PITA_73 megaCluster: 1 Residual: 0.22 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_73	1	0.22	13	0	0.869835	0

Members

Displaying 1 - 30 of 30

11812 apolipoprotein C-I Details for - - apolipoprotein C-I GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11812 Tuberculist Genomic Region	15894 intercellular adhesion molecule 1 Details for - - intercellular adhesion molecule 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15894 Tuberculist Genomic Region
17135 v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian) Details for - - v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17135 Tuberculist Genomic Region	19730 ral guanine nucleotide dissociation stimulator Details for RP23-430H1.6 - ral guanine nucleotide dissociation stimulator GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19730 Tuberculist Genomic Region
20557 schlafen 3 Details for RP23-381B19.1 - schlafen 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20557 Tuberculist Genomic Region	207683 immunoglobulin superfamily, member 11 Details for RP23-131M7.1 - immunoglobulin superfamily, member 11 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 207683 Tuberculist Genomic Region
208266 DOT1-like, histone H3 methyltransferase (S. cerevisiae) Details for - - DOT1-like, histone H3 methyltransferase (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 208266 Tuberculist Genomic Region	22337 vitamin D receptor Details for - - vitamin D receptor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22337 Tuberculist Genomic Region
228608 spermine oxidase Details for RP23-442K11.1 - spermine oxidase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 228608 Tuberculist Genomic Region	230738 zinc finger CCCH type containing 12A Details for RP23-325M14.9 - zinc finger CCCH type containing 12A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 230738 Tuberculist Genomic Region
320189 RIKEN cDNA 9430076C15 gene Details for - - RIKEN cDNA 9430076C15 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 320189 Tuberculist Genomic Region	320790 chromodomain helicase DNA binding protein 7 Details for RP23-464N23.1 - chromodomain helicase DNA binding protein 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 320790 Tuberculist Genomic Region
338523 lysine (K)-specific demethylase 7A Details for - - lysine (K)-specific demethylase 7A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 338523 Tuberculist Genomic Region	621976 transmembrane protein 170B Details for - - transmembrane protein 170B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 621976 Tuberculist Genomic Region
628596 eukaryotic translation initiation factor 1 pseudogene Details for - - eukaryotic translation initiation factor 1 pseudogene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 628596 Tuberculist Genomic Region	72504 TAF4B RNA polymerase II, TATA box binding protein (TBP)-associated factor Details for - - TAF4B RNA polymerase II, TATA box binding protein (TBP)-associated factor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72504 Tuberculist Genomic Region
76650 sulfiredoxin 1 homolog (S. cerevisiae) Details for - - sulfiredoxin 1 homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76650 Tuberculist Genomic Region	14191 Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog Details for RP23-125F21.1 - Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14191 Tuberculist Genomic Region
16001 insulin-like growth factor I receptor Details for - - insulin-like growth factor I receptor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16001 Tuberculist Genomic Region	16180 interleukin 1 receptor accessory protein Details for - - interleukin 1 receptor accessory protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16180 Tuberculist Genomic Region
16477 jun B proto-oncogene Details for - - jun B proto-oncogene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16477 Tuberculist Genomic Region	16648 karyopherin (importin) alpha 3 Details for - - karyopherin (importin) alpha 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16648 Tuberculist Genomic Region
16816 lecithin cholesterol acyltransferase Details for - - lecithin cholesterol acyltransferase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16816 Tuberculist Genomic Region	17355 AF4/FMR2 family, member 1 Details for AL731554.2 - AF4/FMR2 family, member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17355 Tuberculist Genomic Region
19106 eukaryotic translation initiation factor 2-alpha kinase 2 Details for - - eukaryotic translation initiation factor 2-alpha kinase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19106 Tuberculist Genomic Region	26570 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 Details for - - solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26570 Tuberculist Genomic Region
56715 RAB guanine nucleotide exchange factor (GEF) 1 Details for - - RAB guanine nucleotide exchange factor (GEF) 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56715 Tuberculist Genomic Region	667281 histocompatibility 60b Details for - - histocompatibility 60b GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 667281 Tuberculist Genomic Region
21929 tumor necrosis factor, alpha-induced protein 3 Details for - - tumor necrosis factor, alpha-induced protein 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21929 Tuberculist Genomic Region	23921 SH2B adaptor protein 2 Details for - - SH2B adaptor protein 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 23921 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
Zfp281.2, SP1_MA0079.2, V_SP1_03_M02281, V_UF1H3BETA_Q6_M01068, V_MAZ_Q6_01_M02023, V_CACBINDINGPROTEIN_Q6_M00720, V_ZFP281_01_M01597, V_ZFP281_04_M02831, V_SP1_Q2_01_M00933	1, 1, 1, 1, 1, 1, 1, 1, 1	0

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.49	GSGGNRGCGGGG	SP1_MA0079.2, V$RNF96_01_M01199, V$SP1_03_M02281, V$EGR1_Q6_M01873, V$ZFP281_01_M01597, V$ETF_Q6_M00695, V$SP1SP3_Q4_M01219, V$KROX_Q6_M00982, V$UF1H3BETA_Q6_M01068, V$SP1_Q6_M00196, V$SP4_Q5_M01273, V$SP1_02_M01303, V$SP1_Q2_01_M00933, V$EGR1_06_M02744, V$ZNF219_01_M01122, V$EGR_Q6_M00807, V$ZFP281_04_M02831, Egr1.1, Zfp281.2, Smad3.1, Zfp410.1, Bcl6b.2, Sp4.1	1.8	AAAAAAAMAGAA	V$IRF_Q6_01_M00972, V$IRF1_Q6_M00747

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.36	GCTCCG	NA	1.62	CGCNCCGG	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.58	GTTACG	NA	NA	0.76	NGTTACGG	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
mmu-miR-412	0.714286	0.0000121

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-376a	0.217391	0.000000879

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