Rv3219 WhiB-like transcription regulator

Rv3219 (WhiB-like transcription regulator) is predicted to be co-regulated in modules bicluster_0402 with residual 0.39 and bicluster_0475 with residual 0.40.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.00 and 650.00 for bicluster_0402 and 0.00 and 9.10 for bicluster_0475 respectively.

These modules are enriched for following go terms: fatty acid synthase activity.

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 11 - 20 of 23
Gene Target Differential Expression Distance Expression pvalue Type
PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN
No -35 -0.06 0.999923 Antisense.TSS
3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9)
No -25 0.07 0.999923 Primary.TSS
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit 1 / 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit 2
No 46 0.07 0.999923 Primary.TSS
No -5 0.32 0.999923 Antisense.TSS
No 7 0.05 0.999923 Primary.TSS
\Transcriptional regulator, CopG family\\\""
No -75 0.31 0.999923 Primary.TSS
No -93 0.49 0.999923 CDS
No -78 0.49 0.999923 Antisense.TSS
No -78 0.53 0.999923 Primary.TSS
SSU ribosomal protein S15p (S13e)
No -32 0.19 0.999923 Primary.TSS
Displaying 11 - 18 of 18
ChipSeq TF Differential Expression Distance Expression pvalue Type
Transcriptional regulator, IclR family
No 57 0.11 0.932186 Primary.TSS
Transcriptional regulatory protein
No -73 0.21 0.595109 Primary.TSS
Transcriptional regulator, ArsR family
Repressed 17 -0.86 0.000255765 Primary.TSS
WhiB-type transcription regulator
No -87 -0.26 0.999973 Primary.TSS
transcriptional regulator, ArsR family
Repressed -60 -0.61 0.00946718 Primary.TSS
Histone protein Lsr2
No 24 0.03 0.976694 Primary.TSS
putative two-component system response regulator
No -1 0.2 0.749769 Primary.TSS
Transcriptional regulator, ArsR family
No 31 0.37 0.339648 Primary.TSS
not assigned to any KEGG Pathway.
GO:0005515

protein binding

protein binding

Details: 
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
GO Category: 
molecular_function
135
Total items in this category:  
GO:0015035

protein disulfide oxidoreductase activity

protein disulfide oxidoreductase activity

Details: 
Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds.
GO Category: 
molecular_function
7
Total items in this category:  
GO:0042803

protein homodimerization activity

protein homodimerization activity

Details: 
Interacting selectively and non-covalently with an identical protein to form a homodimer.
GO Category: 
molecular_function
83
Total items in this category:  
GO:0047134

protein-disulfide reductase activity

protein-disulfide reductase activity

Details: 
Catalysis of the reaction: protein-dithiol + NAD(P)+ = protein-disulfide + NAD(P)H + H+.
GO Category: 
molecular_function
2
Total items in this category:  
No TFOE experiment results were found
TRIP log2 fold abundance change
NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 12.89 U
D3I 3 3 3.83 13.53 I
D3U 3 3 3.83 13.44 U
D5I 9 5 6.00 13.53 I
D5U 17 5 6.00 13.29 U
D7I 18 7 8.14 14.17 I
D7U 19 7 8.14 13.47 U
D14I 4 14 15.63 16.46 I
D14U 4 14 15.63 14.16 U
D17I 3 17 19.15 17.45 I
D17U 3 17 19.15 14.25 U
D21I 4 21 23.23 17.15 I
D21U 4 21 23.23 14.07 U
D24I 3 24 26.60 18.34 I
D24U 3 24 26.60 14.10 U
D28I 4 28 30.61 17.69 I
D28U 4 28 30.61 13.78 U