Module 162 Residual: 0.54

Title Bicluster Model Residual Score
bicluster_0162 v02 0.54 -10.83
Displaying 1 - 19 of 19
Rv0173 MCE-family lipoprotein LprK (MCE-family lipoprotein Mce1e)

Details for Rv0173 - MCE-family lipoprotein LprK (MCE-family lipoprotein Mce1e)

GO Terms: GO:0005576, GO:0044117

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.87 | In vitro Essential: NA | In vivo Essential: 0.16

Go to Gene Page: Rv0173

Tuberculist Genomic Region

Rv0175 FIG033430: Probable conserved MCE associated membrane protein

Details for Rv0175 - FIG033430: Probable conserved MCE associated membrane protein

GO Terms: GO:0005576, GO:0005886, GO:0005887, GO:0044117

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.90 | In vitro Essential: NA | In vivo Essential: 0.28

Go to Gene Page: Rv0175

Tuberculist Genomic Region

Rv0176 FIG033285: Conserved MCE associated transmembrane protein

Details for Rv0176 - FIG033285: Conserved MCE associated transmembrane protein

GO Terms: GO:0005886, GO:0044117, GO:0044119

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.98 | In vitro Essential: NA | In vivo Essential: 0.22

Go to Gene Page: Rv0176

Tuberculist Genomic Region

Rv1297 Transcription termination factor Rho

Details for Rv1297 - Transcription termination factor Rho

GO Terms: GO:0016469, GO:0003715, GO:0006353, GO:0003723, GO:0005524, GO:0015986, GO:0005618, GO:0005886, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.03 | In vivo Essential: NA

Go to Gene Page: Rv1297

Tuberculist Genomic Region

Rv1324 COG3118: Thioredoxin domain-containing protein EC-YbbN

Details for Rv1324 - COG3118: Thioredoxin domain-containing protein EC-YbbN

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.09 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1324

Tuberculist Genomic Region

Rv1388 integration host factor

Details for Rv1388 - integration host factor

GO Terms: GO:0005618, GO:0005829, GO:0005886, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.40 | In vitro Essential: 0.08 | In vivo Essential: NA

Go to Gene Page: Rv1388

Tuberculist Genomic Region

Rv2051c Apolipoprotein N-acyltransferase (EC 2.3.1.-) in lipid-linked oligosaccharide synthesis cluster / Dolichol-phosphate mannosyltransferase (EC 2.4.1.83) in lipid-linked oligosaccharide synthesis cluster
Rv2093c Twin-arginine translocation protein TatC

Details for Rv2093c - Twin-arginine translocation protein TatC

GO Terms: GO:0005829, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.12 | In vivo Essential: NA

Go to Gene Page: Rv2093c

Tuberculist Genomic Region

Rv2334 Cysteine synthase (EC 2.5.1.47)

Details for Rv2334 - Cysteine synthase (EC 2.5.1.47)

GO Terms: GO:0004124, GO:0004124, GO:0005515, GO:0005576, GO:0030170, GO:0042803

PATRIC Pathways: Sulfur metabolism, Cysteine and methionine metabolism

Essentiality: Griffin Essential: 0.21 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2334

Tuberculist Genomic Region

Rv2335 Serine acetyltransferase (EC 2.3.1.30)

Details for Rv2335 - Serine acetyltransferase (EC 2.3.1.30)

GO Terms: GO:0009001, GO:0005515

PATRIC Pathways: Sulfur metabolism, Cysteine and methionine metabolism

Essentiality: Griffin Essential: 0.17 | In vitro Essential: NA | In vivo Essential: 0.33

Go to Gene Page: Rv2335

Tuberculist Genomic Region

Rv2942 Putative membrane protein MmpL7

Details for Rv2942 - Putative membrane protein MmpL7

GO Terms: GO:0005887, GO:0006855, GO:0006869, GO:0044119, GO:0052572

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.93 | In vitro Essential: NA | In vivo Essential: 0.26

Go to Gene Page: Rv2942

Tuberculist Genomic Region

Rv2957 PGL/p-HBAD biosynthesis glycosyltransferase

Details for Rv2957 - PGL/p-HBAD biosynthesis glycosyltransferase

GO Terms: GO:0009247, GO:0016758

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.91 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2957

