PITA_132 megaCluster: 8 Residual: 0.30 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_132	8	0.30	15	0	0.84253	0

Members

Displaying 1 - 38 of 38

170439 ELOVL family member 6, elongation of long chain fatty acids (yeast) Details for - - ELOVL family member 6, elongation of long chain fatty acids (yeast) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 170439 Tuberculist Genomic Region	17686 mutS homolog 3 (E. coli) Details for - - mutS homolog 3 (E. coli) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17686 Tuberculist Genomic Region
18479 p21 protein (Cdc42/Rac)-activated kinase 1 Details for - - p21 protein (Cdc42/Rac)-activated kinase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18479 Tuberculist Genomic Region	215201 TRM2 tRNA methyltransferase 2B Details for RP23-162B19.2 - TRM2 tRNA methyltransferase 2B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 215201 Tuberculist Genomic Region
217653 MIS18 binding protein 1 Details for - - MIS18 binding protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 217653 Tuberculist Genomic Region	226744 consortin, connexin sorting protein Details for - - consortin, connexin sorting protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 226744 Tuberculist Genomic Region
230101 glucosidase beta 2 Details for RP23-191F22.2 - glucosidase beta 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 230101 Tuberculist Genomic Region	26382 FYVE, RhoGEF and PH domain containing 2 Details for - - FYVE, RhoGEF and PH domain containing 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26382 Tuberculist Genomic Region
26879 UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1 Details for - - UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26879 Tuberculist Genomic Region	269587 erythrocyte protein band 4.1 Details for RP23-13A13.5 - erythrocyte protein band 4.1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 269587 Tuberculist Genomic Region
408022 primase and polymerase (DNA-directed) Details for - - primase and polymerase (DNA-directed) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 408022 Tuberculist Genomic Region	66939 alpha- and gamma-adaptin binding protein Details for - - alpha- and gamma-adaptin binding protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66939 Tuberculist Genomic Region
68366 transmembrane protein 129 Details for - - transmembrane protein 129 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68366 Tuberculist Genomic Region	77938 family with sequence similarity 53, member B Details for - - family with sequence similarity 53, member B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 77938 Tuberculist Genomic Region
106795 transcription factor 19 Details for - - transcription factor 19 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 106795 Tuberculist Genomic Region	13830 stomatin Details for RP23-186B18.3 - stomatin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13830 Tuberculist Genomic Region
13852 syntaxin 2 Details for - - syntaxin 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13852 Tuberculist Genomic Region	14247 Friend leukemia integration 1 Details for - - Friend leukemia integration 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14247 Tuberculist Genomic Region
16443 intersectin 1 (SH3 domain protein 1A) Details for - - intersectin 1 (SH3 domain protein 1A) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16443 Tuberculist Genomic Region	17216 minichromosome maintenance deficient 2 mitotin (S. cerevisiae) Details for - - minichromosome maintenance deficient 2 mitotin (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17216 Tuberculist Genomic Region
17979 nuclear receptor coactivator 3 Details for RP23-120P1.1 - nuclear receptor coactivator 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17979 Tuberculist Genomic Region	18010 neuraminidase 1 Details for - - neuraminidase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18010 Tuberculist Genomic Region
209131 sorting nexin family member 30 Details for RP23-451K12.1 - sorting nexin family member 30 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 209131 Tuberculist Genomic Region	217666 L-2-hydroxyglutarate dehydrogenase Details for - - L-2-hydroxyglutarate dehydrogenase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 217666 Tuberculist Genomic Region
219072 HAUS augmin-like complex, subunit 4 Details for - - HAUS augmin-like complex, subunit 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 219072 Tuberculist Genomic Region	224014 FYVE, RhoGEF and PH domain containing 4 Details for - - FYVE, RhoGEF and PH domain containing 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 224014 Tuberculist Genomic Region
231801 ArfGAP with FG repeats 2 Details for - - ArfGAP with FG repeats 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 231801 Tuberculist Genomic Region	241303 family with sequence similarity 78, member A Details for RP23-55I14.8 - family with sequence similarity 78, member A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 241303 Tuberculist Genomic Region
26412 mitogen-activated protein kinase kinase kinase kinase 2 Details for - - mitogen-activated protein kinase kinase kinase kinase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26412 Tuberculist Genomic Region	27221 chromatin assembly factor 1, subunit A (p150) Details for - - chromatin assembly factor 1, subunit A (p150) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 27221 Tuberculist Genomic Region
56187 Rab geranylgeranyl transferase, a subunit Details for - - Rab geranylgeranyl transferase, a subunit GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56187 Tuberculist Genomic Region	60534 Fanconi anemia, complementation group G Details for RP23-124L1.6 - Fanconi anemia, complementation group G GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 60534 Tuberculist Genomic Region
74772 ATPase type 13A2 Details for RP23-183L1.4 - ATPase type 13A2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74772 Tuberculist Genomic Region	20460 Scl/Tal1 interrupting locus Details for RP23-295C20.5 - Scl/Tal1 interrupting locus GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20460 Tuberculist Genomic Region
229521 synaptotagmin XI Details for - - synaptotagmin XI GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 229521 Tuberculist Genomic Region	70719 histocompatibility (minor) HA-1 Details for - - histocompatibility (minor) HA-1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70719 Tuberculist Genomic Region
235559 topoisomerase (DNA) II binding protein 1 Details for - - topoisomerase (DNA) II binding protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 235559 Tuberculist Genomic Region	70472 ATPase family, AAA domain containing 2 Details for - - ATPase family, AAA domain containing 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70472 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
CTCF_C2H2_full_monomeric_17_1	0.789474	0.0000000606

