Module 208 Residual: 0.56

Title Bicluster Model Residual Score
bicluster_0208 v02 0.56 -8.50
Displaying 1 - 15 of 15
Rv1611 Indole-3-glycerol phosphate synthase (EC 4.1.1.48)

Details for Rv1611 - Indole-3-glycerol phosphate synthase (EC 4.1.1.48)

GO Terms: GO:0004425, GO:0000287, GO:0004425, GO:0005886, GO:0040007, GO:0046391

PATRIC Pathways: Phenylalanine, tyrosine and tryptophan biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.02 | In vivo Essential: NA

Go to Gene Page: Rv1611

Tuberculist Genomic Region

Rv1614 Prolipoprotein diacylglyceryl transferase (EC 2.4.99.-)

Details for Rv1614 - Prolipoprotein diacylglyceryl transferase (EC 2.4.99.-)

GO Terms: GO:0005887, GO:0040007

PATRIC Pathways: Glycosphingolipid biosynthesis - ganglio series, Glycosphingolipid biosynthesis - lacto and neolacto series, Glycosphingolipid biosynthesis - globo series

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.04 | In vivo Essential: NA

Go to Gene Page: Rv1614

Tuberculist Genomic Region

Rv2067c Methyltransferase type 12

Details for Rv2067c - Methyltransferase type 12

GO Terms: GO:0005618, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.12 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2067c

Tuberculist Genomic Region

Rv3438

Details for Rv3438 -

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.10 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3438

Tuberculist Genomic Region

Rv3718c

Details for Rv3718c -

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.71 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3718c

Tuberculist Genomic Region

Rv2102

Details for Rv2102 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.78 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2102

Tuberculist Genomic Region

Rv2144c Probable transmembrane protein

Details for Rv2144c - Probable transmembrane protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.71 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2144c

Tuberculist Genomic Region

Rv2213 Cytosol aminopeptidase PepA (EC 3.4.11.1)

Details for Rv2213 - Cytosol aminopeptidase PepA (EC 3.4.11.1)

GO Terms: GO:0004178, GO:0005886

PATRIC Pathways: Glutathione metabolism

Essentiality: Griffin Essential: 0.40 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2213

Tuberculist Genomic Region

Rv2911 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4)

Details for Rv2911 - D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4)

GO Terms: GO:0009002

PATRIC Pathways: Peptidoglycan biosynthesis

Essentiality: Griffin Essential: 0.50 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2911

Tuberculist Genomic Region

Rv3227 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)

Details for Rv3227 - 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)

GO Terms: GO:0003866, GO:0003866, GO:0005886

PATRIC Pathways: Phenylalanine, tyrosine and tryptophan biosynthesis

Essentiality: Griffin Essential: 0.02 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3227

Tuberculist Genomic Region

Rv3228 Ribosome small subunit-stimulated GTPase EngC

Details for Rv3228 - Ribosome small subunit-stimulated GTPase EngC

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.25 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3228

Tuberculist Genomic Region

Rv3584 Lipoprotein LpqE

Details for Rv3584 - Lipoprotein LpqE

GO Terms: GO:0005576, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.59 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3584

Tuberculist Genomic Region

Rv3686c

Details for Rv3686c -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.83 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3686c

Tuberculist Genomic Region

Rv3726 2,3-butanediol dehydrogenase, R-alcohol forming, (R)- and (S)-acetoin-specific (EC 1.1.1.4)

Details for Rv3726 - 2,3-butanediol dehydrogenase, R-alcohol forming, (R)- and (S)-acetoin-specific (EC 1.1.1.4)

GO Terms: GO:0005886

PATRIC Pathways: Butanoate metabolism

Essentiality: Griffin Essential: 0.64 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3726

Tuberculist Genomic Region

Rv3803c Antigen 85-C precursor (85C) (Antigen 85 complex C) (Ag85C) (Mycolyl transferase 85C) (EC 2.3.1.-)
Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 2200 e-value: 230
Displaying 1 - 1 of 1
Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system
regulates 24 modules
Weight: 
0.13
up-regulates
HTH-type transcriptional regulator
regulates 17 modules
Weight: 
-0.12
down-regulates
Two-component response regulator
regulates 21 modules
Weight: 
-0.11
down-regulates
Transcriptional regulator, TetR family
regulates 19 modules
Weight: 
0.10
up-regulates
Arginine pathway regulatory protein ArgR, repressor of arg regulon
regulates 31 modules
Weight: 
0.09
up-regulates
RNA polymerase sigma factor SigB
regulates 18 modules
Weight: 
-0.09
down-regulates
Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR
regulates 90 modules
Weight: 
0.08
up-regulates
POSSIBLE HISTONE-LIKE PROTEIN HNS
regulates 12 modules
Weight: 
0.08
up-regulates
\Transcriptional regulator, TetR family\\\""
regulates 32 modules
Weight: 
0.08
up-regulates
DNA-binding response regulator, LuxR family
regulates 29 modules
Weight: 
0.07
up-regulates
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
regulates 28 modules
Weight: 
0.07
up-regulates
Single-stranded DNA-binding protein
regulates 26 modules
Weight: 
0.07
up-regulates
regulates 43 modules
Weight: 
0.06
up-regulates
regulates 18 modules
Weight: 
0.03
up-regulates
response regulator
regulates 69 modules
Weight: 
0.03
up-regulates
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
No enrichment
Displaying 1 - 12 of 12
GO:0004425 |

indole-3-glycerol-phosphate synthase activity

GO:0000287 |

magnesium ion binding

GO:0005886 |

plasma membrane

GO:0040007 |

growth

GO:0046391 |

5-phosphoribose 1-diphosphate metabolic process

GO:0005887 |

integral to plasma membrane

GO:0005618 |

cell wall

GO:0004178 |

leucyl aminopeptidase activity

GO:0009002 |

serine-type D-Ala-D-Ala carboxypeptidase activity

GO:0003866 |

3-phosphoshikimate 1-carboxyvinyltransferase activity

GO:0005576 |

extracellular region