Tuberculist Genomic Region

Rv3295 Transcriptional regulator, TetR family

Details for Rv3295 - Transcriptional regulator, TetR family

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.95 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3295

Tuberculist Genomic Region

Rv3401 Maltose phosphorylase (EC 2.4.1.8) / Trehalose phosphorylase (EC 2.4.1.64)

Details for Rv3401 - Maltose phosphorylase (EC 2.4.1.8) / Trehalose phosphorylase (EC 2.4.1.64)

GO Terms: GO:0005886

PATRIC Pathways: Starch and sucrose metabolism, Starch and sucrose metabolism

Essentiality: Griffin Essential: 0.99 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3401

Tuberculist Genomic Region

Rv3489

Details for Rv3489 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.22 | In vitro Essential: NA | In vivo Essential: 0.30

Go to Gene Page: Rv3489

Tuberculist Genomic Region

Rv3490 Alpha,alpha-trehalose-phosphate synthase [UDP-forming] (EC 2.4.1.15)

Details for Rv3490 - Alpha,alpha-trehalose-phosphate synthase [UDP-forming] (EC 2.4.1.15)

GO Terms: GO:0003825, GO:0003825, GO:0005618, GO:0005886, GO:0030145, GO:0040007, GO:0047260, GO:0051289

PATRIC Pathways: Starch and sucrose metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.07 | In vivo Essential: NA

Go to Gene Page: Rv3490

Tuberculist Genomic Region

Rv3811 Putative uncharacterized protein BCG_3873

Details for Rv3811 - Putative uncharacterized protein BCG_3873

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.96 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3811

Tuberculist Genomic Region

Rv0006 DNA gyrase subunit A (EC 5.99.1.3)

Details for Rv0006 - DNA gyrase subunit A (EC 5.99.1.3)

GO Terms: GO:0003918, GO:0000287, GO:0003918, GO:0005515, GO:0005524, GO:0005886, GO:0046982

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0006

Tuberculist Genomic Region

Rv3921c Inner membrane protein translocase component YidC, long form

Details for Rv3921c - Inner membrane protein translocase component YidC, long form

GO Terms: GO:0005887, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.13 | In vivo Essential: NA

Go to Gene Page: Rv3921c

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 45 e-value: 5400
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
GO:0006535 | GO:0019344 | GO:0006534 | GO:0006563 cysteine biosynthetic process from serin... | cysteine biosynthetic process | cysteine metabolic process | L-serine metabolic process
Displaying 1 - 33 of 33
GO:0005576 |

extracellular region

GO:0044117 |

growth of symbiont in host

GO:0005886 |

plasma membrane

GO:0005887 |

integral to plasma membrane

GO:0044119 |

growth of symbiont in host cell

GO:0016469 |

proton-transporting two-sector ATPase complex

GO:0003715 |

transcription termination factor activity

GO:0006353 |

DNA-dependent transcription, termination

GO:0003723 |

RNA binding

GO:0005524 |

ATP binding

GO:0015986 |

ATP synthesis coupled proton transport

GO:0005618 |

cell wall

GO:0040007 |

growth

GO:0005829 |

cytosol

GO:0004582 |

dolichyl-phosphate beta-D-mannosyltransferase activity

GO:0004124 |

cysteine synthase activity

GO:0005515 |

protein binding

GO:0030170 |

pyridoxal phosphate binding

GO:0042803 |

protein homodimerization activity

GO:0009001 |

serine O-acetyltransferase activity

GO:0006855 |

drug transmembrane transport

GO:0006869 |

lipid transport

GO:0052572 |

response to host immune response

GO:0009247 |

glycolipid biosynthetic process

GO:0016758 |

transferase activity, transferring hexosyl groups

GO:0003825 |

alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity

GO:0030145 |

manganese ion binding

GO:0047260 |

alpha,alpha-trehalose-phosphate synthase (GDP-forming) activity

GO:0051289 |

protein homotetramerization

GO:0003918 |

DNA topoisomerase (ATP-hydrolyzing) activity

GO:0000287 |

magnesium ion binding

GO:0046982 |

protein heterodimerization activity