Module 480 Residual: 0.52

Title Bicluster Model Residual Score
bicluster_0480 v02 0.52 -23.24
Displaying 1 - 16 of 16
Rv1559 Threonine dehydratase (EC 4.3.1.19)

Details for Rv1559 - Threonine dehydratase (EC 4.3.1.19)

GO Terms: GO:0004794, GO:0005886

PATRIC Pathways: Glycine, serine and threonine metabolism, Valine, leucine and isoleucine biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1559

Tuberculist Genomic Region

Rv2996c D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)

Details for Rv2996c - D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)

GO Terms: GO:0004617, GO:0004617, GO:0005886, GO:0040007, GO:0051289

PATRIC Pathways: Glycine, serine and threonine metabolism, Methane metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.07 | In vivo Essential: NA

Go to Gene Page: Rv2996c

Tuberculist Genomic Region

Rv0788 Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)

Details for Rv0788 - Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)

GO Terms: GO:0004642, GO:0005886, GO:0040007

PATRIC Pathways: Purine metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.08 | In vivo Essential: NA

Go to Gene Page: Rv0788

Tuberculist Genomic Region

Rv0863

Details for Rv0863 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.83 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0863

Tuberculist Genomic Region

Rv0931c Serine/threonine-protein kinase pknD (EC 2.7.11.1)

Details for Rv0931c - Serine/threonine-protein kinase pknD (EC 2.7.11.1)

GO Terms: GO:0004672, GO:0004674, GO:0005829, GO:0005886, GO:0005887, GO:0009405, GO:0030145, GO:0032091, GO:0042803, GO:0043085, GO:0043086

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 1.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0931c

Tuberculist Genomic Region

Rv0932c Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1)

Details for Rv0932c - Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1)

GO Terms: GO:0006810, GO:0005215, GO:0005576, GO:0005886, GO:0006817

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.79 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0932c

Tuberculist Genomic Region

Rv0933 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1)

Details for Rv0933 - Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1)

GO Terms: GO:0016887, GO:0005524, GO:0005524, GO:0005886, GO:0016887

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.32 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0933

Tuberculist Genomic Region

Rv0934 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1)

Details for Rv0934 - Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1)

GO Terms: GO:0005515, GO:0005576, GO:0005618, GO:0005829, GO:0005886, GO:0006817, GO:0016036, GO:0042301

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 1.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0934

Tuberculist Genomic Region

Rv0935 Phosphate transport system permease protein PstC (TC 3.A.1.7.1)

Details for Rv0935 - Phosphate transport system permease protein PstC (TC 3.A.1.7.1)

GO Terms: GO:0005215, GO:0016020, GO:0006810

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.95 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0935

Tuberculist Genomic Region

Rv0936 Phosphate transport system permease protein PstA (TC 3.A.1.7.1)

Details for Rv0936 - Phosphate transport system permease protein PstA (TC 3.A.1.7.1)

GO Terms: GO:0005215, GO:0016020, GO:0006810

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.92 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0936

Tuberculist Genomic Region

Rv1156

Details for Rv1156 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.78 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1156

Tuberculist Genomic Region

Rv1324 COG3118: Thioredoxin domain-containing protein EC-YbbN

Details for Rv1324 - COG3118: Thioredoxin domain-containing protein EC-YbbN

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.09 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1324

Tuberculist Genomic Region

Rv1558 AclJ

Details for Rv1558 - AclJ

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.92 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1558

Tuberculist Genomic Region

Rv2684 Na+/H+ antiporter NhaD type

Details for Rv2684 - Na+/H+ antiporter NhaD type

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.92 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2684

Tuberculist Genomic Region

Rv2685 Na+/H+ antiporter NhaD type

Details for Rv2685 - Na+/H+ antiporter NhaD type

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.85 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2685

Tuberculist Genomic Region

Rv3004 Low molecular weight protein antigen 6

Details for Rv3004 - Low molecular weight protein antigen 6

GO Terms: GO:0005576

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.40 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3004

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 0.3 e-value: 53
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
No enrichment
Displaying 1 - 28 of 28
GO:0004794 |

L-threonine ammonia-lyase activity

GO:0005886 |

plasma membrane

GO:0004617 |

phosphoglycerate dehydrogenase activity

GO:0040007 |

growth

GO:0051289 |

protein homotetramerization

GO:0004642 |

phosphoribosylformylglycinamidine synthase activity

GO:0004672 |

protein kinase activity

GO:0004674 |

protein serine/threonine kinase activity

GO:0005829 |

cytosol

GO:0005887 |

integral to plasma membrane

GO:0009405 |

pathogenesis

GO:0030145 |

manganese ion binding

GO:0032091 |

negative regulation of protein binding

GO:0042803 |

protein homodimerization activity

GO:0043085 |

positive regulation of catalytic activity

GO:0043086 |

negative regulation of catalytic activity

GO:0006810 |

transport

GO:0005215 |

transporter activity

GO:0005576 |

extracellular region

GO:0006817 |

phosphate ion transport

GO:0016887 |

ATPase activity

GO:0005524 |

ATP binding

GO:0005515 |

protein binding

GO:0005618 |

cell wall

GO:0016036 |

cellular response to phosphate starvation

GO:0042301 |

phosphate ion binding

GO:0016020 |

membrane