Module 525 Residual: 0.52

Title Bicluster Model Residual Score
bicluster_0525 v02 0.52 -18.40
Displaying 1 - 15 of 15
Rv1519

Details for Rv1519 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.53 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1519

Tuberculist Genomic Region

Rv1773c Transcriptional regulator, IclR family

Details for Rv1773c - Transcriptional regulator, IclR family

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.16 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1773c

Tuberculist Genomic Region

Rv1774 oxidoreductase, FAD-binding

Details for Rv1774 - oxidoreductase, FAD-binding

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 1.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1774

Tuberculist Genomic Region

Rv1775

Details for Rv1775 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.97 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1775

Tuberculist Genomic Region

Rv2121c ATP phosphoribosyltransferase (EC 2.4.2.17)

Details for Rv2121c - ATP phosphoribosyltransferase (EC 2.4.2.17)

GO Terms: GO:0003879, GO:0000287, GO:0003879, GO:0005524, GO:0005886, GO:0016208, GO:0040007, GO:0042803, GO:0051260

PATRIC Pathways: Histidine metabolism

Essentiality: Griffin Essential: 0.01 | In vitro Essential: 0.07 | In vivo Essential: NA

Go to Gene Page: Rv2121c

Tuberculist Genomic Region

Rv2122c Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)

Details for Rv2122c - Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)

GO Terms: GO:0004636, GO:0040007, GO:0042803, GO:0075139

PATRIC Pathways: Histidine metabolism

Essentiality: Griffin Essential: 0.17 | In vitro Essential: 0.05 | In vivo Essential: NA

Go to Gene Page: Rv2122c

Tuberculist Genomic Region

Rv2123 PPE family protein

Details for Rv2123 - PPE family protein

GO Terms: GO:0052572, GO:0075139

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.30 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2123

Tuberculist Genomic Region

Rv2378c L-lysine 6-monooxygenase MbtG (EC 1.14.13.59)

Details for Rv2378c - L-lysine 6-monooxygenase MbtG (EC 1.14.13.59)

GO Terms: GO:0040007

PATRIC Pathways: Lysine degradation

Essentiality: Griffin Essential: 0.68 | In vitro Essential: 0.19 | In vivo Essential: NA

Go to Gene Page: Rv2378c

Tuberculist Genomic Region

Rv2379c Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)

Details for Rv2379c - Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)

GO Terms: GO:0005618, GO:0005829, GO:0005886

PATRIC Pathways: Fatty acid metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2379c

Tuberculist Genomic Region

Rv2380c Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)

Details for Rv2380c - Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)

GO Terms: GO:0000036, GO:0005829, GO:0005886, GO:0031177

PATRIC Pathways: Fatty acid metabolism

Essentiality: Griffin Essential: 0.01 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2380c

Tuberculist Genomic Region

Rv2381c Polyketide synthetase MbtD

Details for Rv2381c - Polyketide synthetase MbtD

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2381c

Tuberculist Genomic Region

Rv2382c Malonyl CoA-acyl carrier protein transacylase (EC 2.3.1.39)

Details for Rv2382c - Malonyl CoA-acyl carrier protein transacylase (EC 2.3.1.39)

GO Terms: GO:0004314, GO:0040007

PATRIC Pathways: Fatty acid biosynthesis

Essentiality: Griffin Essential: 0.42 | In vitro Essential: 0.08 | In vivo Essential: NA

Go to Gene Page: Rv2382c

Tuberculist Genomic Region

Rv2383c Phenyloxazoline synthase MbtB (EC 6.3.2.-)

Details for Rv2383c - Phenyloxazoline synthase MbtB (EC 6.3.2.-)

GO Terms: GO:0000036, GO:0005886, GO:0009405, GO:0010106, GO:0019290, GO:0031177, GO:0052572

PATRIC Pathways: Tryptophan metabolism, Biosynthesis of siderophore group nonribosomal peptides

Essentiality: Griffin Essential: 0.96 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2383c

Tuberculist Genomic Region

Rv2386c isochorismate synthase MbtI

Details for Rv2386c - isochorismate synthase MbtI

GO Terms: GO:0004049, GO:0000287, GO:0004106, GO:0005886, GO:0008909, GO:0009697, GO:0010106, GO:0019290, GO:0040007, GO:0043904, GO:0052572

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.15 | In vivo Essential: NA

Go to Gene Page: Rv2386c

Tuberculist Genomic Region

Rv3402c DegT/DnrJ/EryC1 family protein

Details for Rv3402c - DegT/DnrJ/EryC1 family protein

GO Terms: GO:0005576, GO:0010106, GO:0052572

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.97 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3402c

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 0.000000000055 e-value: 5.2
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
No enrichment
Displaying 1 - 26 of 26
GO:0003879 |

ATP phosphoribosyltransferase activity

GO:0000287 |

magnesium ion binding

GO:0005524 |

ATP binding

GO:0005886 |

plasma membrane

GO:0016208 |

AMP binding

GO:0040007 |

growth

GO:0042803 |

protein homodimerization activity

GO:0051260 |

protein homooligomerization

GO:0004636 |

phosphoribosyl-ATP diphosphatase activity

GO:0075139 |

response to host iron concentration

GO:0052572 |

response to host immune response

GO:0005618 |

cell wall

GO:0005829 |

cytosol

GO:0000036 |

ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process

GO:0031177 |

phosphopantetheine binding

GO:0004314 |

[acyl-carrier-protein] S-malonyltransferase activity

GO:0009405 |

pathogenesis

GO:0010106 |

cellular response to iron ion starvation

GO:0019290 |

siderophore biosynthetic process

GO:0004049 |

anthranilate synthase activity

GO:0004106 |

chorismate mutase activity

GO:0008909 |

isochorismate synthase activity

GO:0009697 |

salicylic acid biosynthetic process

GO:0043904 |

isochorismate pyruvate lyase activity

GO:0005576 |

extracellular region