Rv3681c WhiB-type transcription regulator

Rv3681c (WhiB-type transcription regulator) is predicted to be co-regulated in modules bicluster_0400 with residual 0.51 and bicluster_0421 with residual 0.58.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.01 and 0.12 for bicluster_0400 and 360.00 and 130.00 for bicluster_0421 respectively.

These modules are enriched for following go terms: carboxypeptidase activity, thiosulfate sulfurtransferase activity, unfolded protein binding, exopeptidase activity .

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 31 - 40 of 56
Gene Target Differential Expression Distance Expression pvalue Type
Adenine phosphoribosyltransferase (EC 2.4.2.7)
No 46 -0.03 0.999973 Primary.TSS
Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)
No -17 -0.09 0.999973 Primary.TSS
No 37 -0.86 0.999973 Primary.TSS
RNA polymerase sigma factor SigB
No -70 -0.08 0.999973 Primary.TSS
PE family protein
No 59 -0.29 0.999973 CDS
Transcriptional regulator, AsnC family
No 46 0.58 0.999973 Internal.TSS
Transcriptional regulator, AsnC family
No 4 0.58 0.999973 CDS
Alanine dehydrogenase (EC 1.4.1.1)
No -41 0.15 0.999973 Primary.TSS
LSU ribosomal protein L19p
No 66 -0.05 0.999973 Primary.TSS
Putative lipoprotein lppW precursor
No -34 0.28 0.999973 Primary.TSS
not assigned to any KEGG Pathway.
GO:0005618

cell wall

cell wall

Details: 
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan.
GO Category: 
cellular_component
320
Total items in this category:  
GO:0042803

protein homodimerization activity

protein homodimerization activity

Details: 
Interacting selectively and non-covalently with an identical protein to form a homodimer.
GO Category: 
molecular_function
83
Total items in this category:  
GO:0047134

protein-disulfide reductase activity

protein-disulfide reductase activity

Details: 
Catalysis of the reaction: protein-dithiol + NAD(P)+ = protein-disulfide + NAD(P)H + H+.
GO Category: 
molecular_function
2
Total items in this category:  
GO:0051539

4 iron, 4 sulfur cluster binding

4 iron, 4 sulfur cluster binding

Details: 
Interacting selectively and non-covalently with a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
GO Category: 
molecular_function
5
Total items in this category:  
No TFOE experiment results were found

TRIP log2 fold abundance change

NA