TargetScan_180 megaCluster: 9 Residual: 0.73

Summary

Title Cluster Residual Bicluster Conditions Residual Permutation P-Value Var. Exp. First PC Var. Exp. First PC Perm. P-Value
TargetScan_180 9 0.73 6 0.842 0.624668 0.997

Members

Displaying 1 - 51 of 51
104799 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog

Details for - - VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 104799

Tuberculist Genomic Region

15926 isocitrate dehydrogenase 1 (NADP+), soluble

Details for - - isocitrate dehydrogenase 1 (NADP+), soluble

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 15926

Tuberculist Genomic Region

53881 solute carrier family 5 (inositol transporters), member 3

Details for - - solute carrier family 5 (inositol transporters), member 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 53881

Tuberculist Genomic Region

60534 Fanconi anemia, complementation group G

Details for RP23-124L1.6 - Fanconi anemia, complementation group G

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 60534

Tuberculist Genomic Region

66775 protein tyrosine phosphatase-like A domain containing 2

Details for - - protein tyrosine phosphatase-like A domain containing 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 66775

Tuberculist Genomic Region

71207 nudix (nucleoside diphosphate linked moiety X)-type motif 4

Details for - - nudix (nucleoside diphosphate linked moiety X)-type motif 4

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 71207

Tuberculist Genomic Region

71966 NFKB inhibitor interacting Ras-like protein 2

Details for RP23-390D17.2 - NFKB inhibitor interacting Ras-like protein 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 71966

Tuberculist Genomic Region

100503037 predicted gene, 19520

Details for - - predicted gene, 19520

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 100503037

Tuberculist Genomic Region

107375 solute carrier family 25, member 45

Details for - - solute carrier family 25, member 45

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 107375

Tuberculist Genomic Region

110279 breakpoint cluster region

Details for - - breakpoint cluster region

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 110279

Tuberculist Genomic Region

11515 adenylate cyclase 9

Details for - - adenylate cyclase 9

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 11515

Tuberculist Genomic Region

116914 solute carrier family 19 (thiamine transporter), member 2

Details for - - solute carrier family 19 (thiamine transporter), member 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 116914

Tuberculist Genomic Region

12495 ectonucleoside triphosphate diphosphohydrolase 1

Details for - - ectonucleoside triphosphate diphosphohydrolase 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 12495

Tuberculist Genomic Region

12522 CD83 antigen

Details for - - CD83 antigen

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 12522

Tuberculist Genomic Region

13555 E2F transcription factor 1

Details for RP23-109C16.5 - E2F transcription factor 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 13555

Tuberculist Genomic Region

14865 glutathione S-transferase, mu 4

Details for RP23-214E3.8 - glutathione S-transferase, mu 4

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 14865

Tuberculist Genomic Region

15170 protein tyrosine phosphatase, non-receptor type 6

Details for - - protein tyrosine phosphatase, non-receptor type 6

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 15170

Tuberculist Genomic Region

16438 inositol 1,4,5-trisphosphate receptor 1

Details for - - inositol 1,4,5-trisphosphate receptor 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 16438

Tuberculist Genomic Region

17064 CD93 antigen

Details for RP23-70N3.4 - CD93 antigen

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17064

Tuberculist Genomic Region

17686 mutS homolog 3 (E. coli)

Details for - - mutS homolog 3 (E. coli)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17686

Tuberculist Genomic Region

195046 NLR family, pyrin domain containing 1A

Details for DN-393H17.9 - NLR family, pyrin domain containing 1A

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 195046

Tuberculist Genomic Region

21844 T cell lymphoma invasion and metastasis 1

Details for - - T cell lymphoma invasion and metastasis 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 21844

Tuberculist Genomic Region

225049 tetratricopeptide repeat domain 7

Details for - - tetratricopeptide repeat domain 7

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 225049

Tuberculist Genomic Region

226856 lysophosphatidylglycerol acyltransferase 1

Details for - - lysophosphatidylglycerol acyltransferase 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 226856

Tuberculist Genomic Region

233064 WD repeat domain 62

Details for - - WD repeat domain 62

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 233064

Tuberculist Genomic Region

234353 pleckstrin and Sec7 domain containing 3

Details for - - pleckstrin and Sec7 domain containing 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 234353

