|  |  | B-1 B cell homeostasisprotease bindingresponse to molecule of bacterial originmarginal zone B cell differentiationnegative regulation of granuloma formationregulation of germinal center formationregulation of immunoglobulin productionnegative regulation of chronic inflammatory responseDNA bindingcatalytic activityubiquitin thiolesterase activityubiquitin-protein ligase activityubiquitin-specific protease activityprotein bindingnucleuscytoplasmlysosomecentrosomeproteolysisapoptotic processinflammatory responsemetabolic processpeptidase activitycysteine-type peptidase activityzinc ion bindingresponse to woundingnegative regulation of autophagyprotein deubiquitinationhydrolase activityligase activitykinase bindingnegative regulation of protein ubiquitinationnegative regulation of NF-kappaB transcription factor activityresponse to muramyl dipeptidenegative regulation of interleukin-1 beta productionnegative regulation of interleukin-2 productionnegative regulation of interleukin-6 productionnegative regulation of tumor necrosis factor productionnegative regulation of heterotypic cell-cell adhesionnegative regulation of toll-like receptor 3 signaling pathwaynegative regulation of toll-like receptor 5 signaling pathwayprotein K11-linked deubiquitinationnegative regulation of I-kappaB kinase/NF-kappaB signalingubiquitin bindingprotein self-associationregulation of innate immune responsepositive regulation of protein catabolic processnegative regulation of cyclin-dependent protein serine/threonine kinase activitynegative regulation of innate immune responsemetal ion bindingnegative regulation of smooth muscle cell proliferationnegative regulation of inflammatory responsenegative regulation of B cell activationnegative regulation of cell deathcellular response to hydrogen peroxidenegative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathwaynegative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathwayprotein K63-linked deubiquitinationprotein K48-linked ubiquitinationprotein K48-linked deubiquitinationcellular response to lipopolysaccharidetolerance induction to lipopolysaccharidenegative regulation of extrinsic apoptotic signaling pathway via death domain receptorspositive regulation of hepatocyte proliferationnegative regulation of CD40 signaling pathwaynegative regulation of endothelial cell apoptotic process
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