Rv2250c Transcriptional regulator, TetR family

Rv2250c (Transcriptional regulator, TetR family) is predicted to be co-regulated in modules bicluster_0107 with residual 0.57 and bicluster_0461 with residual 0.55.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 3.30 and 320.00 for bicluster_0107 and 23.00 and 620.00 for bicluster_0461 respectively.

These modules are enriched for following go terms: .

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 131 - 140 of 152
Gene Target Differential Expression Distance Expression pvalue Type
probable DNA methylase
No -77 -0.3 0.427819 CDS
Cell envelope-associated transcriptional attenuator LytR-CpsA-Psr, subfamily A1 (as in PMID19099556)
Repressed -8 -1.55 1.85e-20 Primary.TSS
D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4)
Repressed -84 -1.23 0.000000026 Primary.TSS
4-hydroxy-3-methylbut-2-enyl diphosphate reductase (EC 1.17.1.2)
No 15 -0.87 0.133651 Primary.TSS
Octaprenyl-diphosphate synthase (EC 2.5.1.-) / Dimethylallyltransferase (EC 2.5.1.1) / Geranyltranstransferase (farnesyldiphosphate synthase) (EC 2.5.1.10) / Geranylgeranyl pyrophosphate synthetase (EC 2.5.1.29)
No 15 -0.85 0.202568 Internal.TSS
Cholesterol oxidase (EC 1.1.3.6)
No -40 0.35 0.514614 Primary.TSS
SSU ribosomal protein S4p (S9e)
No -64 -0.05 0.877635 CDS
Terminal oxygenase KshA
No 10 -0.49 0.161161 Primary.TSS
Arsenic efflux pump protein
No -2 -0.1 0.789027 CDS
Lipoprotein LpqE
No -142 0.12 0.708368 Primary.TSS
not assigned to any KEGG Pathway.
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 10.01 U
D3I 3 3 3.83 9.38 I
D3U 3 3 3.83 9.58 U
D5I 9 5 6.00 11.08 I
D5U 17 5 6.00 12.64 U
D7I 18 7 8.14 7.09 I
D7U 19 7 8.14 9.43 U
D14I 4 14 15.63 4.67 I
D14U 4 14 15.63 6.80 U
D17I 3 17 19.15 I
D17U 3 17 19.15 5.89 U
D21I 4 21 23.23 2.16 I
D21U 4 21 23.23 5.60 U
D24I 3 24 26.60 I
D24U 3 24 26.60 5.14 U
D28I 4 28 30.61 I
D28U 4 28 30.61 5.35 U