Methanococcus maripaludis S2 Module 140 Residual: 0.37

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Summary

Residual: 0.37 Score: -12.4867 version: mmp_cmonkey_11_Oct_11

Members

MMP1357 ThiamineS (NCBI)

Details for MMP1357 - ThiamineS (NCBI)

GO Terms: GO:0006790

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1357

Tuberculist Genomic Region

MMP1353 conserved hypothetical protein (NCBI)

Details for MMP1353 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1353

Tuberculist Genomic Region

MMP0046 conserved hypothetical protein (NCBI)

Details for MMP0046 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0046

Tuberculist Genomic Region

MMP1438

Details for MMP1438 -

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1438

Tuberculist Genomic Region

MMP0074 Conserved hypothetical Archael protein (NCBI)

Details for MMP0074 - Conserved hypothetical Archael protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0074

Tuberculist Genomic Region

MMP1540 Conserved hypothetical Archael protein (NCBI)

Details for MMP1540 - Conserved hypothetical Archael protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1540

Tuberculist Genomic Region

MMP0106 conserved hypothetical protein (NCBI)

Details for MMP0106 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0106

Tuberculist Genomic Region

MMP0133 IMP dehydrogenase (NCBI)

Details for MMP0133 - IMP dehydrogenase (NCBI)

GO Terms: GO:0006177, GO:0003938

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0133

Tuberculist Genomic Region

MMP0210 Conserved hypothetical protein (NCBI)

Details for MMP0210 - Conserved hypothetical protein (NCBI)

GO Terms: GO:0016020

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0210

Tuberculist Genomic Region

MMP0224 glutamate-1-semialdehyde aminotransferase (NCBI)

Details for MMP0224 - glutamate-1-semialdehyde aminotransferase (NCBI)

GO Terms: GO:0033014, GO:0008483, GO:0030170, GO:0042286

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0224

Tuberculist Genomic Region

MMP0220 Sodium/proline symporter-related (NCBI)

Details for MMP0220 - Sodium/proline symporter-related (NCBI)

GO Terms: GO:0006810, GO:0016020, GO:0005215

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0220

Tuberculist Genomic Region

MMP0356 Glycosyl transferase, group 1 (NCBI)

Details for MMP0356 - Glycosyl transferase, group 1 (NCBI)

GO Terms: GO:0009058

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0356

Tuberculist Genomic Region

MMP0282 Phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI)

Details for MMP0282 - Phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI)

GO Terms: GO:0006189, GO:0009320, GO:0004638

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0282

Tuberculist Genomic Region

MMP0588 Diphthine synthase (NCBI)

Details for MMP0588 - Diphthine synthase (NCBI)

GO Terms: GO:0017183, GO:0004164

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0588

Tuberculist Genomic Region

MMP0346 2-hydroxyglutaryl-CoA dehydratase (Component D) related protein (NCBI)

Details for MMP0346 - 2-hydroxyglutaryl-CoA dehydratase (Component D) related protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0346

Tuberculist Genomic Region

MMP0707 Na+/H+ exchanger (NCBI)

Details for MMP0707 - Na+/H+ exchanger (NCBI)

GO Terms: GO:0006885, GO:0016021, GO:0015299

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0707

Tuberculist Genomic Region

MMP0530 hypothetical protein (NCBI)

Details for MMP0530 - hypothetical protein (NCBI)

GO Terms: GO:0016779

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0530

Tuberculist Genomic Region

MMP0878 Ribonuclease P-related protein (NCBI)

Details for MMP0878 - Ribonuclease P-related protein (NCBI)

GO Terms: GO:0008033, GO:0004526, GO:0004540

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0878

Tuberculist Genomic Region

MMP0531 hypothetical (NCBI)

Details for MMP0531 - hypothetical (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0531

Tuberculist Genomic Region

MMP0880 2-oxosuberate synthase, last step (NCBI)

Details for MMP0880 - 2-oxosuberate synthase, last step (NCBI)

GO Terms: GO:0009098, GO:0003862, GO:0051287

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0880

Tuberculist Genomic Region

MMP0550 similar to ABC-type amino acid transport system, periplasmic component (NCBI)

Details for MMP0550 - similar to ABC-type amino acid transport system, periplasmic component (NCBI)

GO Terms: GO:0006810, GO:0030288, GO:0005215

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0550

Tuberculist Genomic Region

MMP1106 hypothetical protein (NCBI)

Details for MMP1106 - hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1106

Tuberculist Genomic Region

MMP0554 SAM (and some other nucleotide) binding motif (NCBI)

Details for MMP0554 - SAM (and some other nucleotide) binding motif (NCBI)

GO Terms: GO:0008168

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0554

Tuberculist Genomic Region

MMP1326 DNA-directed RNA polymerase, subunit N (NCBI)

