Rv1033c DNA-binding response regulator TrcR

Rv1033c (DNA-binding response regulator TrcR) is predicted to be co-regulated in modules bicluster_0028 with residual 0.52 and bicluster_0299 with residual 0.50.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.00 and 1.50 for bicluster_0028 and 0.00 and 48.00 for bicluster_0299 respectively.

These modules are enriched for following go terms: signal transduction, signaling, single organism signaling, cell communication, response to stimulus, signal transducer activity, molecular transducer activity, phosphorelay sensor kinase activity, receptor activity, signaling receptor activity .

This gene is found to be for growth on cholesterol.

Mutant available?: Yes

Displaying 21 - 30 of 246
Gene Target Differential Expression Distance Expression pvalue Type
Ribonucleotide-diphosphate reductase subunit beta (EC 1.17.4.1)
No 7 0.02 0.989357 CDS
No 12 0.03 0.98198 Primary.TSS
No -16 -0.02 0.988415 Primary.TSS
3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100)
No -3 0.19 0.823199 Primary.TSS
3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9)
No -23 0 0.99668 Primary.TSS
Heat shock protein hsp
No 42 -0.28 0.759515 CDS
Predicted cobalt transporter in Mycobacteria
No 66 -0.12 0.891713 Primary.TSS
No -12 -0.19 0.824509 Primary.TSS
ATP-dependent DNA ligase (EC 6.5.1.1)
Repressed 13 -1.13 0.00000000000726 Internal.TSS
ATP-dependent DNA ligase (EC 6.5.1.1)
Repressed 4 -1.13 0.00000000000726 CDS
not assigned to any KEGG Pathway.
GO:0008150

biological_process

biological_process

Details: 
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO Category: 
biological_process
66
Total items in this category:  
GO:0008150

biological_process

biological_process

Details: 
Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO Category: 
biological_process
66
Total items in this category:  
GO:0003677

DNA binding

DNA binding

Details: 
Any molecular function by which a gene product interacts selectively with DNA (deoxyribonucleic acid).
GO Category: 
molecular_function
37
Total items in this category:  
GO:0045892

negative regulation of transcription, DNA-dependent

negative regulation of transcription, DNA-dependent

Details: 
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-dependent transcription.
GO Category: 
biological_process
10
Total items in this category:  
GO:0045893

positive regulation of transcription, DNA-dependent

positive regulation of transcription, DNA-dependent

Details: 
Any process that activates or increases the frequency, rate or extent of cellular DNA-dependent transcription.
GO Category: 
biological_process
14
Total items in this category:  
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 11.55 U
D3I 3 3 3.83 11.61 I
D3U 3 3 3.83 11.08 U
D5I 9 5 6.00 10.97 I
D5U 17 5 6.00 11.46 U
D7I 18 7 8.14 10.63 I
D7U 19 7 8.14 11.98 U
D14I 4 14 15.63 6.31 I
D14U 4 14 15.63 10.65 U
D17I 3 17 19.15 2.70 I
D17U 3 17 19.15 9.95 U
D21I 4 21 23.23 7.95 I
D21U 4 21 23.23 9.70 U
D24I 3 24 26.60 I
D24U 3 24 26.60 9.04 U
D28I 4 28 30.61 4.20 I
D28U 4 28 30.61 9.07 U