PITA_54 megaCluster: 7 Residual: 0.17 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_54	7	0.17	15	0	0.949064	0

Members

Displaying 1 - 37 of 37

100504663 autophagy related 14 Details for mCG_6911 - autophagy related 14 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100504663 Tuberculist Genomic Region	100972 RAB28, member RAS oncogene family Details for - - RAB28, member RAS oncogene family GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100972 Tuberculist Genomic Region
106633 intraflagellar transport 140 Details for - - intraflagellar transport 140 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 106633 Tuberculist Genomic Region	15356 3-hydroxy-3-methylglutaryl-Coenzyme A lyase Details for RP23-161N17.7 - 3-hydroxy-3-methylglutaryl-Coenzyme A lyase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15356 Tuberculist Genomic Region
15468 protein arginine N-methyltransferase 2 Details for - - protein arginine N-methyltransferase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15468 Tuberculist Genomic Region	209416 G patch domain and KOW motifs Details for RP23-109E24.1 - G patch domain and KOW motifs GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 209416 Tuberculist Genomic Region
212647 aldehyde dehydrogenase 4 family, member A1 Details for RP23-334I5.1 - aldehyde dehydrogenase 4 family, member A1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 212647 Tuberculist Genomic Region	217827 nrde-2 necessary for RNA interference, domain containing Details for - - nrde-2 necessary for RNA interference, domain containing GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 217827 Tuberculist Genomic Region
22697 zinc finger and SCAN domain containing 21 Details for - - zinc finger and SCAN domain containing 21 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22697 Tuberculist Genomic Region	236193 zinc finger protein 709 Details for - - zinc finger protein 709 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 236193 Tuberculist Genomic Region
53415 HIV-1 tat interactive protein 2, homolog (human) Details for - - HIV-1 tat interactive protein 2, homolog (human) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 53415 Tuberculist Genomic Region	57279 solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20 Details for - - solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 57279 Tuberculist Genomic Region
57895 coiled-coil domain containing 126 Details for - - coiled-coil domain containing 126 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 57895 Tuberculist Genomic Region	67608 nuclear prelamin A recognition factor Details for RP23-349B15.5 - nuclear prelamin A recognition factor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67608 Tuberculist Genomic Region
72284 oral cancer overexpressed 1 Details for - - oral cancer overexpressed 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72284 Tuberculist Genomic Region	72320 RIKEN cDNA 2510003E04 gene Details for - - RIKEN cDNA 2510003E04 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72320 Tuberculist Genomic Region
74044 transcription termination factor, RNA polymerase II Details for DN-358O3.2 - transcription termination factor, RNA polymerase II GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74044 Tuberculist Genomic Region	100855 TBC1 domain family, member 14 Details for - - TBC1 domain family, member 14 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100855 Tuberculist Genomic Region
11883 arylsulfatase A Details for - - arylsulfatase A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11883 Tuberculist Genomic Region	227298 family with sequence similarity 134, member A Details for - - family with sequence similarity 134, member A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 227298 Tuberculist Genomic Region
229211 acyl-Coenzyme A dehydrogenase family, member 9 Details for - - acyl-Coenzyme A dehydrogenase family, member 9 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 229211 Tuberculist Genomic Region	56484 forkhead box O3 Details for - - forkhead box O3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56484 Tuberculist Genomic Region
70207 translational activator of mitochondrially encoded cytochrome c oxidase I Details for RP23-81G14.4 - translational activator of mitochondrially encoded cytochrome c oxidase I GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70207 Tuberculist Genomic Region	71743 Coenzyme A synthase Details for RP23-440M18.3 - Coenzyme A synthase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71743 Tuberculist Genomic Region
97541 glutaminyl-tRNA synthetase Details for - - glutaminyl-tRNA synthetase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 97541 Tuberculist Genomic Region	104112 ATP citrate lyase Details for RP23-392I3.9 - ATP citrate lyase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 104112 Tuberculist Genomic Region
12039 branched chain ketoacid dehydrogenase E1, alpha polypeptide Details for - - branched chain ketoacid dehydrogenase E1, alpha polypeptide GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12039 Tuberculist Genomic Region	227620 UDP-N-acteylglucosamine pyrophosphorylase 1-like 1 Details for RP23-47P18.3 - UDP-N-acteylglucosamine pyrophosphorylase 1-like 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 227620 Tuberculist Genomic Region
230514 leptin receptor overlapping transcript Details for RP23-31K16.1 - leptin receptor overlapping transcript GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 230514 Tuberculist Genomic Region	18415 heat shock protein 4 like Details for - - heat shock protein 4 like GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18415 Tuberculist Genomic Region
226646 NADH dehydrogenase (ubiquinone) Fe-S protein 2 Details for - - NADH dehydrogenase (ubiquinone) Fe-S protein 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 226646 Tuberculist Genomic Region	233056 zinc finger protein 790 Details for - - zinc finger protein 790 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 233056 Tuberculist Genomic Region
56357 isovaleryl coenzyme A dehydrogenase Details for RP23-172B16.1 - isovaleryl coenzyme A dehydrogenase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56357 Tuberculist Genomic Region	68839 ankyrin repeat domain 46 Details for - - ankyrin repeat domain 46 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68839 Tuberculist Genomic Region
73658 spinster homolog 1 Details for - - spinster homolog 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 73658 Tuberculist Genomic Region	26889 ceroid-lipofuscinosis, neuronal 8 Details for - - ceroid-lipofuscinosis, neuronal 8 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26889 Tuberculist Genomic Region
69596 adaptor-related protein 5 complex, sigma 1 subunit Details for RP23-387C21.2 - adaptor-related protein 5 complex, sigma 1 subunit GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69596 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
FOXB1_forkhead_full_monomeric_9_1	0.135135	0.0000709

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.000005	AARAAAAMAAAA	NA	240	AGGGGCGGGGCC	Klf4_MA0039.2, SP1_MA0079.2, SP1_MA0079.1, V$SP1_Q6_01_M00931, V$SP4_Q5_M01273, V$SP1_Q6_M00196, V$SP1_Q4_01_M00932, V$KLF7_03_M02773, V$SP1_02_M01303, V$GC_01_M00255, V$SP1_Q2_01_M00933, V$MAZR_01_M00491, V$SP1_03_M02281, V$GKLF_02_M01588, V$CKROX_Q2_M01175, V$ZFP281_01_M01597, V$SP1_01_M00008, V$UF1H3BETA_Q6_M01068, V$BCL6B_04_M02844, V$SP2_01_M01783, V$MAZ_Q6_M00649, V$E2F3_Q6_M02089, V$SP4_03_M02810, V$ZFP281_04_M02831, V$SMAD4_04_M02898, V$ZFP410_04_M02936, V$CACD_01_M01113, V$ETF_Q6_M00695, V$CACBINDINGPROTEIN_Q6_M00720, Klf7.1, Bcl6b.2, Sp4.1, Zfp281.2, Smad3.1, Zfp410.1, Sp4.2, Zfp740.1, Egr1.1, Ascl2.2, SP4_C2H2_full_monomeric_17_1, KLF13_C2H2_full_monomeric_18_1, Klf12_C2H2_DBD_monomeric_15_1, KLF14_C2H2_DBD_monomeric_14_1, KLF16_C2H2_DBD_monomeric_11_1, SP1_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, SP8_C2H2_DBD_monomeric_12_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.01	CGCTAG	NA	1.32	GACGACGC	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.64	CGTTCG	NA	NA	0.68	TCSATCGC	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

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