Rv3153 NADH-ubiquinone oxidoreductase chain I (EC 184.108.40.206)
This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.03 and 0.07 for bicluster_0165 and 710.00 and 1,500.00 for bicluster_0257 respectively.
These modules are enriched for following go terms: phosphate-containing compound metabolic ..., phosphorus metabolic process, NAD binding phosphate-containing compound metabolic ..., phosphorus metabolic process.
This gene is found to be for growth on cholesterol.
Mutant available?: Yes
|BASS Score||Distance to Tuberculist Start Codon||Internal TSS||New Internal UTR||Re-Annotated Start||Tuberculist Annotated Start|
|Product (LegacyBRC)||Product (RefSeq)|
|NADH-quinone oxidoreductase subunit I||NADH dehydrogenase subunit I|
|2058||- - - - - -|
|BioCyc Gene Page||Cellular Overview Map|
NADH dehydrogenase (ubiquinone) activity
reports the log2 abundance fold change of each TFI strain, relative to no induction, in absence or presence of drug, averaged across experimental replicates. Also reported are the accompanying z-scores and two-sided t-test p-values for each TFI strain under each condition. Please refer to Ma et al., 2020, Nature Microbiology for more information.