Tuberculist Genomic Region

234854 cyclin-dependent kinase 10

Details for - - cyclin-dependent kinase 10

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 234854

Tuberculist Genomic Region

23854 differentially expressed in FDCP 8

Details for - - differentially expressed in FDCP 8

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 23854

Tuberculist Genomic Region

239217 potassium channel tetramerisation domain containing 12

Details for - - potassium channel tetramerisation domain containing 12

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 239217

Tuberculist Genomic Region

319660 alkylglycerol monooxygenase

Details for - - alkylglycerol monooxygenase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 319660

Tuberculist Genomic Region

353346 G protein-coupled receptor 141

Details for - - G protein-coupled receptor 141

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 353346

Tuberculist Genomic Region

67547 solute carrier family 39 (metal ion transporter), member 8

Details for - - solute carrier family 39 (metal ion transporter), member 8

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 67547

Tuberculist Genomic Region

67623 transmembrane 7 superfamily member 3

Details for RP23-158O11.3 - transmembrane 7 superfamily member 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 67623

Tuberculist Genomic Region

70510 ring finger protein 167

Details for DN-183N8.14-002 - ring finger protein 167

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 70510

Tuberculist Genomic Region

72565 uveal autoantigen with coiled-coil domains and ankyrin repeats

Details for - - uveal autoantigen with coiled-coil domains and ankyrin repeats

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 72565

Tuberculist Genomic Region

72836 protection of telomeres 1B

Details for - - protection of telomeres 1B

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 72836

Tuberculist Genomic Region

78771 multiple C2 domains, transmembrane 1

Details for - - multiple C2 domains, transmembrane 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 78771

Tuberculist Genomic Region

110796 teashirt zinc finger family member 1

Details for - - teashirt zinc finger family member 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 110796

Tuberculist Genomic Region

218215 ring finger protein 144B

Details for - - ring finger protein 144B

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 218215

Tuberculist Genomic Region

252972 two pore channel 1

Details for - - two pore channel 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 252972

Tuberculist Genomic Region

76429 phospholysine phosphohistidine inorganic pyrophosphate phosphatase

Details for - - phospholysine phosphohistidine inorganic pyrophosphate phosphatase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 76429

Tuberculist Genomic Region

103140 glutathione S-transferase, theta 3

Details for - - glutathione S-transferase, theta 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 103140

Tuberculist Genomic Region

105727 solute carrier family 38, member 1

Details for - - solute carrier family 38, member 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 105727

Tuberculist Genomic Region

17346 MAP kinase-interacting serine/threonine kinase 1

Details for RP23-374N19.2 - MAP kinase-interacting serine/threonine kinase 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17346

Tuberculist Genomic Region

26416 mitogen-activated protein kinase 14

Details for RP24-137E7.1 - mitogen-activated protein kinase 14

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 26416

Tuberculist Genomic Region

66257 nicolin 1

Details for - - nicolin 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 66257

Tuberculist Genomic Region

97998 DEP domain containing MTOR-interacting protein

Details for - - DEP domain containing MTOR-interacting protein

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 97998

Tuberculist Genomic Region

12846 catechol-O-methyltransferase

Details for - - catechol-O-methyltransferase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 12846

Tuberculist Genomic Region

14247 Friend leukemia integration 1

Details for - - Friend leukemia integration 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 14247

Tuberculist Genomic Region

224014 FYVE, RhoGEF and PH domain containing 4

Details for - - FYVE, RhoGEF and PH domain containing 4

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 224014

Tuberculist Genomic Region

68318 anterior pharynx defective 1c homolog (C. elegans)

Details for - - anterior pharynx defective 1c homolog (C. elegans)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 68318

Tuberculist Genomic Region

TFBS DB TF

TFs percTargets pValue
NA

GO Terms

Displaying 1 - 1 of 1
GO Terms
NA

Upstream MEME Motif

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif2 E-Value Motif2 Consensus Motif2 Matches
0.0000000000000013 AAAAAMAAAARA NA 3.6 TTTTTGWGTNA NA

Upstream Weeder Motif

Motif1 Score Motif1 Consensus Motif1 Matches Motif2 Score Motif2 Consensus Motif2 Matches
0.93 CGCGAT NA 0.93 TCGCGNCC NA

3p UTR Weeder

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif1 Model Motif2 E-Value Motif2 Consensus Motif2 Matches Motif2 Model
0.51 ACGCGG NA NA 0.54 TGTACCNT NA NA

3p UTR PITA

miRNAs percTargets pValue
mmu-miR-669e 0.681818 0.00000138

3p UTR TargetScan

miRNAs percTargets pValue
mmu-miR-153 0.361702 0.00000169

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