33955 PkinaseThalassiosira pseudonana

Summary

	Chromosome	Product	Transcript Start	End	Strand	Short Name
33955	chr_4	Pkinase	914374	917006	-	Pkinase

Synonyms

NCBI ID	Ensembl Genomes exon ID
7447925	Thaps33955.3, Thaps33955.2, Thaps33955.1

Hierarchical Clustering

Expression Profile	Conditional Changes	Cluster Dendrogram	Discovered Potential cis-Regulatory Motifs
Thaps_hclust_0079

Motif-Guided Biclusters

	Normalized Mean Residue	Discovered Potential cis-Regulatory Motifs
Thaps_bicluster_0213	0.25	12000 47000

Most Highly Correlated Transcripts

6356 hypothetical protein 0.9358	20954 (Tp_CXC3) TCR 0.9357	7206 hypothetical protein 0.9317	bd1983 (bd1983) RecA-like_NTPases superfamily 0.9285	35387 (cdc2) PKc_like superfamily 0.9269	2267 hypothetical protein 0.9264
1908 hypothetical protein 0.9236	23522 DUF1032 superfamily 0.9201	8536 CDC6 0.9185	1622 AE_Prim_S 0.9184

Conserved Domains

Name	Definition	Superfamily	Bitscore	E-Value	From - To	Hit Type	PSSM ID
PKc	Catalytic domain of Protein Kinases; Protein Kinases (PKs), catalytic (c) domain. PKs catalyze the...	cl09925	170.88	1.83E-48	509 - 749	specific	173623
PKc_like superfamily	Protein Kinases, catalytic domain; The protein kinase superfamily is mainly composed of the...	-	170.88	1.83E-48	509 - 749	superfamily	263920
Pkinase	Protein kinase domain; Protein kinase domain.	-	172.431	1.63E-48	503 - 748	multi-dom	249558

Homologs in Other Species

T. pseudonana	P. tricornutum	P. tricornutum DiatomCyc	F. cylindrus	Pseudo-nitzschia multiseries	E. huxleyi	C. reinhardtii	A. thaliana	P. sojae
Not available		Not available	160166	251025	Not available	Cre07.g355250.t1.2	AT1G02970.1	345704

KEGG

KEGG description	KEGG Pathway
Not available	Not available

GO Terms

GO:0004672 GO:0005524 GO:0006468 GO:0004713 GO:0004674 GO:0004675 GO:0004676 GO:0004677 GO:0004679 GO:0004680 GO:0004681 GO:0004683 GO:0004686 GO:0004688 GO:0004689 GO:0004690 GO:0004692 GO:0004693 GO:0004694 GO:0004695 GO:0004696 GO:0004697 GO:0004698 GO:0004700 GO:0004701 GO:0004702 GO:0004703 GO:0004704 GO:0004705 GO:0004706 GO:0004707 GO:0004708 GO:0004709 GO:0004710 GO:0004711 GO:0004712 GO:0004714 GO:0004715 GO:0004716 GO:0004718 GO:0008338 GO:0008339 GO:0008349 GO:0008384 GO:0008443 GO:0008545 GO:0008607 GO:0008819 GO:0016307 GO:0016538 GO:0016773 GO:0016908 GO:0016909 GO:0018720 GO:0019199 GO:0019912 GO:0019914 GO:0035004 GO:0042556 GO:0042557 -

GO:0004672

protein kinase activity

Details:

Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.

GO Category:

GO:0005524

ATP binding

Details:

Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

GO Category:

GO:0006468

protein phosphorylation

Details:

The process of introducing a phosphate group on to a protein.

GO Category:

GO:0004713

protein tyrosine kinase activity

Details:

Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.

GO Category:

GO:0004674

protein serine/threonine kinase activity

Details:

Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

GO Category:

GO:0004675

transmembrane receptor protein serine/threonine kinase activity

Details:

Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

GO Category:

GO:0004676

3-phosphoinositide-dependent protein kinase activity

Details:

Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of a phosphatidylinositol-3-phosphate.

