P9WHK5 pyrH, Rv2883c, MTCY274.14c | MTB Network Portal

Summary

Source: Uniprot proteome:up000001584

Title	id	ORF names	Protein names	PubMed ID	Short	Synonyms	EnsemblBacteria
P9WHK5 PYRH_MYCTU	Rv2883c Uridylate kinase (EC 2.7.4.-)	MTCY274.14c	Uridylate kinase (UK) (EC 2.7.4.22) (Uridine monophosphate kinase) (UMP kinase) (UMPK)	9634230	pyrH	pyrH, Rv2883c, MTCY274.14c

Structure Details

Binding Site	Subcellular location
77 77 UMP, via amide nitrogen (By similarity)., 78 78 ATP, via amide nitrogen (By similarity)., 82 82 ATP (By similarity)., 97 97 UMP (By similarity)., 191 191 ATP, via amide nitrogen and carbonyl oxygen (By similarity)., 194 194 ATP (By similarity).	Cytoplasm (By similarity).

Domain/Family Details

InterPro	Pfam	ProDom	Region	Similarity	SUPFAM
	PF00696			Belongs to the UMP kinase family.	SSF53633

Domain/Family DBs

Gene3D	HAMAP	PANTHER	Pfam	PIRSF	PRINTS	ProDom	PROSITE	SMART	SUPFAM
3.40.1160.10,	MF_01220_B,		PF00696	PIRSF005650,					SSF53633

SSGCID Target Details

SSGCID ID

3D Details

PDB	Protein Model Portal

Pathway Details

EC number	KEGG KO	UniPathway
2.7.4.22		Pyrimidine metabolism, CTP biosynthesis via de novo pathway, UDP from UMP (UMPK route): step 1/1.

Phylogenetic

HOGENOM	KEGG KO	OMA	OrthoDB