Module 212 Residual: 0.55

Title Bicluster Model Residual Score
bicluster_0212 v02 0.55 -15.32
Displaying 1 - 18 of 18
Rv0879c POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN

Details for Rv0879c - POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.63 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0879c

Tuberculist Genomic Region

Rv1079 Cystathionine gamma-lyase (EC 4.4.1.1)

Details for Rv1079 - Cystathionine gamma-lyase (EC 4.4.1.1)

GO Terms: GO:0004123, GO:0003962, GO:0004123, GO:0005886, GO:0019279, GO:0019343

PATRIC Pathways: Selenoamino acid metabolism, Cysteine and methionine metabolism, Glycine, serine and threonine metabolism, Nitrogen metabolism

Essentiality: Griffin Essential: 0.26 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1079

Tuberculist Genomic Region

Rv2201 Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4)

Details for Rv2201 - Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4)

GO Terms: GO:0004066, GO:0005576, GO:0005829, GO:0005886, GO:0040007

PATRIC Pathways: Nitrogen metabolism, Alanine, aspartate and glutamate metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.05 | In vivo Essential: NA

Go to Gene Page: Rv2201

Tuberculist Genomic Region

Rv2229c

Details for Rv2229c -

GO Terms: GO:0005618, GO:0005886, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.08 | In vitro Essential: 0.07 | In vivo Essential: NA

Go to Gene Page: Rv2229c

Tuberculist Genomic Region

Rv2563 Glutamine-transport transmembrane protein ABC transporter

Details for Rv2563 - Glutamine-transport transmembrane protein ABC transporter

GO Terms: GO:0005576, GO:0005886, GO:0005887

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.27 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2563

Tuberculist Genomic Region

Rv2567 Protein containing domains DUF404, DUF407, DUF403

Details for Rv2567 - Protein containing domains DUF404, DUF407, DUF403

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.02 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2567

Tuberculist Genomic Region

Rv2992c Glutamyl-tRNA synthetase (EC 6.1.1.17) @ Glutamyl-tRNA(Gln) synthetase (EC 6.1.1.24)

Details for Rv2992c - Glutamyl-tRNA synthetase (EC 6.1.1.17) @ Glutamyl-tRNA(Gln) synthetase (EC 6.1.1.24)

GO Terms: GO:0005886, GO:0040007

PATRIC Pathways: Aminoacyl-tRNA biosynthesis, Porphyrin and chlorophyll metabolism, Aminoacyl-tRNA biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.05 | In vivo Essential: NA

Go to Gene Page: Rv2992c

Tuberculist Genomic Region

Rv2993c 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) / 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68)

Details for Rv2993c - 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) / 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68)

GO Terms: NA

PATRIC Pathways: Tyrosine metabolism, alpha-Linolenic acid metabolism, Tyrosine metabolism

Essentiality: Griffin Essential: 0.43 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2993c

Tuberculist Genomic Region

Rv3233c Wax ester synthase/acyl-CoA:diacylglycerol acyltransferase

Details for Rv3233c - Wax ester synthase/acyl-CoA:diacylglycerol acyltransferase

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 1.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3233c

Tuberculist Genomic Region

Rv3234c Wax ester synthase/acyl-CoA:diacylglycerol acyltransferase

Details for Rv3234c - Wax ester synthase/acyl-CoA:diacylglycerol acyltransferase

GO Terms: GO:0001666, GO:0004144, GO:0045017

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.90 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3234c

Tuberculist Genomic Region

Rv3575c Transcriptional regulator, LacI family

Details for Rv3575c - Transcriptional regulator, LacI family

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.99 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3575c

Tuberculist Genomic Region

Rv3598c Lysyl-tRNA synthetase (class II) (EC 6.1.1.6)

Details for Rv3598c - Lysyl-tRNA synthetase (class II) (EC 6.1.1.6)

GO Terms: GO:0004824, GO:0040007

PATRIC Pathways: Aminoacyl-tRNA biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.02 | In vivo Essential: NA

Go to Gene Page: Rv3598c

Tuberculist Genomic Region

Rv2199c Probable cytochrome c oxidase polypeptide 4 (EC 1.9.3.1)

Details for Rv2199c - Probable cytochrome c oxidase polypeptide 4 (EC 1.9.3.1)

GO Terms: NA

PATRIC Pathways: Oxidative phosphorylation

Essentiality: Griffin Essential: 0.06 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2199c

Tuberculist Genomic Region

Rv2200c Cytochrome c oxidase polypeptide II (EC 1.9.3.1)

Details for Rv2200c - Cytochrome c oxidase polypeptide II (EC 1.9.3.1)

GO Terms: GO:0004129, GO:0005576, GO:0005886, GO:0005887, GO:0040007

PATRIC Pathways: Oxidative phosphorylation

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.05 | In vivo Essential: NA

Go to Gene Page: Rv2200c

Tuberculist Genomic Region

Rv2230c

Details for Rv2230c -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.22 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2230c

Tuberculist Genomic Region

Rv2231c L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)

Details for Rv2231c - L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)

GO Terms: GO:0048472, GO:0040007

PATRIC Pathways: Porphyrin and chlorophyll metabolism

Essentiality: Griffin Essential: 0.22 | In vitro Essential: 0.12 | In vivo Essential: 0.34

Go to Gene Page: Rv2231c

Tuberculist Genomic Region

Rv2994 Integral membrane transport protein

Details for Rv2994 - Integral membrane transport protein

GO Terms: GO:0005576

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.72 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2994

Tuberculist Genomic Region

Rv3576 Serine/threonine protein kinase (EC 2.7.11.1)

Details for Rv3576 - Serine/threonine protein kinase (EC 2.7.11.1)

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.59 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3576

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 0.0000025 e-value: 0.00031
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
No enrichment
Displaying 1 - 18 of 18
GO:0004123 |

cystathionine gamma-lyase activity

GO:0003962 |

cystathionine gamma-synthase activity

GO:0005886 |

plasma membrane

GO:0019279 |

L-methionine biosynthetic process from L-homoserine via cystathionine

GO:0019343 |

cysteine biosynthetic process via cystathionine

GO:0004066 |

asparagine synthase (glutamine-hydrolyzing) activity

GO:0005576 |

extracellular region

GO:0005829 |

cytosol

GO:0040007 |

growth

GO:0005618 |

cell wall

GO:0005887 |

integral to plasma membrane

GO:0001666 |

response to hypoxia

GO:0004144 |

diacylglycerol O-acyltransferase activity

GO:0045017 |

glycerolipid biosynthetic process

GO:0004824 |

lysine-tRNA ligase activity

GO:0004129 |

cytochrome-c oxidase activity

GO:0048472 |

threonine-phosphate decarboxylase activity