Rv3681c WhiB-type transcription regulator

Rv3681c (WhiB-type transcription regulator) is predicted to be co-regulated in modules bicluster_0400 with residual 0.51 and bicluster_0421 with residual 0.58.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.01 and 0.12 for bicluster_0400 and 360.00 and 130.00 for bicluster_0421 respectively.

These modules are enriched for following go terms: carboxypeptidase activity, thiosulfate sulfurtransferase activity, unfolded protein binding, exopeptidase activity .

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 11 - 20 of 56
Gene Target Differential Expression Distance Expression pvalue Type
No -88 -0.09 0.999973 CDS
DNA or RNA helicases of superfamily II
No 61 -0.66 0.170386 Primary.TSS
Polyketide synthase
No -106 -0.63 0.0609922 Primary.TSS
integration host factor
No -39 -0.03 0.999973 Primary.TSS
S-adenosylmethionine synthetase (EC 2.5.1.6)
No -67 0.04 0.999973 Primary.TSS
No -50 0.8 0.851789 CDS
Transcriptional repressor Mce3R, TetR family
No 39 0.05 0.999973 Primary.TSS
5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
No 46 -0.08 0.999973 Primary.TSS
Undecaprenyl-diphosphatase (EC 3.6.1.27)
No 26 0.11 0.999973 Primary.TSS
No -9 -0.04 0.999973 Antisense.TSS
not assigned to any KEGG Pathway.
GO:0005618

cell wall

cell wall

Details: 
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan.
GO Category: 
cellular_component
320
Total items in this category:  
GO:0042803

protein homodimerization activity

protein homodimerization activity

Details: 
Interacting selectively and non-covalently with an identical protein to form a homodimer.
GO Category: 
molecular_function
83
Total items in this category:  
GO:0047134

protein-disulfide reductase activity

protein-disulfide reductase activity

Details: 
Catalysis of the reaction: protein-dithiol + NAD(P)+ = protein-disulfide + NAD(P)H + H+.
GO Category: 
molecular_function
2
Total items in this category:  
GO:0051539

4 iron, 4 sulfur cluster binding

4 iron, 4 sulfur cluster binding

Details: 
Interacting selectively and non-covalently with a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
GO Category: 
molecular_function
5
Total items in this category:  
No TFOE experiment results were found

TRIP log2 fold abundance change

NA