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.000000024	AARAAAWAWAAW	NA	0.0000000015	MGGCCCCGCCCC	SP1_MA0079.2, Klf4_MA0039.2, SP1_MA0079.1, V$SP1_Q6_01_M00931, V$GC_01_M00255, V$SP1_Q6_M00196, V$SP1_Q4_01_M00932, V$SP4_Q5_M01273, V$SP1_Q2_01_M00933, V$SP1_02_M01303, V$KLF7_03_M02773, V$SP1_03_M02281, V$SP4_03_M02810, V$MAZR_01_M00491, V$ZFP281_01_M01597, V$UF1H3BETA_Q6_M01068, V$SP1_01_M00008, V$GKLF_02_M01588, V$SMAD4_04_M02898, V$SP2_01_M01783, V$KROX_Q6_M00982, V$E2F3_Q6_M02089, V$BCL6B_04_M02844, V$EGR1_Q6_M01873, V$CKROX_Q2_M01175, V$MAZ_Q6_01_M02023, V$EGR1_06_M02744, V$ZFP410_04_M02936, V$ZBP89_Q4_M01816, V$MAZ_Q6_M00649, V$ZFP281_04_M02831, V$ZFP740_03_M02834, V$SP4_04_M02914, V$CACD_01_M01113, V$WT1_Q6_01_M02036, V$ZNF219_01_M01122, V$CNOT3_01_M01253, Klf7.1, Sp4.1, Smad3.1, Bcl6b.2, Egr1.1, Zfp410.1, Zfp281.2, Zfp740.1, Sp4.2, Zif268.1, Klf7.2, Ascl2.2, SP4_C2H2_full_monomeric_17_1, SP1_C2H2_DBD_monomeric_11_1, KLF16_C2H2_DBD_monomeric_11_1, KLF14_C2H2_DBD_monomeric_14_1, KLF13_C2H2_full_monomeric_18_1, SP3_C2H2_DBD_monomeric_11_1, Klf12_C2H2_DBD_monomeric_15_1, SP8_C2H2_DBD_monomeric_12_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.17	TCGGCG	E2F3.2, E2F2.2	1.51	NTCCGCGG	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.47	GGANGC	NA	NA	0.63	TGGANGNG	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
mmu-miR-546	0.814815	0.00000206

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-760-5p	0.482759	0.0000124

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