Methanococcus maripaludis S2 Module 39 Residual: 0.44

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Summary

Residual: 0.44 Score: -11.2618 version: mmp_cmonkey_11_Oct_11

Members

MMP0087 Hydroxymethylglutaryl-coenzyme A reductase:3-hydroxy-3-methylglutaryl Coenzyme A reductase (NCBI)

Details for MMP0087 - Hydroxymethylglutaryl-coenzyme A reductase:3-hydroxy-3-methylglutaryl Coenzyme A reductase (NCBI)

GO Terms: GO:0015936, GO:0008299, GO:0016021, GO:0050661, GO:0004420

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0087

Tuberculist Genomic Region

MMP0965 formylmethanofuran dehydrogenase subunit E related protein (NCBI)

Details for MMP0965 - formylmethanofuran dehydrogenase subunit E related protein (NCBI)

GO Terms: GO:0005634, GO:0008270, GO:0018493

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0965

Tuberculist Genomic Region

MMP0088 Glutamyl-tRNA reductase (NCBI)

Details for MMP0088 - Glutamyl-tRNA reductase (NCBI)

GO Terms: GO:0033014, GO:0005737, GO:0050661, GO:0008883, GO:0004764

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0088

Tuberculist Genomic Region

MMP1176 putative iron transport system substrate-binding protein, N-term half (NCBI)

Details for MMP1176 - putative iron transport system substrate-binding protein, N-term half (NCBI)

GO Terms: GO:0006827, GO:0005381

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1176

Tuberculist Genomic Region

MMP0096 Aminotransferase (subgroup I) (NCBI)

Details for MMP0096 - Aminotransferase (subgroup I) (NCBI)

GO Terms: GO:0009058, GO:0016769, GO:0030170

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0096

Tuberculist Genomic Region

MMP1177 putative iron transport system substrate-binding protein, C-term half (NCBI)

Details for MMP1177 - putative iron transport system substrate-binding protein, C-term half (NCBI)

GO Terms: GO:0006827, GO:0005381

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1177

Tuberculist Genomic Region

MMP0164 Sirohydrochlorin cobaltochelatase (NCBI)

Details for MMP0164 - Sirohydrochlorin cobaltochelatase (NCBI)

GO Terms: GO:0009236, GO:0016852, GO:0046872

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0164

Tuberculist Genomic Region

MMP1178 iron transport Periplasmic binding protein (NCBI)

Details for MMP1178 - iron transport Periplasmic binding protein (NCBI)

GO Terms: GO:0006827, GO:0005381

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1178

Tuberculist Genomic Region

MMP0242 conserved hypothetical protein (NCBI)

Details for MMP0242 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0242

Tuberculist Genomic Region

MMP1181 iron transport system binding protein (NCBI)

Details for MMP1181 - iron transport system binding protein (NCBI)

GO Terms: GO:0006827, GO:0005381

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1181

Tuberculist Genomic Region

MMP0388 geranylgeranyl bacterial chlorophyll reductase related (NCBI)

Details for MMP0388 - geranylgeranyl bacterial chlorophyll reductase related (NCBI)

GO Terms: GO:0006118, GO:0006725, GO:0008033, GO:0004497, GO:0050660, GO:0004148

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0388

Tuberculist Genomic Region

MMP1182 Iron(III) dicitrate transport system permease protein (NCBI)

Details for MMP1182 - Iron(III) dicitrate transport system permease protein (NCBI)

GO Terms: GO:0006810, GO:0016020, GO:0005215

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1182

Tuberculist Genomic Region

MMP0644 Cation efflux protein (NCBI)

Details for MMP0644 - Cation efflux protein (NCBI)

GO Terms: GO:0006812, GO:0016020, GO:0008324

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0644

Tuberculist Genomic Region

MMP1183 iron ABC transporter ATPase subunit (NCBI)

Details for MMP1183 - iron ABC transporter ATPase subunit (NCBI)

GO Terms: GO:0005524, GO:0015623

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1183

Tuberculist Genomic Region

MMP0645 malate dehydrogenase, MDHII (NADP+-dependent) (NCBI)

Details for MMP0645 - malate dehydrogenase, MDHII (NADP+-dependent) (NCBI)

