261937 ATP-grasp_4 superfamilyThalassiosira pseudonana

Summary

	Chromosome	Product	Transcript Start	End	Strand	Short Name
261937	chr_3	ATP-grasp_4 superfamily	2048183	2050293	+	ATP-grasp_4 superfamily

Synonyms

NCBI ID	Ensembl Genomes exon ID
7445383	Thaps261937.1, Thaps261937.3, Thaps261937.2

Hierarchical Clustering

Expression Profile	Conditional Changes	Cluster Dendrogram	Discovered Potential cis-Regulatory Motifs
Thaps_hclust_0236

Most Highly Correlated Transcripts

30701 PRK05279 0.9266	261400 NA 0.9197	20978 hypothetical protein 0.913	41655 Chloroa_b-bind 0.9112	268896 DnaQ_like_exo superfamily 0.9067	40704 WD40 0.9064
19059 SynMuv_product superfamily 0.901	33895 GlcD 0.8994	38736 S_TKc 0.8959	263361 CHD 0.8949

Conserved Domains

Name	CD Accession	Definition	Superfamily	Bitscore	E-Value	From - To	Hit Type	PSSM ID
ATP-grasp_4 superfamily		ATP-grasp domain; This family includes a diverse set of enzymes that possess ATP-dependent...	-	206.345	5.49E-61	254 - 554	superfamily	266590

Homologs in Other Species

T. pseudonana	P. tricornutum	P. tricornutum DiatomCyc	F. cylindrus	Pseudo-nitzschia multiseries	E. huxleyi	C. reinhardtii	A. thaliana	P. sojae
Not available	PHATRDRAFT_39499	PHATRDRAFT_39499	263442	154592	Not available	Cre01.g018400.t1.1	AT4G08170.2	Not available

KEGG

KEGG description	KEGG Pathway
Phosphatidylinositol signaling system	map04070

GO Terms

GO:0004675 GO:0004676 GO:0004677 GO:0004679 GO:0004680 GO:0004681 GO:0004683 GO:0004686 GO:0004688 GO:0004689 GO:0004690 GO:0004692 GO:0004693 GO:0004694 GO:0004695 GO:0004696 GO:0004697 GO:0004698 GO:0004700 GO:0004701 GO:0004702 GO:0004703 GO:0004704 GO:0004705 GO:0004706 GO:0004707 GO:0004708 GO:0004709 GO:0004710 GO:0004711 GO:0004712 GO:0004714 GO:0004715 GO:0004716 GO:0004718 GO:0008338 GO:0008339 GO:0008349 GO:0008384 GO:0008443 GO:0008545 GO:0008607 GO:0008819 GO:0016307 GO:0016538 GO:0016773 GO:0016908 GO:0016909 GO:0018720 GO:0019199 GO:0019912 GO:0019914 GO:0035004 GO:0042556 GO:0042557 -

GO:0004675

transmembrane receptor protein serine/threonine kinase activity

Details:

Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

GO Category:

GO:0004676

3-phosphoinositide-dependent protein kinase activity

Details:

Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of a phosphatidylinositol-3-phosphate.

GO Category:

GO:0004677

DNA-dependent protein kinase activity

Details:

Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of DNA.

GO Category:

GO:0004679

AMP-activated protein kinase activity

Details:

Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of AMP.

GO Category:

GO:0004680

Details:

GO Category:

GO:0004681

Details:

GO Category:

GO:0004683

calmodulin-dependent protein kinase activity

Details:

Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. These reactions require the presence of calcium-bound calmodulin.

GO Category:

GO:0004686

elongation factor-2 kinase activity

Details:

Catalysis of the reaction: ATP + [elongation factor 2] = ADP + [elongation factor 2] phosphate.

GO Category:

GO:0004688

Details:

GO Category:

GO:0004689

phosphorylase kinase activity

Details:

Catalysis of the reaction: 4 ATP + 2 phosphorylase b = 4 ADP + phosphorylase a.

GO Category:

GO:0004690

cyclic nucleotide-dependent protein kinase activity

Details:

Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of a cyclic nucleotide.

GO Category:

GO:0004692

cGMP-dependent protein kinase activity

Details:

Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of cGMP.

GO Category:

GO:0004693

cyclin-dependent protein serine/threonine kinase activity

Details:

Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).

GO Category:

GO:0004694

eukaryotic translation initiation factor 2alpha kinase activity

Details:

Catalysis of the reaction: ATP + [eukaryotic translation initiation factor 2 alpha subunit] = ADP + [eukaryotic translation initiation factor 2 alpha subunit] phosphate.

GO Category:

GO:0004695

Details:

GO Category:

GO:0004696

Details:

GO Category:

GO:0004697

protein kinase C activity

Details:

Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol.

GO Category:

GO:0004698

calcium-dependent protein kinase C activity

Details:

Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol and calcium.

GO Category:

GO:0004700

Details:

GO Category:

GO:0004701

Details:

GO Category:

GO:0004702

receptor signaling protein serine/threonine kinase activity

Details:

Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

GO Category:

GO:0004703

G-protein coupled receptor kinase activity

Details:

Catalysis of the reaction: ATP + G-protein coupled receptor = ADP + G-protein coupled receptor phosphate.

GO Category:

GO:0004704

NF-kappaB-inducing kinase activity

Details:

Catalysis of the phosphorylation of the alpha or beta subunit of the inhibitor of kappaB kinase complex (IKK).

GO Category:

GO:0004705

JUN kinase activity

Details:

Catalysis of the reaction: JUN + ATP = JUN phosphate + ADP. This reaction is the phosphorylation and activation of members of the JUN family, a gene family that encodes nuclear transcription factors.

GO Category:

GO:0004706

JUN kinase kinase kinase activity

Details:

Catalysis of the reaction: JNKK + ATP = JNKK phosphate + ADP. This reaction is the phosphorylation and activation of JUN kinase kinases (JNKKs).

GO Category:

GO:0004707

MAP kinase activity

Details:

Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli.

GO Category:

GO:0004708

MAP kinase kinase activity

Details:

Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate.

GO Category:

GO:0004709

MAP kinase kinase kinase activity

Details:

Catalysis of the phosphorylation and activation of a MAP kinase kinase; each MAP kinase kinase can be phosphorylated by any of several MAP kinase kinase kinases.

GO Category:

GO:0004710

Details:

GO Category:

GO:0004711

ribosomal protein S6 kinase activity

Details:

Catalysis of the reaction: ribosomal protein S6 + ATP = ribosomal protein S6 phosphate + ATP.

GO Category:

GO:0004712

protein serine/threonine/tyrosine kinase activity

Details:

Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; ATP + a protein threonine = ADP + protein threonine phosphate; and ATP + a protein tyrosine = ADP + protein tyrosine phosphate.

GO Category:

GO:0004714

transmembrane receptor protein tyrosine kinase activity

Details:

Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.

GO Category:

GO:0004715

non-membrane spanning protein tyrosine kinase activity

Details:

Catalysis of the reaction: ATP + a non-membrane spanning protein L-tyrosine = ADP + a non-membrane spanning protein L-tyrosine phosphate.

GO Category:

GO:0004716

receptor signaling protein tyrosine kinase activity

Details:

Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.

GO Category:

GO:0004718

Details:

GO Category:

GO:0008338

Details:

GO Category:

GO:0008339

Details:

GO Category:

GO:0008349

MAP kinase kinase kinase kinase activity

Details:

Catalysis of the phosphorylation of serine and threonine residues in a mitogen-activated protein kinase kinase kinase (MAPKKK), resulting in activation of MAPKKK. MAPKKK signaling pathways relay, amplify and integrate signals from the plasma membrane to the nucleus in response to a diverse range of extracellular stimuli.

GO Category:

GO:0008384

IkappaB kinase activity

Details:

Catalysis of the reaction: ATP + IkappaB protein = ADP + IkappaB phosphoprotein.

GO Category:

GO:0008443

phosphofructokinase activity

Details:

Catalysis of the transfer of a phosphate group, usually from ATP, to a fructose substrate molecule.

GO Category:

GO:0008545

JUN kinase kinase activity

Details:

Catalysis of the phosphorylation of tyrosine and threonine residues in a c-Jun NH2-terminal kinase (JNK), a member of a subgroup of mitogen-activated protein kinases (MAPKs), which signal in response to cytokines and exposure to environmental stress. JUN kinase kinase (JNKK) is a dual-specificity protein kinase kinase and requires activation by a serine/threonine kinase JUN kinase kinase kinase.

GO Category:

GO:0008607

phosphorylase kinase regulator activity

Details:

Modulation of the activity of the enzyme phosphorylase kinase.

GO Category:

GO:0008819

cobinamide kinase activity

Details:

Catalysis of the reaction: cobinamide + ATP = cobinamide phosphate + ADP. This reaction is the phosphorylation of the hydroxyl group of the 1-amino-2-propanol residue of cobinamide, in the presence of ATP, to form cobinamide phosphate.

GO Category:

GO:0016307

phosphatidylinositol phosphate kinase activity

Details:

Catalysis of the reaction: ATP + a phosphatidylinositol phosphate = ADP + a phosphatidylinositol bisphosphate.

GO Category:

GO:0016538

cyclin-dependent protein serine/threonine kinase regulator activity

Details:

Modulates the activity of a cyclin-dependent protein serine/threonine kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins.

GO Category:

GO:0016773

phosphotransferase activity, alcohol group as acceptor

Details:

Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor).

GO Category:

GO:0016908

Details:

GO Category:

GO:0016909

SAP kinase activity

Details:

Catalysis of the phosphorylation of proteins. A family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. Strongly activated by stress signals such as heat or osmotic shock, DNA-damaging agents, inhibitors of protein synthesis and pro-inflammatory cytokines.

GO Category:

GO:0018720

phenol kinase activity

Details:

Catalysis of the reaction: phenol + X-HPO3- = XH + phenylphosphate.

GO Category:

GO:0019199

transmembrane receptor protein kinase activity

Details:

Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP.

GO Category:

GO:0019912

cyclin-dependent protein kinase activating kinase activity

Details:

Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; increases the activity of a cyclin-dependent protein kinase (CDK).

GO Category:

GO:0019914

cyclin-dependent protein kinase activating kinase regulator activity

Details:

Modulation of the activity of the enzyme cyclin-dependent protein kinase activating kinase.

GO Category:

GO:0035004

phosphatidylinositol 3-kinase activity

Details:

Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol 3-phosphate. This reaction is the addition of a phosphate group to phosphatidylinositol or one of its phosphorylated derivatives at the 3' position of the inositol ring.

GO Category:

GO:0042556

eukaryotic elongation factor-2 kinase regulator activity

Details:

Modulates the activity of the enzyme eukaryotic elongation factor-2 kinase.

GO Category:

GO:0042557

eukaryotic elongation factor-2 kinase activator activity

Details:

Increases the activity of the enzyme eukaryotic elongation factor-2 kinase.

GO Category: