TargetScan_40 megaCluster: 7 Residual: 0.19

Summary

Title Cluster Residual Bicluster Conditions Residual Permutation P-Value Var. Exp. First PC Var. Exp. First PC Perm. P-Value
TargetScan_40 7 0.19 15 0 0.936717 0

Members

Displaying 1 - 50 of 50
101240 WD repeat domain 91

Details for - - WD repeat domain 91

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 101240

Tuberculist Genomic Region

11632 aryl-hydrocarbon receptor-interacting protein

Details for - - aryl-hydrocarbon receptor-interacting protein

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 11632

Tuberculist Genomic Region

15356 3-hydroxy-3-methylglutaryl-Coenzyme A lyase

Details for RP23-161N17.7 - 3-hydroxy-3-methylglutaryl-Coenzyme A lyase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 15356

Tuberculist Genomic Region

19364 RAD51 homolog D

Details for RP23-169P3.1 - RAD51 homolog D

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 19364

Tuberculist Genomic Region

22057 transducer of ErbB-2.1

Details for RP23-244C22.1 - transducer of ErbB-2.1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 22057

Tuberculist Genomic Region

22225 ubiquitin specific peptidase 5 (isopeptidase T)

Details for - - ubiquitin specific peptidase 5 (isopeptidase T)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 22225

Tuberculist Genomic Region

22273 ubiquinol-cytochrome c reductase core protein 1

Details for - - ubiquinol-cytochrome c reductase core protein 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 22273

Tuberculist Genomic Region

22719 zinc finger protein 61

Details for - - zinc finger protein 61

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 22719

Tuberculist Genomic Region

228913 zinc finger protein 217

Details for RP23-233M15.1 - zinc finger protein 217

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 228913

Tuberculist Genomic Region

234814 methenyltetrahydrofolate synthetase domain containing

Details for - - methenyltetrahydrofolate synthetase domain containing

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 234814

Tuberculist Genomic Region

236193 zinc finger protein 709

Details for - - zinc finger protein 709

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 236193

Tuberculist Genomic Region

238024 fructosamine 3 kinase related protein

Details for RP23-293H17.3 - fructosamine 3 kinase related protein

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 238024

Tuberculist Genomic Region

269639 zinc finger protein 512

Details for - - zinc finger protein 512

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 269639

Tuberculist Genomic Region

28199 DDB1 and CUL4 associated factor 11

Details for - - DDB1 and CUL4 associated factor 11

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 28199

Tuberculist Genomic Region

319322 splicing factor 3b, subunit 2

Details for - - splicing factor 3b, subunit 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 319322

Tuberculist Genomic Region

54484 makorin, ring finger protein, 1

Details for - - makorin, ring finger protein, 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 54484

Tuberculist Genomic Region

57279 solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20

Details for - - solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 57279

Tuberculist Genomic Region

57895 coiled-coil domain containing 126

Details for - - coiled-coil domain containing 126

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 57895

Tuberculist Genomic Region

58248 RIKEN cDNA 1700123O20 gene

Details for MNCb-2990 - RIKEN cDNA 1700123O20 gene

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 58248

Tuberculist Genomic Region

60365 RNA binding motif protein 8a

Details for - - RNA binding motif protein 8a

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 60365

Tuberculist Genomic Region

66653 BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like

Details for - - BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 66653

Tuberculist Genomic Region

67487 DEAH (Asp-Glu-Ala-His) box polypeptide 40

Details for RP23-366M19.4 - DEAH (Asp-Glu-Ala-His) box polypeptide 40

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 67487

Tuberculist Genomic Region

69871 protein phosphatase 1, regulatory subunit 35

Details for - - protein phosphatase 1, regulatory subunit 35

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 69871

Tuberculist Genomic Region

70233 CD2 antigen (cytoplasmic tail) binding protein 2

Details for - - CD2 antigen (cytoplasmic tail) binding protein 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 70233

Tuberculist Genomic Region

72144 solute carrier family 37 (glycerol-3-phosphate transporter), member 3

Details for - - solute carrier family 37 (glycerol-3-phosphate transporter), member 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 72144

Tuberculist Genomic Region

72284 oral cancer overexpressed 1

Details for - - oral cancer overexpressed 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 72284

Tuberculist Genomic Region

78246 PHD finger protein 23

Details for RP23-172M21.13-002 - PHD finger protein 23

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 78246

Tuberculist Genomic Region

100972 RAB28, member RAS oncogene family

Details for - - RAB28, member RAS oncogene family

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 100972

Tuberculist Genomic Region

104112 ATP citrate lyase

Details for RP23-392I3.9 - ATP citrate lyase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 104112

