Rv1353c Transcriptional regulator, TetR family

Rv1353c (Transcriptional regulator, TetR family) is predicted to be co-regulated in modules bicluster_0418 with residual 0.49 and bicluster_0511 with residual 0.52.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.00 and 7.60 for bicluster_0418 and 670.00 and 6,900.00 for bicluster_0511 respectively.

These modules are enriched for following go terms: phosphopantetheine binding, modified amino acid binding, amide binding, amino acid binding.

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 51 - 60 of 238
Gene Target Differential Expression Distance Expression pvalue Type
Lipoprotein LpqP
No -9 -0.19 0.545476 Primary.TSS
3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100)
No -48 -0.01 0.988009 CDS
LSU ribosomal protein L2p (L8e)
No -60 -0.07 0.894243 Primary.TSS
No 11 -0.58 0.0856425 CDS
Preprotein translocase secY subunit (TC 3.A.5.1.1)
No -65 -0.4 0.199971 Primary.TSS
Transcriptional regulator, MarR family
No 44 -0.35 0.551407 CDS
Adenylosuccinate lyase (EC 4.3.2.2)
Repressed -19 -1.68 0 Primary.TSS
Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
No -92 0.34 0.00559272 CDS
Repressed -14 -1.09 0.00000662 Primary.TSS
PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN
No -83 -0.1 0.823713 Internal.TSS
not assigned to any KEGG Pathway.
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 11.53 U
D3I 3 3 3.83 11.57 I
D3U 3 3 3.83 12.19 U
D5I 9 5 6.00 8.02 I
D5U 17 5 6.00 10.51 U
D7I 18 7 8.14 7.58 I
D7U 19 7 8.14 10.54 U
D14I 4 14 15.63 2.57 I
D14U 4 14 15.63 9.74 U
D17I 3 17 19.15 2.30 I
D17U 3 17 19.15 9.50 U
D21I 4 21 23.23 I
D21U 4 21 23.23 8.60 U
D24I 3 24 26.60 I
D24U 3 24 26.60 8.86 U
D28I 4 28 30.61 1.11 I
D28U 4 28 30.61 7.94 U