TargetScan_1 megaCluster: 3 Residual: 0.17 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_1	3	0.17	15	0	0.939052	0

Members

Displaying 1 - 23 of 23

100715 PAP associated domain containing 4 Details for - - PAP associated domain containing 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100715 Tuberculist Genomic Region	12051 B cell leukemia/lymphoma 3 Details for - - B cell leukemia/lymphoma 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12051 Tuberculist Genomic Region
121021 chondroitin sulfate proteoglycan 4 Details for - - chondroitin sulfate proteoglycan 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 121021 Tuberculist Genomic Region	12153 bone morphogenetic protein 1 Details for - - bone morphogenetic protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12153 Tuberculist Genomic Region
12874 carboxypeptidase D Details for RP23-396O3.1 - carboxypeptidase D GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12874 Tuberculist Genomic Region	14081 acyl-CoA synthetase long-chain family member 1 Details for - - acyl-CoA synthetase long-chain family member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14081 Tuberculist Genomic Region
14747 chemokine-like receptor 1 Details for - - chemokine-like receptor 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14747 Tuberculist Genomic Region	16543 MyoD family inhibitor domain containing Details for - - MyoD family inhibitor domain containing GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16543 Tuberculist Genomic Region
17387 matrix metallopeptidase 14 (membrane-inserted) Details for - - matrix metallopeptidase 14 (membrane-inserted) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17387 Tuberculist Genomic Region	18227 nuclear receptor subfamily 4, group A, member 2 Details for RP23-271B15.1 - nuclear receptor subfamily 4, group A, member 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18227 Tuberculist Genomic Region
18788 serine (or cysteine) peptidase inhibitor, clade B, member 2 Details for - - serine (or cysteine) peptidase inhibitor, clade B, member 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18788 Tuberculist Genomic Region	209630 FERM domain containing 4A Details for RP23-198D21.2 - FERM domain containing 4A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 209630 Tuberculist Genomic Region
21923 tenascin C Details for RP24-144L11.1 - tenascin C GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21923 Tuberculist Genomic Region	22165 TXK tyrosine kinase Details for - - TXK tyrosine kinase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22165 Tuberculist Genomic Region
234839 piezo-type mechanosensitive ion channel component 1 Details for - - piezo-type mechanosensitive ion channel component 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 234839 Tuberculist Genomic Region	30940 ubiquitin specific peptidase 25 Details for - - ubiquitin specific peptidase 25 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 30940 Tuberculist Genomic Region
432486 N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits Details for - - N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 432486 Tuberculist Genomic Region	54004 diaphanous homolog 2 (Drosophila) Details for - - diaphanous homolog 2 (Drosophila) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 54004 Tuberculist Genomic Region
60533 CD274 antigen Details for - - CD274 antigen GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 60533 Tuberculist Genomic Region	667597 cDNA sequence BC023105 Details for - - cDNA sequence BC023105 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 667597 Tuberculist Genomic Region
67399 PDZ and LIM domain 7 Details for RP23-211O9.2 - PDZ and LIM domain 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67399 Tuberculist Genomic Region	98999 zinc finger, NFX1-type containing 1 Details for RP23-19L12.5 - zinc finger, NFX1-type containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 98999 Tuberculist Genomic Region
16402 integrin alpha 5 (fibronectin receptor alpha) Details for - - integrin alpha 5 (fibronectin receptor alpha) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16402 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_RSRFC4_Q2_M00407	0.272727	0.00000109

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.0086	ARAAAARAAAAA	NA	0.042	SCYCCGCCCCC	SP1_MA0079.2, Klf4_MA0039.2, V$SP4_Q5_M01273, V$SP1_Q6_M00196, V$SP1_Q4_01_M00932, V$SP1_Q6_01_M00931, V$SP1_Q2_01_M00933, V$SP1_03_M02281, V$ZFP281_01_M01597, V$GC_01_M00255, V$EGR1_Q6_M01873, V$SP4_03_M02810, V$EGR1_06_M02744, V$KROX_Q6_M00982, V$UF1H3BETA_Q6_M01068, V$ZBP89_Q4_M01816, V$SP1_02_M01303, V$KLF7_03_M02773, V$SP1SP3_Q4_M01219, V$ZNF219_01_M01122, V$ZFP281_04_M02831, V$GKLF_02_M01588, V$MAZ_Q6_01_M02023, V$MAZR_01_M00491, V$WT1_Q6_01_M02036, V$CKROX_Q2_M01175, V$FPM315_01_M01587, V$ETF_Q6_M00695, V$SP2_01_M01783, V$BCL6B_04_M02844, V$EGR_Q6_M00807, V$SMAD4_04_M02898, V$SP1_01_M00008, V$EGR1_02_M01972, V$ZFP740_03_M02834, V$CACBINDINGPROTEIN_Q6_M00720, V$FKLF_Q5_M01837, V$CACD_01_M01113, V$E2F3_Q6_M02089, V$ZFP410_04_M02936, V$MAZ_Q6_M00649, V$NGFIC_01_M00244, V$CTCF_01_M01200, V$EGR1_01_M00243, V$BTEB3_Q5_M01865, V$EKLF_Q5_M01874, V$GKLF_Q4_M01835, Sp4.1, Egr1.1, Klf7.1, Zfp281.2, Zif268.1, Smad3.1, Bcl6b.2, Zfp740.1, Zfp410.1, Klf7.2, KLF16_C2H2_DBD_monomeric_11_1, SP1_C2H2_DBD_monomeric_11_1, SP4_C2H2_full_monomeric_17_1, SP3_C2H2_DBD_monomeric_11_1, SP8_C2H2_DBD_monomeric_12_1, Egr1_C2H2_mouse-DBD_mutant_DBD_monomeric_16_1, KLF14_C2H2_DBD_monomeric_14_1, ZNF740_C2H2_full_monomeric_10_1, EGR2_C2H2_full_monomeric_15_1, Klf12_C2H2_DBD_monomeric_15_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.34	CGCGGA	NA	1.4	CCNCTCCG	Egr1.2

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.8	AANGGA	NA	NA	0.91	ACCCTCST	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-2137	0.157895	0.0000103

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