Rv0667 DNA-directed RNA polymerase beta subunit (EC 2.7.7.6)

Rv0667 (DNA-directed RNA polymerase beta subunit (EC 2.7.7.6)) is predicted to be co-regulated in modules bicluster_0327 with residual 0.42 and bicluster_0354 with residual 0.44.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 440.00 and 980.00 for bicluster_0327 and 580.00 and 4,500.00 for bicluster_0354 respectively.

These modules are enriched for following go terms: monocarboxylic acid binding, protein tyrosine kinase activity, sulfur compound binding, protein kinase activity, amide binding .

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 11 - 14 of 14
ChipSeq TF Differential Expression Distance Expression pvalue Type
Arsenical resistance operon repressor
No 18 0.08 0.938694 Primary.TSS
Transcriptional regulator, TetR family
No -14 0.01 0.990218 Primary.TSS
putative RNA polymerase sigma factor
No -21 -0.01 0.987523 Primary.TSS
RNA polymerase sigma-54 factor RpoN
No 24 -0.15 0.503979 Primary.TSS
not assigned to any KEGG Pathway.
GO:0003899

DNA-directed RNA polymerase activity

DNA-directed RNA polymerase activity

Details: 
Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
GO Category: 
molecular_function
5
Total items in this category:  
GO:0005618

cell wall

cell wall

Details: 
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan.
GO Category: 
cellular_component
320
Total items in this category:  
GO:0005829

cytosol

cytosol

Details: 
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
GO Category: 
cellular_component
371
Total items in this category:  
GO:0005886

plasma membrane

plasma membrane

Details: 
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
GO Category: 
cellular_component
1284
Total items in this category:  
GO:0040007

growth

growth

Details: 
The increase in size or mass of an entire organism, a part of an organism or a cell.
GO Category: 
biological_process
621
Total items in this category:  
No TFOE experiment results were found
TRIP log2 fold abundance change
NA