GO Category:

GO:0004677

DNA-dependent protein kinase activity

Details:

Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of DNA.

GO Category:

GO:0004679

AMP-activated protein kinase activity

Details:

Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of AMP.

GO Category:

GO:0004680

Details:

GO Category:

GO:0004681

Details:

GO Category:

GO:0004683

calmodulin-dependent protein kinase activity

Details:

Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. These reactions require the presence of calcium-bound calmodulin.

GO Category:

GO:0004686

elongation factor-2 kinase activity

Details:

Catalysis of the reaction: ATP + [elongation factor 2] = ADP + [elongation factor 2] phosphate.

GO Category:

GO:0004688

Details:

GO Category:

GO:0004689

phosphorylase kinase activity

Details:

Catalysis of the reaction: 4 ATP + 2 phosphorylase b = 4 ADP + phosphorylase a.

GO Category:

GO:0004690

cyclic nucleotide-dependent protein kinase activity

Details:

Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of a cyclic nucleotide.

GO Category:

GO:0004692

cGMP-dependent protein kinase activity

Details:

Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of cGMP.

GO Category:

GO:0004693

cyclin-dependent protein serine/threonine kinase activity

Details:

Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).

GO Category:

GO:0004694

eukaryotic translation initiation factor 2alpha kinase activity

Details:

Catalysis of the reaction: ATP + [eukaryotic translation initiation factor 2 alpha subunit] = ADP + [eukaryotic translation initiation factor 2 alpha subunit] phosphate.

GO Category:

GO:0004695

Details:

GO Category:

GO:0004696

Details:

GO Category:

GO:0004697

protein kinase C activity

Details:

Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol.

GO Category:

GO:0004698

calcium-dependent protein kinase C activity

Details:

Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol and calcium.

GO Category:

GO:0004700

Details:

GO Category:

GO:0004701

Details:

GO Category:

GO:0004702

receptor signaling protein serine/threonine kinase activity

Details:

Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

GO Category:

GO:0004703

G-protein coupled receptor kinase activity

Details:

Catalysis of the reaction: ATP + G-protein coupled receptor = ADP + G-protein coupled receptor phosphate.

GO Category:

GO:0004704

NF-kappaB-inducing kinase activity

Details:

Catalysis of the phosphorylation of the alpha or beta subunit of the inhibitor of kappaB kinase complex (IKK).

GO Category:

GO:0004705

JUN kinase activity

Details:

Catalysis of the reaction: JUN + ATP = JUN phosphate + ADP. This reaction is the phosphorylation and activation of members of the JUN family, a gene family that encodes nuclear transcription factors.

GO Category:

GO:0004706

JUN kinase kinase kinase activity

Details:

Catalysis of the reaction: JNKK + ATP = JNKK phosphate + ADP. This reaction is the phosphorylation and activation of JUN kinase kinases (JNKKs).

GO Category:

GO:0004707

MAP kinase activity

Details:

Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli.

GO Category:

GO:0004708

MAP kinase kinase activity

Details:

Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate.

GO Category:

GO:0004709

MAP kinase kinase kinase activity

Details:

Catalysis of the phosphorylation and activation of a MAP kinase kinase; each MAP kinase kinase can be phosphorylated by any of several MAP kinase kinase kinases.

GO Category:

GO:0004710

Details:

GO Category:

GO:0004711

ribosomal protein S6 kinase activity

Details:

Catalysis of the reaction: ribosomal protein S6 + ATP = ribosomal protein S6 phosphate + ATP.

GO Category:

GO:0004712

protein serine/threonine/tyrosine kinase activity

Details:

Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; ATP + a protein threonine = ADP + protein threonine phosphate; and ATP + a protein tyrosine = ADP + protein tyrosine phosphate.

GO Category:

GO:0004714

transmembrane receptor protein tyrosine kinase activity

Details:

Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.

GO Category:

GO:0004715

non-membrane spanning protein tyrosine kinase activity

Details:

Catalysis of the reaction: ATP + a non-membrane spanning protein L-tyrosine = ADP + a non-membrane spanning protein L-tyrosine phosphate.