GO Terms: GO:0019642, GO:0006100, GO:0006108, GO:0005737, GO:0004459, GO:0030060

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0645

Tuberculist Genomic Region

MMP1437 DNA topoisomerase VI A (NCBI)

Details for MMP1437 - DNA topoisomerase VI A (NCBI)

GO Terms: GO:0006265, GO:0005694, GO:0005524, GO:0003918

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1437

Tuberculist Genomic Region

MMP0646 hypothetical protein (NCBI)

Details for MMP0646 - hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0646

Tuberculist Genomic Region

MMP1700 Na+/solute symporter (NCBI)

Details for MMP1700 - Na+/solute symporter (NCBI)

GO Terms: GO:0006810, GO:0016020, GO:0005215

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1700

Tuberculist Genomic Region

MMP0874 SAM (and some other nucleotide) binding motif (NCBI)

Details for MMP0874 - SAM (and some other nucleotide) binding motif (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0874

Tuberculist Genomic Region

MMP0389 ferredoxin (NCBI)

Details for MMP0389 - ferredoxin (NCBI)

GO Terms: GO:0006118, GO:0051536, GO:0009055

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0389

Tuberculist Genomic Region

MMP0875 S layer protein (NCBI)

Details for MMP0875 - S layer protein (NCBI)

GO Terms: GO:0005618

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0875

Tuberculist Genomic Region

MMP0629 conserved hypothetical archaeal protein (NCBI)

Details for MMP0629 - conserved hypothetical archaeal protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0629

Tuberculist Genomic Region

MMP0884 hypothetical protein (NCBI)

Details for MMP0884 - hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0884

Tuberculist Genomic Region

MMP0650 Acetohydroxyacid synthase large subunit (NCBI)

Details for MMP0650 - Acetohydroxyacid synthase large subunit (NCBI)

GO Terms: GO:0009082, GO:0000287, GO:0050660, GO:0003984, GO:0030976

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0650

Tuberculist Genomic Region

MMP0888 putative cobalt transport protein (NCBI)

Details for MMP0888 - putative cobalt transport protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0888

Tuberculist Genomic Region

MMP0651 Acetohydroxyacid synthase small subunit (NCBI)

Details for MMP0651 - Acetohydroxyacid synthase small subunit (NCBI)

GO Terms: GO:0009082, GO:0003984, GO:0016597

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0651

Tuberculist Genomic Region

MMP0889 Cobalamin (vitamin B12) biosynthesis CbiM protein (NCBI)

Details for MMP0889 - Cobalamin (vitamin B12) biosynthesis CbiM protein (NCBI)

GO Terms: GO:0009236, GO:0016021

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0889

Tuberculist Genomic Region

Displaying 1 - 27 of 27

Motifs

Motif 1: e-value: 4.2 e-value: 4900

Module Plots

Regulation

Regulator Interaction Influence Weight Other Influences

H2

 up-regulates 0.36

H2

MMP0480

conserved hypothetical protein (NCBI)

MMP1023

Transcriptional regulator, TetR Family Member (NCBI)
 up-regulates 0.22

MMP0480

MMP1023

MMP0465

conserved hypothetical archaeal protein (NCBI)
 down-regulates -0.15

MMP0465

MMP0791

Transcriptional regulator, TetR Family Member (NCBI)
 down-regulates -0.11

MMP0791

MMP0031

conserved hypothetical archeal protein (NCBI)

MMP0465

conserved hypothetical archaeal protein (NCBI)
 down-regulates -0.11

MMP0031

MMP0465

GO Enrichment

Category: MF
Category GO ID GO Term Annotated Expected Significant p-value
MF GO:0016744 transferase activity, transferring aldeh... 4 0.06 2 0.0011
MF GO:0050661 NADP binding 5 0.07 2 0.0018
MF GO:0050662 coenzyme binding 28 0.40 3 0.0058
MF GO:0048037 cofactor binding 32 0.46 3 0.0085
MF GO:0000166 nucleotide binding 200 2.85 6 0.0392
MF GO:1901265 nucleoside phosphate binding 200 2.85 6 0.0392
MF GO:0036094 small molecule binding 210 2.99 6 0.0491

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