39924 (TopoII_1) gyrB
Thalassiosira pseudonana

Genome Browser

Summary

Chromosome Product Transcript Start End Strand Short Name
39924 chr_3 (TopoII_1) gyrB 1143300 1146078 + gyrB

Synonyms

NCBI ID Ensembl Genomes exon ID
7451686 Thaps39924.4, Thaps39924.3, Thaps39924.2, Thaps39924.1

Hierarchical Clustering

Expression Profile Conditional Changes Cluster Dendrogram
Thaps_hclust_0231

Motif-Guided Biclusters

Normalized Mean Residue
Thaps_bicluster_0254
 0.29

Most Highly Correlated Transcripts

26492

PRK05385
0.9121

23336

SRP40_C superfamily
0.9038

39845

(DNA_TopoIV) PRK05560
0.9028

22985

WD40 superfamily
0.9004

33670

RNRR2
0.8997

11949

Nop14
0.8973

24123

fumC
0.8877

16947

DEXDc superfamily
0.8829

34596

WD40
0.8825

21245

MPP_superfamily superfamily
0.8819

Conserved Domains

Name CD Accession Definition Superfamily Bitscore E-Value From - To Hit Type PSSM ID
TopoII_Trans_DNA_gyrase TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type... cl02783 174.286 1.76E-50 366 - 490 specific 238419
TopoII_MutL_Trans superfamily MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-... - 174.286 1.76E-50 366 - 490 superfamily 261445
TOPRIM superfamily Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA,... - 214.441 1.53E-65 535 - 649 superfamily 260587
DNA_gyraseB_C superfamily DNA gyrase B subunit, carboxyl terminus; The amino terminus of eukaryotic and prokaryotic DNA... - 124.559 8.08E-34 682 - 744 superfamily 250273
DNA_gyraseB_C superfamily DNA gyrase B subunit, carboxyl terminus; The amino terminus of eukaryotic and prokaryotic DNA... - 124.559 8.08E-34 682 - 744 superfamily 250273
gyrB DNA gyrase subunit B; Validated - 930.658 0 88 - 758 multi-dom 235542

Homologs in Other Species

T. pseudonana P. tricornutum P. tricornutum DiatomCyc F. cylindrus Pseudo-nitzschia multiseries E. huxleyi C. reinhardtii A. thaliana P. sojae
Not available PHATRDRAFT_21316 PHATRDRAFT_21316 254096 324999 464775 Cre10.g440750.t1.2 AT5G04130.1 Not available

KEGG

KEGG description KEGG Pathway
Not available Not available

GO Terms

GO:0003677 GO:0003918 GO:0005524 GO:0006259 GO:0006265 GO:0003676 GO:0006304 -

GO:0003677

DNA binding

Details: 
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO Category: 
MF

GO:0003918

DNA topoisomerase type II (ATP-hydrolyzing) activity

Details: 
Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
GO Category: 
MF

GO:0005524

ATP binding

Details: 
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
GO Category: 
MF

GO:0006259

DNA metabolic process

Details: 
Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.
GO Category: 
BP

GO:0006265

DNA topological change

Details: 
The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number.
GO Category: 
BP

GO:0003676

nucleic acid binding

Details: 
Interacting selectively and non-covalently with any nucleic acid.
GO Category: 
MF

GO:0006304

DNA modification

Details: 
The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties.
GO Category: 
BP

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