GO Category:

GO:0004716

receptor signaling protein tyrosine kinase activity

Details:

Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.

GO Category:

GO:0004718

Details:

GO Category:

GO:0008338

Details:

GO Category:

GO:0008339

Details:

GO Category:

GO:0008349

MAP kinase kinase kinase kinase activity

Details:

Catalysis of the phosphorylation of serine and threonine residues in a mitogen-activated protein kinase kinase kinase (MAPKKK), resulting in activation of MAPKKK. MAPKKK signaling pathways relay, amplify and integrate signals from the plasma membrane to the nucleus in response to a diverse range of extracellular stimuli.

GO Category:

GO:0008384

IkappaB kinase activity

Details:

Catalysis of the reaction: ATP + IkappaB protein = ADP + IkappaB phosphoprotein.

GO Category:

GO:0008443

phosphofructokinase activity

Details:

Catalysis of the transfer of a phosphate group, usually from ATP, to a fructose substrate molecule.

GO Category:

GO:0008545

JUN kinase kinase activity

Details:

Catalysis of the phosphorylation of tyrosine and threonine residues in a c-Jun NH2-terminal kinase (JNK), a member of a subgroup of mitogen-activated protein kinases (MAPKs), which signal in response to cytokines and exposure to environmental stress. JUN kinase kinase (JNKK) is a dual-specificity protein kinase kinase and requires activation by a serine/threonine kinase JUN kinase kinase kinase.

GO Category:

GO:0008607

phosphorylase kinase regulator activity

Details:

Modulation of the activity of the enzyme phosphorylase kinase.

GO Category:

GO:0008819

cobinamide kinase activity

Details:

Catalysis of the reaction: cobinamide + ATP = cobinamide phosphate + ADP. This reaction is the phosphorylation of the hydroxyl group of the 1-amino-2-propanol residue of cobinamide, in the presence of ATP, to form cobinamide phosphate.

GO Category:

GO:0016307

phosphatidylinositol phosphate kinase activity

Details:

Catalysis of the reaction: ATP + a phosphatidylinositol phosphate = ADP + a phosphatidylinositol bisphosphate.

GO Category:

GO:0016538

cyclin-dependent protein serine/threonine kinase regulator activity

Details:

Modulates the activity of a cyclin-dependent protein serine/threonine kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins.

GO Category:

GO:0016773

phosphotransferase activity, alcohol group as acceptor

Details:

Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor).

GO Category:

GO:0016908

Details:

GO Category:

GO:0016909

SAP kinase activity

Details:

Catalysis of the phosphorylation of proteins. A family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. Strongly activated by stress signals such as heat or osmotic shock, DNA-damaging agents, inhibitors of protein synthesis and pro-inflammatory cytokines.

GO Category:

GO:0018720

phenol kinase activity

Details:

Catalysis of the reaction: phenol + X-HPO3- = XH + phenylphosphate.

GO Category:

GO:0019199

transmembrane receptor protein kinase activity

Details:

Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP.

GO Category:

GO:0019912

cyclin-dependent protein kinase activating kinase activity

Details:

Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; increases the activity of a cyclin-dependent protein kinase (CDK).

GO Category:

GO:0019914

cyclin-dependent protein kinase activating kinase regulator activity

Details:

Modulation of the activity of the enzyme cyclin-dependent protein kinase activating kinase.

GO Category:

GO:0035004

phosphatidylinositol 3-kinase activity

Details:

Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol 3-phosphate. This reaction is the addition of a phosphate group to phosphatidylinositol or one of its phosphorylated derivatives at the 3' position of the inositol ring.

GO Category:

GO:0042556

eukaryotic elongation factor-2 kinase regulator activity

Details:

Modulates the activity of the enzyme eukaryotic elongation factor-2 kinase.

GO Category:

GO:0042557

eukaryotic elongation factor-2 kinase activator activity

Details:

Increases the activity of the enzyme eukaryotic elongation factor-2 kinase.

GO Category: