TargetScan_49 megaCluster: 9 Residual: 2.58

Summary

Title Cluster Residual Bicluster Conditions Residual Permutation P-Value Var. Exp. First PC Var. Exp. First PC Perm. P-Value
TargetScan_49 9 2.58 6 1 0.723537 0.352

Members

Displaying 1 - 43 of 43
102693 pleckstrin homology-like domain, family B, member 1

Details for - - pleckstrin homology-like domain, family B, member 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 102693

Tuberculist Genomic Region

114874 DDHD domain containing 1

Details for - - DDHD domain containing 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 114874

Tuberculist Genomic Region

12567 cyclin-dependent kinase 4

Details for - - cyclin-dependent kinase 4

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 12567

Tuberculist Genomic Region

12700 cytokine inducible SH2-containing protein

Details for - - cytokine inducible SH2-containing protein

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 12700

Tuberculist Genomic Region

13822 erythrocyte protein band 4.1-like 2

Details for - - erythrocyte protein band 4.1-like 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 13822

Tuberculist Genomic Region

14456 growth arrest specific 6

Details for - - growth arrest specific 6

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 14456

Tuberculist Genomic Region

14457 growth arrest specific 7

Details for RP23-338M9.2 - growth arrest specific 7

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 14457

Tuberculist Genomic Region

15064 major histocompatibility complex, class I-related

Details for - - major histocompatibility complex, class I-related

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 15064

Tuberculist Genomic Region

16001 insulin-like growth factor I receptor

Details for - - insulin-like growth factor I receptor

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 16001

Tuberculist Genomic Region

16438 inositol 1,4,5-trisphosphate receptor 1

Details for - - inositol 1,4,5-trisphosphate receptor 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 16438

Tuberculist Genomic Region

16443 intersectin 1 (SH3 domain protein 1A)

Details for - - intersectin 1 (SH3 domain protein 1A)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 16443

Tuberculist Genomic Region

18034 nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100

Details for - - nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 18034

Tuberculist Genomic Region

192654 phospholipase A2, group XV

Details for - - phospholipase A2, group XV

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 192654

Tuberculist Genomic Region

20111 ribosomal protein S6 kinase polypeptide 1

Details for RP23-256C7.2 - ribosomal protein S6 kinase polypeptide 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 20111

Tuberculist Genomic Region

208846 dishevelled associated activator of morphogenesis 1

Details for - - dishevelled associated activator of morphogenesis 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 208846

Tuberculist Genomic Region

224796 chloride intracellular channel 5

Details for - - chloride intracellular channel 5

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 224796

Tuberculist Genomic Region

232984 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8

Details for - - UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 232984

Tuberculist Genomic Region

233552 glycerophosphodiester phosphodiesterase domain containing 5

Details for - - glycerophosphodiester phosphodiesterase domain containing 5

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 233552

Tuberculist Genomic Region

234911 matrix metallopeptidase 27

Details for - - matrix metallopeptidase 27

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 234911

Tuberculist Genomic Region

235627 neurobeachin-like 2

Details for - - neurobeachin-like 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 235627

Tuberculist Genomic Region

26921 mitogen-activated protein kinase kinase kinase kinase 4

Details for - - mitogen-activated protein kinase kinase kinase kinase 4

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 26921

Tuberculist Genomic Region

27029 N-sulfoglucosamine sulfohydrolase (sulfamidase)

Details for RP23-25M3.2 - N-sulfoglucosamine sulfohydrolase (sulfamidase)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 27029

Tuberculist Genomic Region

29869 unc-51 like kinase 2

Details for RP23-278F12.5 - unc-51 like kinase 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 29869

Tuberculist Genomic Region

331004 solute carrier family 9 (sodium/hydrogen exchanger), member 9

Details for - - solute carrier family 9 (sodium/hydrogen exchanger), member 9

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 331004

Tuberculist Genomic Region

381511 pyruvate dehyrogenase phosphatase catalytic subunit 1

Details for RP23-203A12.1 - pyruvate dehyrogenase phosphatase catalytic subunit 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 381511

Tuberculist Genomic Region

52614 EGF-like module containing, mucin-like, hormone receptor-like sequence 4

Details for - - EGF-like module containing, mucin-like, hormone receptor-like sequence 4

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 52614

Tuberculist Genomic Region

56221 chemokine (C-C motif) ligand 24

Details for - - chemokine (C-C motif) ligand 24

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 56221

Tuberculist Genomic Region

634650 guanylate binding protein 11

Details for - - guanylate binding protein 11

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 634650

Tuberculist Genomic Region

69941 RIKEN cDNA 2810408I11 gene

Details for - - RIKEN cDNA 2810408I11 gene

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 69941

Tuberculist Genomic Region

70021 5'-nucleotidase domain containing 2

Details for - - 5'-nucleotidase domain containing 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 70021

Tuberculist Genomic Region

75146 transmembrane protein 180

Details for - - transmembrane protein 180

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 75146

Tuberculist Genomic Region

76267 fatty acid desaturase 1

Details for - - fatty acid desaturase 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 76267

Tuberculist Genomic Region

84035 kringle containing transmembrane protein 1

Details for RP23-293J16.1 - kringle containing transmembrane protein 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 84035

