Nod2 nucleotide-binding oligomerization domain containing 2 (257632)

Symbol Product Feature Type Strand Chr
257632 Nod2 nucleotide-binding oligomerization domain containing 2 protein-coding 8
Synonyms
ACUG | BLAU | CD | Card15 | F830032C23Rik | IBD1 | Nlrc2
GO ID Category Definition Evidence
  • nucleotide binding
  • innate immune response in mucosa
  • activation of immune response
  • cytokine production involved in immune response
  • immune system process
  • immunoglobulin production involved in immunoglobulin mediated immune response
  • positive regulation of dendritic cell antigen processing and presentation
  • negative regulation of T cell mediated immunity
  • positive regulation of dendritic cell cytokine production
  • positive regulation of type 2 immune response
  • negative regulation of inflammatory response to antigenic stimulus
  • positive regulation of humoral immune response mediated by circulating immunoglobulin
  • protein binding
  • ATP binding
  • intracellular
  • cytoplasm
  • cytosol
  • cytoskeleton
  • plasma membrane
  • defense response
  • inflammatory response
  • positive regulation of antibacterial peptide biosynthetic process
  • positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria
  • signal transduction
  • COP9 signalosome
  • positive regulation of cell proliferation
  • detection of biotic stimulus
  • cell surface
  • detection of bacterium
  • endodeoxyribonuclease activity, producing 5'-phosphomonoesters
  • enzyme binding
  • protein kinase binding
  • positive regulation of protein ubiquitination
  • vesicle
  • negative regulation of NF-kappaB transcription factor activity
  • response to peptidoglycan
  • response to muramyl dipeptide
  • response to lipopolysaccharide
  • detection of muramyl dipeptide
  • muramyl dipeptide binding
  • negative regulation of interferon-gamma production
  • negative regulation of interleukin-12 production
  • negative regulation of interleukin-18 production
  • negative regulation of interleukin-2 production
  • negative regulation of tumor necrosis factor production
  • positive regulation of interleukin-1 beta production
  • positive regulation of interleukin-10 production
  • positive regulation of interleukin-12 production
  • positive regulation of interleukin-17 production
  • positive regulation of interleukin-6 production
  • positive regulation of tumor necrosis factor production
  • positive regulation of stress-activated MAPK cascade
  • negative regulation of toll-like receptor 2 signaling pathway
  • activation of MAPK activity involved in innate immune response
  • intracellular signal transduction
  • defense response to bacterium
  • peptidoglycan binding
  • regulation of apoptotic process
  • positive regulation of I-kappaB kinase/NF-kappaB signaling
  • protein complex
  • response to exogenous dsRNA
  • positive regulation of MAPK cascade
  • positive regulation of phosphatidylinositol 3-kinase activity
  • negative regulation of growth of symbiont in host
  • innate immune response
  • positive regulation of innate immune response
  • positive regulation of Notch signaling pathway
  • positive regulation of transcription from RNA polymerase II promoter
  • positive regulation of JNK cascade
  • positive regulation of epithelial cell proliferation
  • CARD domain binding
  • positive regulation of interleukin-1 beta secretion
  • regulation of inflammatory response
  • positive regulation of peptidyl-tyrosine phosphorylation
  • positive regulation of phagocytosis
  • defense response to Gram-positive bacterium
  • positive regulation of B cell activation
  • positive regulation of NF-kappaB transcription factor activity
  • protein oligomerization
  • positive regulation of oxidoreductase activity
  • positive regulation of nitric-oxide synthase biosynthetic process
  • positive regulation of prostaglandin-endoperoxide synthase activity
  • positive regulation of ERK1 and ERK2 cascade
  • nucleotide-binding oligomerization domain containing 2 signaling pathway
  • cellular response to peptidoglycan
  • cellular response to muramyl dipeptide
  • macrophage inflammatory protein-1 alpha production
  • regulation of neutrophil chemotaxis
  • negative regulation of macrophage apoptotic process
  • positive regulation of prostaglandin-E synthase activity
Motif 1 Motif 2 Residual
PITA_126 |
Residual: 
0.27
0.27
PITA_137 |
Residual: 
0.13
0.13
PITA_28 |
Residual: 
0.21
0.21
PITA_67 |
Residual: 
0.18
0.18
TargetScan_107 |
Residual: 
0.13
0.13
TargetScan_38 |
Residual: 
0.11
0.11
Displaying 1 - 6 of 6
Entrez ID STRINGS Network
STRING
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