MMP0417 MMP0417 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)me thylideneamino)imidazole-4-carboxamide isomerase (NCBI)

Methanococcus maripaludis S2

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Summary

	Locus Tag	Symbol	Synonyms	Product	Protein Synonyms	Start	End	Strand	PubMed ID
MMP0417	MMP0417	hisA	hisA, MMP0417	1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)me thylideneamino)imidazole-4-carboxamide isomerase...	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase (EC 5.3.1.16) (Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase)	418670	419395	+	15466049

Regulatory Modules

	Residual	Motif 1	Expression Plot
mmp-bicluster_0060	0.24
mmp-bicluster_0137	0.25

XReference

Uniprot	NCBI Gene	NCBI Protein	GI Number	MicrobesOnline	EnsemblBacteria	InterPro	EggNOG
P62357	2762631	NP_987537.1;	45357980	532609	CAF29973	IPR013785, IPR006062, IPR006063, IPR023016, IPR011060	COG0106

Mutations

Line	Position	Effect	Impact	Class	Percent Frequency	Sample	Title

Transposon mutants

Title	Insert	TAG Module
MMP0417

Homology

Orthologues	Paralogues

Functions

Catalytic Activity	COG	EC Description	Protein families	TIGR Roles
1-(5-phospho-beta-D-ribosyl)-5-((5-phospho-beta-D-ribosylamino)methylideneamino)imidazole-4-carboxamide = 5-((5-phospho-1-deoxy-D-ribulos-1-ylamino)methylideneamino)-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide. {ECO:0000255|HAMAP-Rule:MF_01014}.	(E) COG106 | Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	(5.3.1.16) isomerase.	HisA/HisF family	Amino acid biosynthesis:Histidine family

Essentiality

L1.Cm.T1	L1.Cm.T2	L1.cN.T1	L1.cN.T2	L1.T0	L2.Cm.T1	L2.Cm.T2	L2.cN.T1	L2.cN.T2	L2.T0
2	2	1	0	8	2	2	1	0	4

Product Synonyms

Product (LegacyBRC)	Product (RefSeq)

Operon

Refseq

GI Number	Accession	Blast	Conserved Domains
45357980	NP_987537.1	Run

GO Terms

GO:0000105 GO:0003949 -

GO:0000105

GO:0003949

String Network

Link to STRINGS	STRINGS Network
MMP0417

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