Rv2779c Transcriptional regulator, AsnC family

Rv2779c (Transcriptional regulator, AsnC family) is predicted to be co-regulated in modules bicluster_0487 with residual 0.48 and bicluster_0552 with residual 0.57.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.00 and 3.50 for bicluster_0487 and 0.00 and 0.00 for bicluster_0552 respectively.

These modules are enriched for following go terms: IMP biosynthetic process, 'de novo' IMP biosynthetic process, IMP metabolic process.

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 11 - 20 of 34
ChipSeq TF Differential Expression Distance Expression pvalue Type
transcriptional regulator, ArsR family
No 57 0.4 0.0740106 Internal.TSS
HTH-type transcriptional regulator
No 17 -0.26 0.538269 CDS
Histone protein Lsr2
No 44 0.1 0.890683 Internal.TSS
Transcriptional regulator, IclR family
No 38 0.13 0.895345 Internal.TSS
Transcriptional regulator, ArsR family
No -120 0.48 0.0815641 Internal.TSS
Transcriptional regulator, PadR family
No 69 -0.44 0.962221 Internal.TSS
Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system
No 1 0.39 0.370454 CDS
Transcriptional regulator, ArsR family
No 31 0.01 0.976366 CDS
putative two-component system response regulator
No 43 -0.71 0.0770693 Internal.TSS
Possible oxidoreductase subunit
No 25 0.24 0.634596 Internal.TSS
not assigned to any KEGG Pathway.
No TFOE experiment results were found
TRIP log2 fold abundance change
NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 13.93 U
D3I 3 3 3.83 13.92 I
D3U 3 3 3.83 14.82 U
D5I 9 5 6.00 13.72 I
D5U 17 5 6.00 13.44 U
D7I 18 7 8.14 14.10 I
D7U 19 7 8.14 13.49 U
D14I 4 14 15.63 14.83 I
D14U 4 14 15.63 13.71 U
D17I 3 17 19.15 14.78 I
D17U 3 17 19.15 13.39 U
D21I 4 21 23.23 14.89 I
D21U 4 21 23.23 13.65 U
D24I 3 24 26.60 14.83 I
D24U 3 24 26.60 13.19 U
D28I 4 28 30.61 14.99 I
D28U 4 28 30.61 13.36 U