Module 276 Residual: 0.47

Title Bicluster Model Residual Score
bicluster_0276 v02 0.47 -15.97
Displaying 1 - 13 of 13
Rv0824c Fatty acid desaturase occurring in virulence cluster

Details for Rv0824c - Fatty acid desaturase occurring in virulence cluster

GO Terms: GO:0045300, GO:0005618, GO:0005829, GO:0005886, GO:0040007, GO:0052572

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.13 | In vivo Essential: NA

Go to Gene Page: Rv0824c

Tuberculist Genomic Region

Rv1094 Fatty acid desaturase occurring in virulence cluster

Details for Rv1094 - Fatty acid desaturase occurring in virulence cluster

GO Terms: GO:0005829, GO:0005886, GO:0040007, GO:0042803, GO:0046872

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.12 | In vivo Essential: NA

Go to Gene Page: Rv1094

Tuberculist Genomic Region

Rv1992c Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4)

Details for Rv1992c - Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4)

GO Terms: GO:0005886, GO:0005887

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.99 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1992c

Tuberculist Genomic Region

Rv1993c

Details for Rv1993c -

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.71 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1993c

Tuberculist Genomic Region

Rv2930 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)

Details for Rv2930 - Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)

GO Terms: GO:0004467, GO:0005886, GO:0044119, GO:0052572, GO:0070566, GO:0071770

PATRIC Pathways: Fatty acid metabolism

Essentiality: Griffin Essential: 0.08 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2930

Tuberculist Genomic Region

Rv2934 Phenolpthiocerol synthesis type-I polyketide synthase PpsD

Details for Rv2934 - Phenolpthiocerol synthesis type-I polyketide synthase PpsD

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.99 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2934

Tuberculist Genomic Region

Rv2935 Malonyl CoA-acyl carrier protein transacylase (EC 2.3.1.39)

Details for Rv2935 - Malonyl CoA-acyl carrier protein transacylase (EC 2.3.1.39)

GO Terms: GO:0005618, GO:0005886

PATRIC Pathways: Fatty acid biosynthesis

Essentiality: Griffin Essential: 1.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2935

Tuberculist Genomic Region

Rv2936 Daunorubicin-DIM-transport ATP-binding protein ABC transporter DrrA

Details for Rv2936 - Daunorubicin-DIM-transport ATP-binding protein ABC transporter DrrA

GO Terms: GO:0005524, GO:0005886, GO:0006869, GO:0044119

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.91 | In vitro Essential: NA | In vivo Essential: 0.22

Go to Gene Page: Rv2936

Tuberculist Genomic Region

Rv2937 Daunorubicin-DIM-transport integral membrane protein ABC transporter DrrB

Details for Rv2937 - Daunorubicin-DIM-transport integral membrane protein ABC transporter DrrB

GO Terms: GO:0005886, GO:0008610, GO:0071766

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.31 | In vitro Essential: NA | In vivo Essential: 0.31

Go to Gene Page: Rv2937

Tuberculist Genomic Region

Rv2938 Daunorubicin-DIM-transport integral membrane protein ABC transporter DrrC

Details for Rv2938 - Daunorubicin-DIM-transport integral membrane protein ABC transporter DrrC

GO Terms: GO:0044119, GO:0052572

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.96 | In vitro Essential: NA | In vivo Essential: 0.28

Go to Gene Page: Rv2938

Tuberculist Genomic Region

Rv2939 Putative conserved polyketide synthase-associated protein PapA5

Details for Rv2939 - Putative conserved polyketide synthase-associated protein PapA5

GO Terms: GO:0005515, GO:0008415, GO:0008610, GO:0071770

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.84 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2939

Tuberculist Genomic Region

Rv3407

Details for Rv3407 -

GO Terms: GO:0045927

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.78 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3407

Tuberculist Genomic Region

Rv3408

Details for Rv3408 -

GO Terms: GO:0017148, GO:0045926

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.90 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3408

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 93 e-value: 170
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
GO:0015238 | GO:0090484 drug transmembrane transporter activity | drug transporter activity
Displaying 1 - 22 of 22
GO:0045300 |

acyl-[acyl-carrier-protein] desaturase activity

GO:0005618 |

cell wall

GO:0005829 |

cytosol

GO:0005886 |

plasma membrane

GO:0040007 |

growth

GO:0052572 |

response to host immune response

GO:0042803 |

protein homodimerization activity

GO:0046872 |

metal ion binding

GO:0005887 |

integral to plasma membrane

GO:0004467 |

long-chain fatty acid-CoA ligase activity

GO:0044119 |

growth of symbiont in host cell

GO:0070566 |

adenylyltransferase activity

GO:0071770 |

DIM/DIP cell wall layer assembly

GO:0005524 |

ATP binding

GO:0006869 |

lipid transport

GO:0008610 |

lipid biosynthetic process

GO:0071766 |

Actinobacterium-type cell wall biogenesis

GO:0005515 |

protein binding

GO:0008415 |

NA

GO:0045927 |

positive regulation of growth

GO:0017148 |

negative regulation of translation

GO:0045926 |

negative regulation of growth