Module 367 Residual: 0.59

Title Bicluster Model Residual Score
bicluster_0367 v02 0.59 -19.12
Displaying 1 - 16 of 16
Rv1093 Serine hydroxymethyltransferase 1 (EC 2.1.2.1)

Details for Rv1093 - Serine hydroxymethyltransferase 1 (EC 2.1.2.1)

GO Terms: GO:0004372, GO:0004372, GO:0005886, GO:0006544, GO:0006563, GO:0030170, GO:0042783, GO:0042803

PATRIC Pathways: Cyanoamino acid metabolism, Glycine, serine and threonine metabolism, One carbon pool by folate, Methane metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1093

Tuberculist Genomic Region

Rv2840c COG2740: Predicted nucleic-acid-binding protein implicated in transcription termination

Details for Rv2840c - COG2740: Predicted nucleic-acid-binding protein implicated in transcription termination

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.20 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2840c

Tuberculist Genomic Region

Rv2841c Transcription termination protein NusA

Details for Rv2841c - Transcription termination protein NusA

GO Terms: GO:0003723, GO:0003676, GO:0003723, GO:0005886, GO:0030401, GO:0031564, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.05 | In vivo Essential: NA

Go to Gene Page: Rv2841c

Tuberculist Genomic Region

Rv2842c COG0779: clustered with transcription termination protein NusA

Details for Rv2842c - COG0779: clustered with transcription termination protein NusA

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.20 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2842c

Tuberculist Genomic Region

Rv0002 DNA polymerase III beta subunit (EC 2.7.7.7)

Details for Rv0002 - DNA polymerase III beta subunit (EC 2.7.7.7)

GO Terms: GO:0003887, GO:0005576

PATRIC Pathways: Pyrimidine metabolism, Purine metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0002

Tuberculist Genomic Region

Rv0003 DNA recombination and repair protein RecF

Details for Rv0003 - DNA recombination and repair protein RecF

GO Terms: GO:0005829, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.13 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0003

Tuberculist Genomic Region

Rv0237 Beta-hexosaminidase (EC 3.2.1.52)

Details for Rv0237 - Beta-hexosaminidase (EC 3.2.1.52)

GO Terms: GO:0005576, GO:0005618

PATRIC Pathways: Glycosaminoglycan degradation, Amino sugar and nucleotide sugar metabolism, Glycosphingolipid biosynthesis - globo series, High-mannose type N-glycan biosynthesis, Glycosphingolipid biosynthesis - ganglio series

Essentiality: Griffin Essential: 0.59 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0237

Tuberculist Genomic Region

Rv2274c

Details for Rv2274c -

GO Terms: GO:0040008

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.68 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2274c

Tuberculist Genomic Region

Rv2275

Details for Rv2275 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.26 | In vitro Essential: NA | In vivo Essential: 0.33

Go to Gene Page: Rv2275

Tuberculist Genomic Region

Rv2450c Putative saccharopine dehydrogenase

Details for Rv2450c - Putative saccharopine dehydrogenase

GO Terms: GO:0005576, GO:0010628, GO:0010629, GO:0040010

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.87 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2450c

Tuberculist Genomic Region

Rv2451

Details for Rv2451 -

GO Terms: GO:0005829

PATRIC Pathways: NA

Essentiality: Griffin Essential: 0.63 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2451

Tuberculist Genomic Region

Rv2843 PROBABLE CONSERVED TRANSMEMBRANE ALANINE RICH PROTEIN

Details for Rv2843 - PROBABLE CONSERVED TRANSMEMBRANE ALANINE RICH PROTEIN

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.06 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2843

Tuberculist Genomic Region

Rv2844

Details for Rv2844 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.15 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2844

Tuberculist Genomic Region

Rv3434c POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN

Details for Rv3434c - POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.75 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3434c

Tuberculist Genomic Region

Rv3435c PROBABLE CONSERVED TRANSMEMBRANE PROTEIN

Details for Rv3435c - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.56 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3435c

Tuberculist Genomic Region

Rv3782 Putative glycosyl transferase

Details for Rv3782 - Putative glycosyl transferase

GO Terms: GO:0005886, GO:0008378, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.04 | In vivo Essential: NA

Go to Gene Page: Rv3782

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 0.0000000000019 e-value: 0.00026
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
GO:0006457 | GO:0004658 protein folding | propionyl-CoA carboxylase activity
Displaying 1 - 22 of 22
GO:0004372 |

glycine hydroxymethyltransferase activity

GO:0005886 |

plasma membrane

GO:0006544 |

glycine metabolic process

GO:0006563 |

L-serine metabolic process

GO:0030170 |

pyridoxal phosphate binding

GO:0042783 |

active evasion of host immune response

GO:0042803 |

protein homodimerization activity

GO:0003723 |

RNA binding

GO:0003676 |

nucleic acid binding

GO:0030401 |

transcription antiterminator activity

GO:0031564 |

transcription antitermination

GO:0040007 |

growth

GO:0003887 |

DNA-directed DNA polymerase activity

GO:0005576 |

extracellular region

GO:0005829 |

cytosol

GO:0005618 |

cell wall

GO:0040008 |

regulation of growth

GO:0010628 |

positive regulation of gene expression

GO:0010629 |

negative regulation of gene expression

GO:0040010 |

positive regulation of growth rate

GO:0008378 |

galactosyltransferase activity