Publications

Filters: Www.seattlechildrens.org is research  [Clear All Filters]
2020
Nemeth J, Olson GS, Rothchild AC, et al. "Contained Mycobacterium tuberculosis infection induces concomitant and heterologous protection." PLoS Pathog. 2020;16(7):e1008655.
Rothchild AC, Mai D, Aderem A, Diercks AH. "Flow Cytometry Analysis and Fluorescence-activated Cell Sorting of Myeloid Cells from Lung and Bronchoalveolar Lavage Samples from -infected Mice." Bio Protoc. 2020;10(10).
Peters JS, Ismail N, Dippenaar A, et al. "Genetic Diversity in Clinical Isolates and Resulting Outcomes of Tuberculosis Infection and Disease." Annu Rev Genet. 2020.
Peterson EJR, Abidi AA, Arrieta-Ortiz ML, et al. "Intricate Genetic Programs Controlling Dormancy in Mycobacterium tuberculosis." Cell Rep. 2020;31(4):107577.
Rahil Z, Leylek R, Schürch CM, et al. "Landscape of coordinated immune responses to H1N1 challenge in humans." J Clin Invest. 2020;130(11):5800-5816.
Ma S, Morrison R, Hobbs SJ, et al. "Transcriptional regulator-induced phenotype screen reveals drug potentiators in Mycobacterium tuberculosis." Nat Microbiol. 2020.
Plumlee CR, Duffy FJ, Gern BH, et al. "Ultra-low Dose Aerosol Infection of Mice with Mycobacterium tuberculosis More Closely Models Human Tuberculosis." Cell Host Microbe. 2020.
2019
Rothchild AC, Olson GS, Nemeth J, et al. "Alveolar macrophages generate a noncanonical NRF2-driven transcriptional response in vivo." Sci Immunol. 2019;4(37).
Delahaye JL, Gern BH, Cohen SB, et al. "BCG-induced T cells shape Mycobacterium tuberculosis infection before reducing the bacterial burden." bioRxiv. 2019.
Delahaye JL, Gern BH, Cohen SB, et al. "Cutting Edge: Bacillus Calmette–Guérin–Induced T Cells Shape Mycobacterium tuberculosis Infection before Reducing the Bacterial Burden." The Journal of Immunology. 2019;203:807-812.
Adams KN, Verma AKumar, Gopalaswamy R, et al. "Diverse Clinical Isolates of Mycobacterium tuberculosis Develop Macrophage-Induced Rifampin Tolerance." The Journal of Infectious Diseases. 2019;219:1554-1558.
Duffy FJ, Weiner J, Hansen S, et al. "Immunometabolic Signatures Predict Risk of Progression to Active Tuberculosis and Disease Outcome." Front Immunol. 2019;10:527.
Peterson, JR E, Bailo R, Rothchild AC, et al. "Path-seq identifies an essential mycolate remodeling program for mycobacterial host adaptation." Molecular Systems Biology. 2019;15:e8584.
Ma S, Jaipalli S, Larkins-Ford J, et al. "Transcriptomic Signatures Predict Regulators of Drug Synergy and Clinical Regimen Efficacy against Tuberculosis." mBio. 2019;10(6).
2018
Cohen SB, Gern BH, Delahaye JL, et al. "Alveolar Macrophages Provide an Early Mycobacterium tuberculosis Niche and Initiate Dissemination." Cell Host Microbe. 2018;24(3):439-446.e4.
Cohen SB, Urdahl KB. "Going beyond gamma for TB protection." Nat Microbiol. 2018;3(11):1194-1195.
Hansen SG, Zak DE, Xu G, et al. "Prevention of tuberculosis in rhesus macaques by a cytomegalovirus-based vaccine." Nat. Med.. 2018;24(2):130-143.
Thompson EG, Shankar S, Gideon HP, et al. "Prospective Discrimination of Controllers From Progressors Early After Low-Dose Mycobacterium tuberculosis Infection of Cynomolgus Macaques using Blood RNA Signatures." J. Infect. Dis.. 2018;217(8):1318-1322.
2017
Moguche AO, Musvosvi M, Penn-Nicholson A, et al. "Antigen Availability Shapes T Cell Differentiation and Function during Tuberculosis." Cell Host Microbe. 2017;21(6):695-706.e5.
Boot M, van Winden VJC, Sparrius M, et al. "Cell envelope stress in mycobacteria is regulated by the novel signal transduction ATPase IniR in response to trehalose." PLoS Genet.. 2017;13(12):e1007131.
Nicod C, Banaei-Esfahani A, Collins BC. "Elucidation of host-pathogen protein-protein interactions to uncover mechanisms of host cell rewiring." Curr. Opin. Microbiol.. 2017;39:7-15.
Thompson EG, Du Y, Malherbe ST, et al. "Host blood RNA signatures predict the outcome of tuberculosis treatment." Tuberculosis (Edinb). 2017;107:48-58.
Scriba TJ, Penn-Nicholson A, Shankar S, et al. "Sequential inflammatory processes define human progression from M. tuberculosis infection to tuberculosis disease." PLoS Pathog.. 2017;13(11):e1006687.
Woodworth JS, Cohen SB, Moguche AO, et al. "Subunit vaccine H56/CAF01 induces a population of circulating CD4 T cells that traffic into the Mycobacterium tuberculosis-infected lung." Mucosal Immunol. 2017;10(2):555-564.
Banaei-Esfahani A, Nicod C, Aebersold R, Collins BC. "Systems proteomics approaches to study bacterial pathogens: application to Mycobacterium tuberculosis." Curr. Opin. Microbiol.. 2017;39:64-72.