Module 388 Residual: 0.53

Title Bicluster Model Residual Score
bicluster_0388 v02 0.53 -17.30
Displaying 1 - 18 of 18
Rv0937c Ku domain protein

Details for Rv0937c - Ku domain protein

GO Terms: GO:0003690, GO:0005515, GO:0006303, GO:0033202, GO:0042803

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.32 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0937c

Tuberculist Genomic Region

Rv0938 ATP-dependent DNA ligase (EC 6.5.1.1) clustered with Ku protein, LigD

Details for Rv0938 - ATP-dependent DNA ligase (EC 6.5.1.1) clustered with Ku protein, LigD

GO Terms: GO:0000287, GO:0003887, GO:0003896, GO:0003899, GO:0003909, GO:0003910, GO:0004652, GO:0005515, GO:0005524, GO:0005886, GO:0006269, GO:0006303, GO:0008310, GO:0030145

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0938

Tuberculist Genomic Region

Rv0939 Fumarylacetoacetase (EC 3.7.1.2)

Details for Rv0939 - Fumarylacetoacetase (EC 3.7.1.2)

GO Terms: GO:0004334, GO:0005829, GO:0005886

PATRIC Pathways: alpha-Linolenic acid metabolism, Tyrosine metabolism

Essentiality: Griffin Essential: 0.64 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0939

Tuberculist Genomic Region

Rv1011 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (EC 2.7.1.148)

Details for Rv1011 - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (EC 2.7.1.148)

GO Terms: GO:0050515, GO:0040007

PATRIC Pathways: Terpenoid backbone biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.11 | In vivo Essential: NA

Go to Gene Page: Rv1011

Tuberculist Genomic Region

Rv1166 LpqW

Details for Rv1166 - LpqW

GO Terms: GO:0005576, GO:0009247, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.10 | In vivo Essential: NA

Go to Gene Page: Rv1166

Tuberculist Genomic Region

Rv1280c \Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1)\\\""

Details for Rv1280c - \Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1)\\\""

GO Terms: GO:0005215, GO:0006810, GO:0005886, GO:0005887

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.96 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1280c

Tuberculist Genomic Region

Rv1562c Malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141)

Details for Rv1562c - Malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141)

GO Terms: GO:0033942

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.07 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1562c

Tuberculist Genomic Region

Rv1563c Malto-oligosyltrehalose synthase (EC 5.4.99.15)

Details for Rv1563c - Malto-oligosyltrehalose synthase (EC 5.4.99.15)

GO Terms: GO:0047470, GO:0047470

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.07 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1563c

Tuberculist Genomic Region

Rv1564c Glycogen debranching enzyme (EC 3.2.1.-)

Details for Rv1564c - Glycogen debranching enzyme (EC 3.2.1.-)

GO Terms: GO:0005975, GO:0043169, GO:0003824

PATRIC Pathways: Ascorbate and aldarate metabolism, Glycosaminoglycan degradation, Amino sugar and nucleotide sugar metabolism, Ubiquinone and other terpenoid-quinone biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1564c

Tuberculist Genomic Region

Rv2364c GTP-binding protein Era

Details for Rv2364c - GTP-binding protein Era

GO Terms: GO:0003676, GO:0005622, GO:0005525, GO:0005829, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.07 | In vivo Essential: NA

Go to Gene Page: Rv2364c

Tuberculist Genomic Region

Rv0051 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-)

Details for Rv0051 - Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-)

GO Terms: NA

PATRIC Pathways: Peptidoglycan biosynthesis

Essentiality: Griffin Essential: 0.99 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0051

Tuberculist Genomic Region

Rv1281c Oligopeptide transport system permease protein OppD (TC 3.A.1.5.1)

Details for Rv1281c - Oligopeptide transport system permease protein OppD (TC 3.A.1.5.1)

GO Terms: GO:0005215, GO:0016020, GO:0006810, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.97 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1281c

Tuberculist Genomic Region

Rv1282c Oligopeptide transport system permease protein OppC (TC 3.A.1.5.1)

Details for Rv1282c - Oligopeptide transport system permease protein OppC (TC 3.A.1.5.1)

GO Terms: GO:0006810, GO:0016020, GO:0005215

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.22 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1282c

Tuberculist Genomic Region

Rv1283c Oligopeptide transport system permease protein OppB (TC 3.A.1.5.1)

Details for Rv1283c - Oligopeptide transport system permease protein OppB (TC 3.A.1.5.1)

GO Terms: GO:0006810, GO:0005215, GO:0016020

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.28 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1283c

Tuberculist Genomic Region

Rv1522c Putative membrane protein MmpL12

Details for Rv1522c - Putative membrane protein MmpL12

GO Terms: GO:0005829, GO:0052572

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1522c

Tuberculist Genomic Region

Rv1565c O-antigen acetylase

Details for Rv1565c - O-antigen acetylase

GO Terms: GO:0005829, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1565c

Tuberculist Genomic Region

Rv1680 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1)

Details for Rv1680 - Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1)

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.61 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1680

Tuberculist Genomic Region

Rv1681 Molybdopterin biosynthesis protein MoeX

Details for Rv1681 - Molybdopterin biosynthesis protein MoeX

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.98 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1681

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 0.000000055 e-value: 0.047
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
No enrichment
Displaying 1 - 37 of 37
GO:0003690 |

double-stranded DNA binding

GO:0005515 |

protein binding

GO:0006303 |

double-strand break repair via nonhomologous end joining

GO:0033202 |

DNA helicase complex

GO:0042803 |

protein homodimerization activity

GO:0000287 |

magnesium ion binding

GO:0003887 |

DNA-directed DNA polymerase activity

GO:0003896 |

DNA primase activity

GO:0003899 |

DNA-directed RNA polymerase activity

GO:0003909 |

DNA ligase activity

GO:0003910 |

DNA ligase (ATP) activity

GO:0004652 |

polynucleotide adenylyltransferase activity

GO:0005524 |

ATP binding

GO:0005886 |

plasma membrane

GO:0006269 |

DNA replication, synthesis of RNA primer

GO:0008310 |

single-stranded DNA specific 3'-5' exodeoxyribonuclease activity

GO:0030145 |

manganese ion binding

GO:0004334 |

fumarylacetoacetase activity

GO:0005829 |

cytosol

GO:0050515 |

4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity

GO:0040007 |

growth

GO:0005576 |

extracellular region

GO:0009247 |

glycolipid biosynthetic process

GO:0005215 |

transporter activity

GO:0006810 |

transport

GO:0005887 |

integral to plasma membrane

GO:0033942 |

4-alpha-D-{(1->4)-alpha-D-glucano}trehalose trehalohydrolase activity

GO:0047470 |

(1,4)-alpha-D-glucan 1-alpha-D-glucosylmutase activity

GO:0005975 |

carbohydrate metabolic process

GO:0043169 |

cation binding

GO:0003824 |

catalytic activity

GO:0003676 |

nucleic acid binding

GO:0005622 |

intracellular

GO:0005525 |

GTP binding

GO:0016020 |

membrane

GO:0052572 |

response to host immune response