Tuberculist Genomic Region

104479 coiled-coil domain containing 117

Details for RP23-288K19.5 - coiled-coil domain containing 117

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 104479

Tuberculist Genomic Region

11409 acyl-Coenzyme A dehydrogenase, short chain

Details for - - acyl-Coenzyme A dehydrogenase, short chain

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 11409

Tuberculist Genomic Region

15468 protein arginine N-methyltransferase 2

Details for - - protein arginine N-methyltransferase 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 15468

Tuberculist Genomic Region

17939 N-acetyl galactosaminidase, alpha

Details for - - N-acetyl galactosaminidase, alpha

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17939

Tuberculist Genomic Region

18415 heat shock protein 4 like

Details for - - heat shock protein 4 like

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 18415

Tuberculist Genomic Region

217827 nrde-2 necessary for RNA interference, domain containing

Details for - - nrde-2 necessary for RNA interference, domain containing

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 217827

Tuberculist Genomic Region

226646 NADH dehydrogenase (ubiquinone) Fe-S protein 2

Details for - - NADH dehydrogenase (ubiquinone) Fe-S protein 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 226646

Tuberculist Genomic Region

227620 UDP-N-acteylglucosamine pyrophosphorylase 1-like 1

Details for RP23-47P18.3 - UDP-N-acteylglucosamine pyrophosphorylase 1-like 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 227620

Tuberculist Genomic Region

26889 ceroid-lipofuscinosis, neuronal 8

Details for - - ceroid-lipofuscinosis, neuronal 8

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 26889

Tuberculist Genomic Region

27267 cysteinyl-tRNA synthetase

Details for - - cysteinyl-tRNA synthetase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 27267

Tuberculist Genomic Region

382010 centrosomal protein 44

Details for - - centrosomal protein 44

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 382010

Tuberculist Genomic Region

56357 isovaleryl coenzyme A dehydrogenase

Details for RP23-172B16.1 - isovaleryl coenzyme A dehydrogenase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 56357

Tuberculist Genomic Region

56401 leprecan 1

Details for RP23-344D2.11-004 - leprecan 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 56401

Tuberculist Genomic Region

66822 F-box protein 25

Details for - - F-box protein 25

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 66822

Tuberculist Genomic Region

68877 MAF1 homolog (S. cerevisiae)

Details for - - MAF1 homolog (S. cerevisiae)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 68877

Tuberculist Genomic Region

69596 adaptor-related protein 5 complex, sigma 1 subunit

Details for RP23-387C21.2 - adaptor-related protein 5 complex, sigma 1 subunit

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 69596

Tuberculist Genomic Region

69962 methyltransferase like 18

Details for - - methyltransferase like 18

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 69962

Tuberculist Genomic Region

70207 translational activator of mitochondrially encoded cytochrome c oxidase I

Details for RP23-81G14.4 - translational activator of mitochondrially encoded cytochrome c oxidase I

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 70207

Tuberculist Genomic Region

73658 spinster homolog 1

Details for - - spinster homolog 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 73658

Tuberculist Genomic Region

73739 chibby homolog 1 (Drosophila)

Details for - - chibby homolog 1 (Drosophila)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 73739

Tuberculist Genomic Region

80743 vacuolar protein sorting 16 (yeast)

Details for RP23-29K12.8 - vacuolar protein sorting 16 (yeast)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 80743

Tuberculist Genomic Region

TFBS DB TF

TFs percTargets pValue
FOXB1_forkhead_full_monomeric_9_1 0.14 0.00000484

GO Terms

Displaying 1 - 1 of 1
GO Terms
NA

Upstream MEME Motif

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif2 E-Value Motif2 Consensus Motif2 Matches
0.0000000012 AAAARAARAMA NA 320000 GCGCATGCGCA V$ZFP206_01_M01742, V$NRF1_Q6_M00652, NRF1_NRF_full_dimeric_12_1

Upstream Weeder Motif

Motif1 Score Motif1 Consensus Motif1 Matches Motif2 Score Motif2 Consensus Motif2 Matches
1.07 GTCCCG V$SP2_01_M01783 1.14 GACGCGGT NA

3p UTR Weeder

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif1 Model Motif2 E-Value Motif2 Consensus Motif2 Matches Motif2 Model
0.48 CGGCGC NA NA 0.65 GGCNTGGC NA NA

3p UTR PITA

miRNAs percTargets pValue
NA

3p UTR TargetScan

miRNAs percTargets pValue
NA

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