Module 161 Residual: 0.58

Title Bicluster Model Residual Score
bicluster_0161 v02 0.58 -5.09
Displaying 1 - 18 of 18
Rv0339c POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN

Details for Rv0339c - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.85 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0339c

Tuberculist Genomic Region

Rv0407 F420-dependent glucose-6-phosphate dehydrogenase

Details for Rv0407 - F420-dependent glucose-6-phosphate dehydrogenase

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.92 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0407

Tuberculist Genomic Region

Rv0808 Amidophosphoribosyltransferase (EC 2.4.2.14)

Details for Rv0808 - Amidophosphoribosyltransferase (EC 2.4.2.14)

GO Terms: GO:0004044, GO:0040007

PATRIC Pathways: Alanine, aspartate and glutamate metabolism, Purine metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.08 | In vivo Essential: NA

Go to Gene Page: Rv0808

Tuberculist Genomic Region

Rv0856

Details for Rv0856 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.71 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0856

Tuberculist Genomic Region

Rv0889c Citrate synthase (si) (EC 2.3.3.1)

Details for Rv0889c - Citrate synthase (si) (EC 2.3.3.1)

GO Terms: GO:0004108, GO:0005829

PATRIC Pathways: Citrate cycle (TCA cycle), Glyoxylate and dicarboxylate metabolism

Essentiality: Griffin Essential: 0.78 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0889c

Tuberculist Genomic Region

Rv1035c PROBABLE TRANSPOSASE (FRAGMENT)

Details for Rv1035c - PROBABLE TRANSPOSASE (FRAGMENT)

GO Terms: GO:0005618, GO:0005829, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.27 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1035c

Tuberculist Genomic Region

Rv1738

Details for Rv1738 -

GO Terms: GO:0005829, GO:0005886, GO:0040007, GO:0052572

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.78 | In vitro Essential: 0.16 | In vivo Essential: NA

Go to Gene Page: Rv1738

Tuberculist Genomic Region

Rv1754c

Details for Rv1754c -

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.28 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1754c

Tuberculist Genomic Region

Rv1830

Details for Rv1830 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1830

Tuberculist Genomic Region

Rv2881c Phosphatidate cytidylyltransferase (EC 2.7.7.41)

Details for Rv2881c - Phosphatidate cytidylyltransferase (EC 2.7.7.41)

GO Terms: GO:0004605, GO:0040007

PATRIC Pathways: Glycerophospholipid metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.12 | In vivo Essential: NA

Go to Gene Page: Rv2881c

Tuberculist Genomic Region

Rv2965c Phosphopantetheine adenylyltransferase (EC 2.7.7.3)

Details for Rv2965c - Phosphopantetheine adenylyltransferase (EC 2.7.7.3)

GO Terms: GO:0004595

PATRIC Pathways: Pantothenate and CoA biosynthesis

Essentiality: Griffin Essential: 0.15 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2965c

Tuberculist Genomic Region

Rv2967c Pyruvate carboxyl transferase (EC 6.4.1.1)

Details for Rv2967c - Pyruvate carboxyl transferase (EC 6.4.1.1)

GO Terms: GO:0004736, GO:0005618, GO:0005886, GO:0040007

PATRIC Pathways: Pyruvate metabolism, Citrate cycle (TCA cycle), Reductive carboxylate cycle (CO2 fixation)

Essentiality: Griffin Essential: 0.12 | In vitro Essential: 0.19 | In vivo Essential: NA

Go to Gene Page: Rv2967c

Tuberculist Genomic Region

Rv0007 Possible conserved membrane protein

Details for Rv0007 - Possible conserved membrane protein

GO Terms: GO:0005887

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.16 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0007

Tuberculist Genomic Region

Rv0809 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)

Details for Rv0809 - Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)

GO Terms: GO:0004641, GO:0005886

PATRIC Pathways: Purine metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0809

Tuberculist Genomic Region

Rv0949 ATP-dependent DNA helicase UvrD/PcrA

Details for Rv0949 - ATP-dependent DNA helicase UvrD/PcrA

GO Terms: GO:0003677, GO:0005524, GO:0004003, GO:0006281, GO:0000287, GO:0005515, GO:0005618, GO:0005886, GO:0006302, GO:0008094, GO:0009650, GO:0016887, GO:0032564, GO:0033202, GO:0040007, GO:0043140

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.17 | In vivo Essential: NA

Go to Gene Page: Rv0949

Tuberculist Genomic Region

Rv1781c 4-alpha-glucanotransferase (amylomaltase) (EC 2.4.1.25)

Details for Rv1781c - 4-alpha-glucanotransferase (amylomaltase) (EC 2.4.1.25)

GO Terms: GO:0005829

PATRIC Pathways: Starch and sucrose metabolism

Essentiality: Griffin Essential: 1.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1781c

Tuberculist Genomic Region

Rv1919c

Details for Rv1919c -

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.83 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1919c

Tuberculist Genomic Region

Rv3113 hydrolase, haloacid dehalogenase-like family

Details for Rv3113 - hydrolase, haloacid dehalogenase-like family

GO Terms: GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.22 | In vitro Essential: 0.12 | In vivo Essential: NA

Go to Gene Page: Rv3113

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 1500 e-value: 11000
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
GO:0072522 purine-containing compound biosynthetic ...
Displaying 1 - 26 of 26
GO:0005886 |

plasma membrane

GO:0004044 |

amidophosphoribosyltransferase activity

GO:0040007 |

growth

GO:0004108 |

citrate (Si)-synthase activity

GO:0005829 |

cytosol

GO:0005618 |

cell wall

GO:0052572 |

response to host immune response

GO:0004605 |

phosphatidate cytidylyltransferase activity

GO:0004595 |

pantetheine-phosphate adenylyltransferase activity

GO:0004736 |

pyruvate carboxylase activity

GO:0005887 |

integral to plasma membrane

GO:0004641 |

phosphoribosylformylglycinamidine cyclo-ligase activity

GO:0003677 |

DNA binding

GO:0005524 |

ATP binding

GO:0004003 |

ATP-dependent DNA helicase activity

GO:0006281 |

DNA repair

GO:0000287 |

magnesium ion binding

GO:0005515 |

protein binding

GO:0006302 |

double-strand break repair

GO:0008094 |

DNA-dependent ATPase activity

GO:0009650 |

UV protection

GO:0016887 |

ATPase activity

GO:0032564 |

dATP binding

GO:0033202 |

DNA helicase complex

GO:0043140 |

ATP-dependent 3'-5' DNA helicase activity