Tuberculist Genomic Region

12769 chemokine (C-C motif) receptor 9

Details for - - chemokine (C-C motif) receptor 9

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 12769

Tuberculist Genomic Region

70123 RIKEN cDNA 2210013O21 gene

Details for - - RIKEN cDNA 2210013O21 gene

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 70123

Tuberculist Genomic Region

71769 Bardet-Biedl syndrome 10 (human)

Details for - - Bardet-Biedl syndrome 10 (human)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 71769

Tuberculist Genomic Region

17119 MAX dimerization protein 1

Details for - - MAX dimerization protein 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17119

Tuberculist Genomic Region

217946 cell division cycle associated 7 like

Details for - - cell division cycle associated 7 like

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 217946

Tuberculist Genomic Region

333433 glycerol-3-phosphate dehydrogenase 1-like

Details for - - glycerol-3-phosphate dehydrogenase 1-like

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 333433

Tuberculist Genomic Region

66881 prenylcysteine oxidase 1

Details for - - prenylcysteine oxidase 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 66881

Tuberculist Genomic Region

72674 adiponectin receptor 1

Details for - - adiponectin receptor 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 72674

Tuberculist Genomic Region

17064 CD93 antigen

Details for RP23-70N3.4 - CD93 antigen

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17064

Tuberculist Genomic Region

67245 pellino 1

Details for RP23-93O11.1 - pellino 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 67245

Tuberculist Genomic Region

TFBS DB TF

TFs percTargets pValue
EWSR1-FLI1_MA0149.1, V_EWSR1FLI1_01_M02252 0.857143, 0.857143 0.00000187

GO Terms

Displaying 1 - 1 of 1
GO Terms
NA

Upstream MEME Motif

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif2 E-Value Motif2 Consensus Motif2 Matches
0.000000016 SCTTTTYTTTT NA 0.00039 KGKGGGNGGGGM SP1_MA0079.2, Klf4_MA0039.2, V$SP4_Q5_M01273, V$SP1_Q4_01_M00932, V$SP1_Q2_01_M00933, V$SP1_Q6_M00196, V$SP1_03_M02281, V$ZFP281_01_M01597, V$SP1_Q6_01_M00931, V$GKLF_02_M01588, V$SP1_02_M01303, V$KLF7_03_M02773, V$ZFP281_04_M02831, V$CKROX_Q2_M01175, V$GC_01_M00255, V$ZBP89_Q4_M01816, V$MAZ_Q6_01_M02023, V$MAZR_01_M00491, V$UF1H3BETA_Q6_M01068, V$ZNF219_01_M01122, V$MAZ_Q6_M00649, V$SP4_03_M02810, V$ZFP740_03_M02834, V$SP1SP3_Q4_M01219, V$SMAD4_04_M02898, V$EGR1_Q6_M01873, V$KROX_Q6_M00982, V$EGR1_06_M02744, V$CACD_01_M01113, V$BCL6B_04_M02844, V$WT1_Q6_01_M02036, V$SP1_01_M00008, V$CACBINDINGPROTEIN_Q6_M00720, V$EGR_Q6_M00807, V$EKLF_Q5_M01874, V$E2F3_Q6_M02089, V$SP2_01_M01783, V$FKLF_Q5_M01837, V$CACCCBINDINGFACTOR_Q6_M00721, V$WT1_Q6_M01118, V$ZFP410_04_M02936, V$GLI3_Q5_01_M01657, V$ASCL2_04_M02841, V$EGR2_Q6_M02092, V$SOX14_04_M02901, V$KLF15_Q2_M01714, V$CHCH_01_M00986, V$ETF_Q6_M00695, V$ZNF515_01_M01231, V$MZF1_02_M00084, V$MZF1_01_M00083, V$EGR1_02_M01972, Klf7.1, Zfp281.2, Sp4.1, Zfp740.1, Smad3.1, Egr1.1, Bcl6b.2, Zfp410.1, Sox13.2, Ascl2.2, Zif268.1, Egr1.2, KLF16_C2H2_DBD_monomeric_11_1, ZNF740_C2H2_full_monomeric_10_1, SP8_C2H2_DBD_monomeric_12_1, SP1_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, SP4_C2H2_full_monomeric_17_1, KLF14_C2H2_DBD_monomeric_14_1, Klf12_C2H2_DBD_monomeric_15_1, Zfp740_C2H2_DBD_monomeric_10_1, Egr1_C2H2_mouse-DBD_mutant_DBD_monomeric_16_1

Upstream Weeder Motif

Motif1 Score Motif1 Consensus Motif1 Matches Motif2 Score Motif2 Consensus Motif2 Matches
1.03 CGCGGA NA 1.12 CGGGANCG NA

3p UTR Weeder

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif1 Model Motif2 E-Value Motif2 Consensus Motif2 Matches Motif2 Model
0.56 CGGTCG NA NA 0.61 CGNGGACG NA NA

3p UTR PITA

miRNAs percTargets pValue
mmu-miR-741 0.805556 0.00000067

3p UTR TargetScan

miRNAs percTargets pValue
mmu-miR-698 0.342105 0.00000205

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