Details for MMP1326 - DNA-directed RNA polymerase, subunit N (NCBI)

GO Terms: GO:0045449, GO:0003902, GO:0003900, GO:0003677, GO:0003899, GO:0003901

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1326

Tuberculist Genomic Region

MMP0609 Peptidyl-tRNA hydrolase (NCBI)

Details for MMP0609 - Peptidyl-tRNA hydrolase (NCBI)

GO Terms: GO:0004045

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0609

Tuberculist Genomic Region

MMP1362 Glycoside hydrolase, family 1:DNA-directed RNA polymerase, beta subunit:ATP/GTP-binding site motif A (P-loop) (NCBI)

Details for MMP1362 - Glycoside hydrolase, family 1:DNA-directed RNA polymerase, beta subunit:ATP/GTP-binding site motif A (P-loop) (NCBI)

GO Terms: GO:0006350, GO:0005975, GO:0003902, GO:0003900, GO:0003677, GO:0003899, GO:0004553, GO:0003901

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1362

Tuberculist Genomic Region

MMP0705 UDP-N-acetylglucosamine 2-epimerase (NCBI)

Details for MMP0705 - UDP-N-acetylglucosamine 2-epimerase (NCBI)

GO Terms: GO:0006047, GO:0009103, GO:0008761

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0705

Tuberculist Genomic Region

MMP1425 Protein of unknown function DUF127 (NCBI)

Details for MMP1425 - Protein of unknown function DUF127 (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1425

Tuberculist Genomic Region

MMP0865 Aminotransferase (subgroup II) similar to Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (NCBI)

Details for MMP0865 - Aminotransferase (subgroup II) similar to Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (NCBI)

GO Terms: GO:0009102, GO:0004015, GO:0030170

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0865

Tuberculist Genomic Region

MMP1426 Bifunctional dCTP deaminase/dUTP diphosphatase (NCBI)

Details for MMP1426 - Bifunctional dCTP deaminase/dUTP diphosphatase (NCBI)

GO Terms: GO:0006229, GO:0008829

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1426

Tuberculist Genomic Region

MMP0999 conserved hypothetical membrane related protein (NCBI)

Details for MMP0999 - conserved hypothetical membrane related protein (NCBI)

GO Terms: GO:0006508, GO:0016020, GO:0008236

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0999

Tuberculist Genomic Region

MMP0319 precorrin-2 C-20 methyltransferase (NCBI)

Details for MMP0319 - precorrin-2 C-20 methyltransferase (NCBI)

GO Terms: GO:0009236, GO:0030788, GO:0043781

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0319

Tuberculist Genomic Region

MMP1068 K+-dependent Na+/Ca+ exchanger related-protein:Sodium/calcium exchanger membrane region (NCBI)

Details for MMP1068 - K+-dependent Na+/Ca+ exchanger related-protein:Sodium/calcium exchanger membrane region (NCBI)

GO Terms: GO:0016021

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1068

Tuberculist Genomic Region

MMP0541 Phosphoserine phosphatase (NCBI)

Details for MMP0541 - Phosphoserine phosphatase (NCBI)

GO Terms: GO:0006564, GO:0004647

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0541

Tuberculist Genomic Region

MMP1312 conserved hypothetical protein (NCBI)

Details for MMP1312 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1312

Tuberculist Genomic Region

MMP1356 conserved hypothetical protein (NCBI)

Details for MMP1356 - conserved hypothetical protein (NCBI)

GO Terms: GO:0009435, GO:0005737, GO:0003952, GO:0004808

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1356

Tuberculist Genomic Region

Displaying 1 - 36 of 36

Motifs

Motif 1: e-value: 0.011 e-value: 110

Module Plots

Regulation

Regulator Interaction Influence Weight Other Influences

MMP0033

LysR family member (NCBI)

H2

 up-regulates 0.38

MMP0033

H2

MMP0637

Transcriptional regulator, ArsR family member (NCBI)
 up-regulates 0.27

MMP0637

MMP0052

Conserved Hypothetical protein with 2 CBS domains (NCBI)

MMP0257

TATA-binding protein (TBP) (NCBI)
 down-regulates -0.15

MMP0052

MMP0257

MMP1467

conserved hypothetical protein (NCBI)

MMP1646

conserved hypothetical archaeal protein (NCBI)
 up-regulates 0.13

MMP1467

MMP1646

GO Enrichment

Category: MF
Category GO ID GO Term Annotated Expected Significant p-value
MF GO:0016740 transferase activity 70 1.18 4 0.0240
MF GO:0008168 methyltransferase activity 18 0.30 2 0.0340
MF GO:0016741 transferase activity, transferring one-c... 19 0.32 2 0.0380

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