lactate permease, putative (VIMSS)||126, 164|
|GSU0526||GSU0526||conserved hypothetical protein (VIMSS)||126, 281|
|GSU0674||hcP-1||hydroxylamine reductase (RefSeq)||16, 214|
|GSU0792||GSU0792||conserved hypothetical protein (VIMSS)||22, 214|
|GSU0825||GSU0825||pirin family protein (VIMSS)||126, 183|
|GSU0860||GSU0860||methylenetetrahydrofolate reductase family protein (VIMSS)||126, 144|
|GSU0862||folD-2||folD bifunctional protein (NCBI)||46, 126|
|GSU0864||GSU0864||conserved hypothetical protein TIGR00251 (VIMSS)||101, 214|
|GSU0865||GSU0865||cell division protein DivIVA, putative (VIMSS)||111, 214|
|GSU1053||GSU1053||sensory box protein (VIMSS)||122, 126|
|GSU1124||coaBC||phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase (NCBI)||126, 295|
|GSU1177||frdA||fumarate reductase, flavoprotein subunit (NCBI)||101, 214|
|GSU1180||ftsH-1||cell division protein FtsH (NCBI)||112, 126|
|GSU1274||GSU1274||radical SAM domain protein (NCBI)||126, 208|
|GSU1298||GSU1298||methyl-accepting chemotaxis protein (VIMSS)||126, 183|
|GSU1322||ccdA||cytochrome c biogenesis protein CcdA (NCBI)||153, 214|
|GSU1334||GSU1334||cytochrome c family protein (NCBI)||137, 214|
|GSU1377||GSU1377||3-hydroxybutyryl-CoA dehydratase (VIMSS)||11, 126|
|GSU1461||pyrF||orotidine 5`-phosphate decarboxylase (NCBI)||126, 233|
|GSU1535||recD||exodeoxyribonuclease V, alpha subunit (NCBI)||126, 336|
|GSU1555||GSU1555||sensory box histidine kinase/response regulator (VIMSS)||153, 214|
|GSU1628||GSU1628||phosphoglycerate kinase/triosephosphate isomerase (VIMSS)||214, 238|
|GSU1761||GSU1761||cytochrome c family protein (VIMSS)||76, 214|
|GSU2047||GSU2047||conserved hypothetical protein (VIMSS)||26, 126|
|GSU2049||argJ||glutamate N-acetyltransferase/amino-acid acetyltransferase (NCBI)||91, 214|
|GSU2050||secA||preprotein translocase, SecA subunit (NCBI)||91, 126|
|GSU2102||GSU2102||pyruvate formate-lyase-activating enzyme, putative (VIMSS)||126, 183|
|GSU2214||cheB-3||protein-glutamate methylesterase (NCBI)||126, 295|
|GSU2222||cheA-2||chemotaxis protein CheA (NCBI)||126, 222|
|GSU2255||GSU2255||conserved hypothetical protein (VIMSS)||28, 214|
|GSU2260||GSU2260||ABC transporter, ATP-binding protein, MsbA family (VIMSS)||28, 214|
|GSU2261||lpxB||lipid A disaccharide synthase (lpxB) (NCBI)||214, 262|
|GSU2262||degT||pleiotropic regulatory protein (NCBI)||28, 214|
|GSU2268||GSU2268||outer membrane protein, putative (VIMSS)||207, 214|
|GSU2269||GSU2269||ABC transporter, ATP-binding protein (VIMSS)||12, 214|
|GSU2272||GSU2272||lipoprotein, putative (VIMSS)||80, 126|
|GSU2731||ferA||polyheme membrane-associated cytochrome c (NCBI)||195, 214|
|GSU2732||GSU2732||cytochrome c family protein (NCBI)||195, 214|
|GSU2733||GSU2733||hypothetical protein (VIMSS)||195, 214|
|GSU2737||GSU2737||polyheme membrane-associated cytochrome c (VIMSS)||195, 214|
|GSU2739||GSU2739||hypothetical protein (VIMSS)||195, 214|
|GSU2879||leuB||3-isopropylmalate dehydrogenase (NCBI)||126, 233|
|GSU3062||GSU3062||radical SAM domain protein (NCBI)||42, 126|
|GSU3210||nadD||nicotinate (nicotinamide) nucleotide adenylyltransferase (NCBI)||160, 214|
|GSU3260||GSU3260||phosphoserine aminotransferase, putative (VIMSS)||35, 126|
|GSU3421||GSU3421||transcriptional regulator, Crp/Fnr family (VIMSS)||126, 164|
Gene Page Help
If the gene is associated with a module(s), its connection to given modules along with other members of that module are shown as network by using CytoscapeWeb. In this view, each green colored circular nodes represent module member genes, purple colored diamonds represent module motifs and red triangles represent regulators. Each node is connected to module (Bicluster) via edges. This representation provides quick overview of all genes, regulators and motifs for modules. It also allows one to see shared genes/motifs/regulators among diferent modules.
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Network inference algorithm uses de novo motif prediction for assigning genes to modules. If there are any motifs identified in the upstream region of a gene, the motif will be shown here. For each motif sequence logo, consensus and e-value will be shown.
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Module Members Tab
Identity of gene members in a module may help to identify potential interactions between different functional modules. Therefore, neighbor genes that share the same module(s) with gene under consideration are shown here. For each memebr, gene name, description and modules that contain it are listed.
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CircVisOur circular module explorer is adapted from visquick originally developed by Dick Kreisberg of Ilya Shmulevich lab at ISB for The Cancer Genome Atlas. We use simplified version of visquick to display distribution of module members and their interactions across the genome. This view provides summary of regulation information for a gene. The main components are;
- 1. All genomic elements for the organism are represented as a circle and each element is separated by black tick marks. In this example chromosome and pDV represent main chromosome and plasmid for D. vulgaris Hildenborough, respectively.
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