Rv2250c Transcriptional regulator, TetR family

Rv2250c (Transcriptional regulator, TetR family) is predicted to be co-regulated in modules bicluster_0107 with residual 0.57 and bicluster_0461 with residual 0.55.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 3.30 and 320.00 for bicluster_0107 and 23.00 and 620.00 for bicluster_0461 respectively.

These modules are enriched for following go terms: .

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 141 - 150 of 152
Gene Target Differential Expression Distance Expression pvalue Type
Septum site-determining protein MinD @ possible CpaE
No 30 -0.84 0.290962 Primary.TSS
Phosphoserine phosphatase (EC 3.1.3.3)
No -137 0.15 0.426339 Primary.TSS
Arsenical pump-driving ATPase (EC 3.6.3.16)
No 69 -0.04 0.884632 Antisense.TSS
2-isopropylmalate synthase (EC 2.3.3.13)
Repressed -8 -1.63 2.98e-30 Primary.TSS
DNA polymerase III epsilon subunit (EC 2.7.7.7)
Repressed 31 -1.5 1.19e-18 Primary.TSS
alkyl sulfatase (EC 3.1.6.-)
Induced 7 0.85 0.0104809 Antisense.TSS
Antigen 85-C precursor (85C) (Antigen 85 complex C) (Ag85C) (Mycolyl transferase 85C) (EC 2.3.1.-)
No -130 0.03 0.966053 Primary.TSS
POSSIBLE MEMBRANE PROTEIN
No 27 -0.02 0.977425 CDS
monooxygenase, flavin-binding family
Repressed 17 -1.27 0.000491609 Primary.TSS
Transcriptional repressor EthR, TetR family
No -15 -0.51 0.28834 Primary.TSS
not assigned to any KEGG Pathway.
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 10.01 U
D3I 3 3 3.83 9.38 I
D3U 3 3 3.83 9.58 U
D5I 9 5 6.00 11.08 I
D5U 17 5 6.00 12.64 U
D7I 18 7 8.14 7.09 I
D7U 19 7 8.14 9.43 U
D14I 4 14 15.63 4.67 I
D14U 4 14 15.63 6.80 U
D17I 3 17 19.15 I
D17U 3 17 19.15 5.89 U
D21I 4 21 23.23 2.16 I
D21U 4 21 23.23 5.60 U
D24I 3 24 26.60 I
D24U 3 24 26.60 5.14 U
D28I 4 28 30.61 I
D28U 4 28 30.61 5.35 U