Methanococcus maripaludis S2 Module 112 Residual: 0.28

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Summary

Residual: 0.28 Score: -18.3201 version: mmp_cmonkey_11_Oct_11

Members

MMP0540 Phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI)

Details for MMP0540 - Phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI)

GO Terms: GO:0006164, GO:0004639, GO:0005524

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0540

Tuberculist Genomic Region

MMP1308 Transaldolase (NCBI)

Details for MMP1308 - Transaldolase (NCBI)

GO Terms: GO:0005975, GO:0004801

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1308

Tuberculist Genomic Region

MMP0082 glutamate synthase; large subunit; archaeal subunit 3 (NCBI)

Details for MMP0082 - glutamate synthase; large subunit; archaeal subunit 3 (NCBI)

GO Terms: GO:0008152, GO:0016491

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0082

Tuberculist Genomic Region

MMP1426 Bifunctional dCTP deaminase/dUTP diphosphatase (NCBI)

Details for MMP1426 - Bifunctional dCTP deaminase/dUTP diphosphatase (NCBI)

GO Terms: GO:0006229, GO:0008829

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1426

Tuberculist Genomic Region

MMP0083 conserved archaeal protein (NCBI)

Details for MMP0083 - conserved archaeal protein (NCBI)

GO Terms: GO:0006118, GO:0009055, GO:0050454, GO:0051536

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0083

Tuberculist Genomic Region

MMP1427 Conserved Hypothetical Protein (NCBI)

Details for MMP1427 - Conserved Hypothetical Protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1427

Tuberculist Genomic Region

MMP0162 conserved hypothetical protein (NCBI)

Details for MMP0162 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0162

Tuberculist Genomic Region

MMP1437 DNA topoisomerase VI A (NCBI)

Details for MMP1437 - DNA topoisomerase VI A (NCBI)

GO Terms: GO:0006265, GO:0005694, GO:0005524, GO:0003918

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1437

Tuberculist Genomic Region

MMP0414 Threonyl-tRNA synthetase (NCBI)

Details for MMP0414 - Threonyl-tRNA synthetase (NCBI)

GO Terms: GO:0006435, GO:0005737, GO:0005524, GO:0004829

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0414

Tuberculist Genomic Region

MMP1583 S-adenosylmethionine decarboxylase related (NCBI)

Details for MMP1583 - S-adenosylmethionine decarboxylase related (NCBI)

GO Terms: GO:0004014

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1583

Tuberculist Genomic Region

MMP0704 ParA type ATPase (NCBI)

Details for MMP0704 - ParA type ATPase (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0704

Tuberculist Genomic Region

MMP1585 Arginase (NCBI)

Details for MMP1585 - Arginase (NCBI)

GO Terms: GO:0006596, GO:0046872, GO:0008783

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1585

Tuberculist Genomic Region

MMP0894 GMP synthase (glutamine-hydrolyzing). (NCBI)

Details for MMP0894 - GMP synthase (glutamine-hydrolyzing). (NCBI)

GO Terms: GO:0006177, GO:0009435, GO:0008033, GO:0005737, GO:0003922, GO:0005524, GO:0004808, GO:0003952

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0894

Tuberculist Genomic Region

MMP1615 Conserved hypothetical protein (NCBI)

Details for MMP1615 - Conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1615

Tuberculist Genomic Region

MMP1017 Aspartate kinase (NCBI)

Details for MMP1017 - Aspartate kinase (NCBI)

GO Terms: GO:0008652, GO:0016597, GO:0004072

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1017

Tuberculist Genomic Region

MMP1616 Aspartyl-tRNA synthetase (NCBI)

Details for MMP1616 - Aspartyl-tRNA synthetase (NCBI)

GO Terms: GO:0006422, GO:0005737, GO:0003676, GO:0004815, GO:0005524

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1616

Tuberculist Genomic Region

MMP1188 conserved hypothetical archaeal protein (NCBI)

Details for MMP1188 - conserved hypothetical archaeal protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1188

Tuberculist Genomic Region

MMP0081 glutamate synthase; large subunit; archaeal subunit 2 (NCBI)

Details for MMP0081 - glutamate synthase; large subunit; archaeal subunit 2 (NCBI)

GO Terms: GO:0006537, GO:0006118, GO:0006207, GO:0009342, GO:0004152, GO:0051536, GO:0004355, GO:0009055, GO:0016040

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0081

Tuberculist Genomic Region

MMP1306 conserved hypothetical protein (NCBI)

Details for MMP1306 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1306

Tuberculist Genomic Region

Displaying 1 - 19 of 19

Motifs

Motif 1: e-value: 420 e-value: 370

Module Plots

Regulation

Regulator Interaction Influence Weight Other Influences

MMP0907

predicted archaeal transcriptional regulator (NCBI)

MMP1646

conserved hypothetical archaeal protein (NCBI)
 up-regulates 0.74

MMP0907

MMP1646

MMP0637

Transcriptional regulator, ArsR family member (NCBI)
 up-regulates 0.43

MMP0637

MMP1467

conserved hypothetical protein (NCBI)

MMP1646

conserved hypothetical archaeal protein (NCBI)
 down-regulates -0.39

MMP1467

MMP1646

H2

 up-regulates 0.39

H2

GO Enrichment

Category: BP
Category GO ID GO Term Annotated Expected Significant p-value
BP GO:0072522 purine-containing compound biosynthetic ... 17 0.35 2 0.0400
BP GO:0072521 purine-containing compound metabolic pro... 19 0.40 2 0.0490
Category: MF
Category GO ID GO Term Annotated Expected Significant p-value
MF GO:0016810 hydrolase activity, acting on carbon-nit... 7 0.09 2 0.0031
MF GO:0043168 anion binding 196 2.54 6 0.0204
MF GO:0005524 ATP binding 147 1.90 5 0.0259
MF GO:0030554 adenyl nucleotide binding 149 1.93 5 0.0274
MF GO:0032559 adenyl ribonucleotide binding 149 1.93 5 0.0274
MF GO:0036094 small molecule binding 210 2.72 6 0.0287
MF GO:0043167 ion binding 220 2.85 6 0.0360
MF GO:0035639 purine ribonucleoside triphosphate bindi... 169 2.19 5 0.0456
MF GO:0001883 purine nucleoside binding 171 2.21 5 0.0478
MF GO:0017076 purine nucleotide binding 171 2.21 5 0.0478
MF GO:0032549 ribonucleoside binding 171 2.21 5 0.0478
MF GO:0032550 purine ribonucleoside binding 171 2.21 5 0.0478
MF GO:0032555 purine ribonucleotide binding 171 2.21 5 0.0478
MF GO:0001882 nucleoside binding 172 2.23 5 0.0489

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