Methanococcus maripaludis S2 Module 60 Residual: 0.24

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Summary

Residual: 0.24 Score: -17.5174 version: mmp_cmonkey_11_Oct_11

Members

MMP0081 glutamate synthase; large subunit; archaeal subunit 2 (NCBI)

Details for MMP0081 - glutamate synthase; large subunit; archaeal subunit 2 (NCBI)

GO Terms: GO:0006537, GO:0006118, GO:0006207, GO:0009342, GO:0004152, GO:0051536, GO:0004355, GO:0009055, GO:0016040

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0081

Tuberculist Genomic Region

MMP1188 conserved hypothetical archaeal protein (NCBI)

Details for MMP1188 - conserved hypothetical archaeal protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1188

Tuberculist Genomic Region

MMP0224 glutamate-1-semialdehyde aminotransferase (NCBI)

Details for MMP0224 - glutamate-1-semialdehyde aminotransferase (NCBI)

GO Terms: GO:0033014, GO:0008483, GO:0030170, GO:0042286

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0224

Tuberculist Genomic Region

MMP1189 Ribose 5-phosphate isomerase (NCBI)

Details for MMP1189 - Ribose 5-phosphate isomerase (NCBI)

GO Terms: GO:0009052, GO:0004751

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1189

Tuberculist Genomic Region

MMP0297 translation initiation factor aIF-2 subunit beta (NCBI)

Details for MMP0297 - translation initiation factor aIF-2 subunit beta (NCBI)

GO Terms: GO:0006413, GO:0003743

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0297

Tuberculist Genomic Region

MMP1255 Phenylalanyl-tRNA synthetase beta subunit (NCBI)

Details for MMP1255 - Phenylalanyl-tRNA synthetase beta subunit (NCBI)

GO Terms: GO:0006432, GO:0009328, GO:0004826, GO:0005524

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1255

Tuberculist Genomic Region

MMP0417 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)me thylideneamino)imidazole-4-carboxamide isomerase (NCBI)

Details for MMP0417 - 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)me thylideneamino)imidazole-4-carboxamide isomerase (NCBI)

GO Terms: GO:0000105, GO:0003949

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0417

Tuberculist Genomic Region

MMP1480 aconitase Family (NCBI)

Details for MMP1480 - aconitase Family (NCBI)

GO Terms: GO:0009098, GO:0051539, GO:0003861

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1480

Tuberculist Genomic Region

MMP0418 Carbohydrate kinase, PfkB (NCBI)

Details for MMP0418 - Carbohydrate kinase, PfkB (NCBI)

GO Terms: GO:0006014, GO:0004747

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0418

Tuberculist Genomic Region

MMP0080 glutamate synthase; large subunit; archaeal subunit 1 (NCBI)

Details for MMP0080 - glutamate synthase; large subunit; archaeal subunit 1 (NCBI)

GO Terms: GO:0009113, GO:0009342, GO:0004044, GO:0004355

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0080

Tuberculist Genomic Region

MMP0894 GMP synthase (glutamine-hydrolyzing). (NCBI)

Details for MMP0894 - GMP synthase (glutamine-hydrolyzing). (NCBI)

GO Terms: GO:0006177, GO:0009435, GO:0008033, GO:0005737, GO:0003922, GO:0005524, GO:0004808, GO:0003952

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0894

Tuberculist Genomic Region

MMP0696 Prolyl-tRNA synthetase (NCBI)

Details for MMP0696 - Prolyl-tRNA synthetase (NCBI)

GO Terms: GO:0006433, GO:0005737, GO:0004827, GO:0005524

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0696

Tuberculist Genomic Region

MMP0955 succinate--CoA ligase (ADP-forming); alpha subunit (NCBI)

Details for MMP0955 - succinate--CoA ligase (ADP-forming); alpha subunit (NCBI)

GO Terms: GO:0008152, GO:0009361, GO:0004775

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0955

Tuberculist Genomic Region

MMP0880 2-oxosuberate synthase, last step (NCBI)

Details for MMP0880 - 2-oxosuberate synthase, last step (NCBI)

GO Terms: GO:0009098, GO:0003862, GO:0051287

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0880

Tuberculist Genomic Region

MMP1017 Aspartate kinase (NCBI)

Details for MMP1017 - Aspartate kinase (NCBI)

GO Terms: GO:0008652, GO:0016597, GO:0004072

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1017

Tuberculist Genomic Region

MMP0893 CTP synthase (NCBI)

Details for MMP0893 - CTP synthase (NCBI)

GO Terms: GO:0006221, GO:0003883

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0893

Tuberculist Genomic Region

MMP1146 Amidophosphoribosyltransferase (NCBI)

Details for MMP1146 - Amidophosphoribosyltransferase (NCBI)

GO Terms: GO:0009113, GO:0009116, GO:0004044

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1146

Tuberculist Genomic Region

MMP1640 Archaeal S-adenosylmethionine synthetase (MAT) (NCBI)

Details for MMP1640 - Archaeal S-adenosylmethionine synthetase (MAT) (NCBI)

GO Terms: GO:0006730, GO:0048269, GO:0048270, GO:0005524, GO:0004478

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1640

Tuberculist Genomic Region

Displaying 1 - 18 of 18

Motifs

Motif 1: e-value: 1800 e-value: 2900

Module Plots

Regulation

Regulator Interaction Influence Weight Other Influences

MMP1303

Sensory transduction histidine kinase (NCBI)

MMP1646

conserved hypothetical archaeal protein (NCBI)
 up-regulates 0.41

MMP1303

MMP1646

MMP0033

LysR family member (NCBI)

H2

 up-regulates 0.29

MMP0033

H2

MMP1015

Transcription factor CBF/NF-Y/archaeal histone:Histone-fold/TFIID-TAF/NF-Y domain (NCBI)
 down-regulates -0.24

MMP1015

MMP0052

Conserved Hypothetical protein with 2 CBS domains (NCBI)
 down-regulates -0.10

MMP0052

GO Enrichment

Category: BP
Category GO ID GO Term Annotated Expected Significant p-value
BP GO:0019693 ribose phosphate metabolic process 27 0.70 3 0.0210
BP GO:0006753 nucleoside phosphate metabolic process 31 0.81 3 0.0310
BP GO:0009117 nucleotide metabolic process 31 0.81 3 0.0310
BP GO:0044710 single-organism metabolic process 99 2.58 5 0.0350
BP GO:0044238 primary metabolic process 101 2.63 5 0.0380
BP GO:1901135 carbohydrate derivative metabolic proces... 34 0.89 3 0.0400
Category: MF
Category GO ID GO Term Annotated Expected Significant p-value
MF GO:0043168 anion binding 196 2.79 6 0.0360
MF GO:0005524 ATP binding 147 2.09 5 0.0400
MF GO:0030554 adenyl nucleotide binding 149 2.12 5 0.0430
MF GO:0032559 adenyl ribonucleotide binding 149 2.12 5 0.0430
MF GO:0036094 small molecule binding 210 2.99 6 0.0490

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