MMP0540 MMP0540 Phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI)

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Methanococcus maripaludis S2

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Summary

Locus Tag Symbol Synonyms Product Protein Synonyms Start End Strand PubMed ID
MMP0540 MMP0540 purC purC, MMP0540 Phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI) Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) (SAICAR synthetase) 545004 545744 + 15466049

Regulatory Modules

Residual Expression Plot
mmp-bicluster_0112 0.28
mmp-bicluster_0143 0.30

XReference

Uniprot NCBI Gene NCBI Protein GI Number MicrobesOnline EnsemblBacteria InterPro EggNOG
Q6LZT3 2761961 NP_987660.1;WP_011170484.1; 45358103 532733 CAF30096 IPR013816, IPR028923, IPR001636, IPR018236 COG0152

Mutations

Transposon mutants

Title Insert TAG Module
MMP0540

Homology

Orthologues Paralogues

Functions

Catalytic Activity COG EC Description Protein families TIGR Roles
ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate. {ECO:0000256|HAMAP-Rule:MF_00137}. (F) COG152 | Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase (6.3.2.6) Phosphoribosylaminoimidazolesuccinocarboxamide synthase. SAICAR synthetase family Purines, pyrimidines, nucleosides, and nucleotides:Purine ribonucleotide biosynthesis

Essentiality

L1.Cm.T1 L1.Cm.T2 L1.cN.T1 L1.cN.T2 L1.T0 L2.Cm.T1 L2.Cm.T2 L2.cN.T1 L2.cN.T2 L2.T0
2 2 0 1 4 0 0 0 0 3

Product Synonyms

Product (LegacyBRC) Product (RefSeq)

Operon

Refseq

GI Number Accession Blast Conserved Domains
45358103 NP_987660.1 Run

GO Terms

String Network

Link to STRINGS STRINGS Network
MMP0540

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