18190 P4Hc
Thalassiosira pseudonana

Genome Browser

Summary

Chromosome Product Transcript Start End Strand Short Name
18190 chr_8 P4Hc 355524 357461 - P4Hc

Synonyms

NCBI ID Ensembl Genomes exon ID
7445555 Thaps18190.1

Hierarchical Clustering

Expression Profile Conditional Changes Cluster Dendrogram
Thaps_hclust_0043

Motif-Guided Biclusters

Normalized Mean Residue
Thaps_bicluster_0033
 0.48

Most Highly Correlated Transcripts

bd1221

(bd1221) recQ_fam
0.9008

37549

Ribosomal_S18
0.8859

36007

Aldolase_II superfamily
0.8843

25708

hypothetical protein
0.879

35136

NA
0.8645

bd1133

(bd1133) ATM1
0.864

21723

DnaJ
0.859

31150

rpsI
0.8589

25279

TCP1_zeta
0.8531

36366

Ape1-like_AP-endo
0.8528

Conserved Domains

Name CD Accession Definition Superfamily Bitscore E-Value From - To Hit Type PSSM ID
P4Hc Prolyl 4-hydroxylase alpha subunit homologues; Mammalian enzymes catalyse hydroxylation of collagen... cl17304 83.9766 1.15E-18 415 - 583 specific 214780
2OG-FeII_Oxy_3 superfamily 2OG-Fe(II) oxygenase superfamily; This family contains members of the 2-oxoglutarate (2OG) and Fe(... - 83.9766 1.15E-18 415 - 583 superfamily 266616

Homologs in Other Species

T. pseudonana P. tricornutum P. tricornutum DiatomCyc F. cylindrus Pseudo-nitzschia multiseries E. huxleyi C. reinhardtii A. thaliana P. sojae
Not available PHATRDRAFT_5156 PHATRDRAFT_5156 153731 195808 444384 Cre08.g379950.t1.1 Not available Not available

KEGG

KEGG description KEGG Pathway
Metabolic pathways map01100

GO Terms

GO:0016706 GO:0019538 GO:0004656 GO:0016222 -

GO:0016706

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors

Details: 
Catalysis of the reaction: A + 2-oxoglutarate + O2 = B + succinate + CO2. This is an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and one atom of oxygen is incorporated into each donor.
GO Category: 
MF

GO:0019538

protein metabolic process

Details: 
The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
GO Category: 
BP

GO:0004656

procollagen-proline 4-dioxygenase activity

Details: 
Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2.
GO Category: 
MF

GO:0016222

procollagen-proline 4-dioxygenase complex

Details: 
A protein complex that catalyzes the formation of procollagen trans-4-hydroxy-L-proline and succinate from procollagen L-proline and 2-oxoglutarate, requiring Fe2+ and ascorbate. Contains two alpha subunits that contribute to most parts of the catalytic sites, and two beta subunits that are identical to protein-disulfide isomerase.
GO Category: 
CC

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